Bioassay-guided fractionation of organic extracts Cladosporium herbarum, isolated from the marine sponge Callyspongia aerizusa, yielded two new macrolide metabolites: pandangolide 3 and 4 (1 2) known fungal metabolites 2 (3), cladospolide B (4), iso-cladospolide (5). Also were antimicrobially active (against Bacillus subtilis Staphylococcus aureus) furan carboxylic acids: Sumiki's acid (6) its derivative, acetyl (7). All structures elucidated by spectroscopic methods.

Exploration of plant combinations could be an alternative approach for diabetes treatment. The aim this study is to evaluate the hypoglycemic effect combination A. indica and G. procumbens ethanolic extracts in alloxan-induced diabetic rats.Powder leaves were macerated with ethanol 70%. Determination rutin quercetin performed by TLC-densitometry. Hyperglycemia rats was induced intraperitoneal injection alloxan monohydrate at a single dose 150 mg/kgBW. treated 3 dosage variation 15 days....

The effect of ethanolic extract Morinda citrifolia leaves and fruit on blood pressure in dexamethasone-induced hypertension rat was evaluated. Total phenolic content (MCLEE) (MCFEE) 1.789 ± 0.116 1.677 0.051 mg gallic acid equivalents per gram sample, respectively. Rutin level MCLEE 0.92 0.19%, scopoletin MCFEE 0.46 0.05%. MCLEE, MCFEE, its combination significantly decreased the hypertensive rats. group showed highest hypotensive activity by lowering systolic 16.71 3.95%, diastolic 21.49...

Copper is a well-known material that used for various applications owing to its good thermal conductivity and properties. The development of porous metals still challenge in the field materials research. aim this work was investigate effects sintering temperature ratio copper powder egg yolk on production copper. In study, metallurgy route followed produce metal with as foaming agent. green mixture dried at 160 ℃, while temperatures were 750, 800, 850 ℃. Based test results, maximum porosity...

In this paper, the optimization of welding processes for dissimilar materials AISI 4340 and ST 36 is examined, addressing complexities challenges associated with such joints. The Taguchi Method employed to investigate key parameters, including electrode type, current, joint speed. Orthogonal arrays are utilized manage experimental data efficiently, facilitating clear conclusions. Sample plates machined specific dimensions, conducted using Shielded Metal Arc Welding method various types....

Penyandang disabilitas semakin tahun meningkat. Disabilitas sebagai suatu kondisi ketidakmampuan penyandang melaksanakan peran dan fungsi dalam kehidupannya sehari-hari. Hal ini berkaitan dengan kurangnya kemampuan anggota tubuh untuk menjalankan secara normal yang dapat disebabkan oleh luka, penyakit, maupun pertumbuhan tidak sempurna. berjalan dibantu melakukan modifikasi alat bantu membutuhkan strategi pelatihan agar pasien bisa mencapai ambulasi optimal pada saat pergerakan. Kegiatan...

One of problem from anti acne cream formula containing Epigallocatechin gallate (EGCG) green tea leaves is EGCG stability.The unstable to heat and easily oxidated.However, the main marker substance related antibacterial activity.This study aimed determine stability its activity.The testing was obtained during extraction process by adding phosphoric acid buffer, pH 4 buffer solution control.The these groups then tested at 2, 25 40°C temperature.Evaluation for absorbance changing UV-VIS...

Coleus amboinicus is a medicinal plant traditionally used to treat various diseases such as throat infection, cough and fever, diarrhea, nasal congestion digestive problems. The was explored for endophytic fungi producing antimicrobial agents.Screening agents conducted using agar plug method activity of promising ethyl acetate extracts determined by disc diffusion assay. Thin layer chromatography (TLC) - bioautography performed localize the bioactive components within extract. TLC...

Abstract From the marine sponge Callyspongia aerizusa collected from Sea of Bali, Indonesia, fungal isolates Drechslera hawaiiensis were obtained. Culture filtrates fungus yielded four spiciferone derivatives which include A (1) and B (2), two other novel including spiciferol (3) is an alcohol congener compound 4 monocyclic featuring a butoxyl side chain. The structures compounds established on basis NMR spectroscopic ( 1 H , 13 C, COSY) mass spectrometric (EIMS) data.

The aim of the research is to analyze differences in subset T lymphocytes and NK cells at various degrees disease severity order be used stratification patients’ management predict outcomes for optimal treatment. study sample 123 patients with confirmed COVID-19 was classified based on degree severity: 50 mild severity, 34 moderate 39 severe critical who were subjected complete blood count lymphocyte subsets (CD3, CD4, CD8) Flowcytometry. There significant number CD 3 (p=0.000), CD4 CD8...

Purpose: To identify the anti-inflammatory components of beta-beta (Lunasia amara Blanco.) wood.Methods: The wood material was extracted with 96 % ethanol and fractionated dichloromethane using a liquid-liquid continuous extraction (LLCE). fractions were subjected to silica gel column chromatography. Components extracts identified by thin layer chromatography (TLC) scanner UV-visible spectroscopy, scopoletin as standard.Results: TLC results for Lunasia extract showed same spot standard...

Mengkudu fruit contains scopoletin and temulawa k rhizome curcumin have been observed because they strong antioxidant activity were used traditionally as antidiabetic. This research aimed to evaluate effect of antihyperglycemic pancreas protection juice combination mengkudu (MFJ) (TRJ) on diabetes rats which inducted with streptozotocin (STZ). Rats grouped into 7 groups, each group consisting 5 rats. Each was treated accordingly for 28 days except a normal taken blood from the plexus...

Pediculosis capitis is a skin or head hair infestation caused by Pediculus humanus var. Capitis. mainly affects young children and some factors help spread capitis, namely socio-economic, level of knowledge, poor hygiene conditions, the density dwellings such as boarding schools. This research method quantitative study with an observational analytic cross-sectional approach, assessing personal then relating it to incidence capitis. Data collection was carried out in August 2018. The...

Lack of dental care will be resulted in the increased colonies C. albicans if was not ordinary condition that can cause denture stomatitis. is common wearer and found as many 86% patients with Cashew bark contains tannins, gallic acid anacardic acid, phenolic compounds which are responsible for antifungal activity against albicans. This research consisted determination total compound by Folin Ciocalteu method, test acrylic resin plate. Acrylic plate immersed a suspension 24 hours, rinsed...

Immunomodulator has been used as one of the attention to develop herbal medicine. Jahe is medicine which usually heal various diseases. Emprit  is local name in Indonesia. The aim this research was investigate effect pungent principle containing extract emprit rhizome on macrophage activity compared by levamisol and Echinacea extract. Extraction done 70%v/v ethanol. concentrations were 5 mg/kg B.W; 25 100 B.W. CMC Na 1,5%w/v solvent control. Levamisol 2,5 B.W 10 positive ability  measured...

HIV/AIDS (Human Immunodeficiency Virus / Acquired Immune Deficiency Syndrome) has long been an issue along with the continued attention of various circles around world, especially health sector. The purpose this study was to determine characteristics relationship workers in centers stigma on people living HIV Talun Blitar regency. This used a cross-sectional design population 36 respondents that all research sample. Collecting data using questionnaires. Analysis statistical test Pearson and...

Background: Tinea corporis or also known as ringworm, is a superfisial fungal infection of The skin that can effect people all ages and genders. Hyperglycemia risk factor for tinea in diabetic patients (especially type 2 diabetes mellitus), so glycemic control plays an important role prevention management this condition. This study aims to determine the relations between hyperglycemia mellitus at Graha Hermine Hospital Batam 2021. Methods: observational analytic with cross-sectional design...

Views Icon Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Twitter Facebook Reddit LinkedIn Tools Reprints and Permissions Cite Search Site Citation Hidayat Hidayat, Sudarsono Sudarsono, Mariyo Julis Hallenio; Designing of smart monitoring fuel flow meter measurement. AIP Conf. Proc. 3 May 2024; 2915 (1): 020021. https://doi.org/10.1063/5.0194023 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex...

Background: Knee osteoarthritis is a multifactorial degenerative joint disease associated with damage to the cartilage of knee joint. Risk factors that play role are increasing age, body mass index. OA affects ³ 45 years age. This study aims determine relationship between age and index incidence in women at Santa Elisabeth Hospital Lubuk Baja Batam City. Methods: research type quantitative research. method analytic observation cross sectional approach conducted City for period 2022. Data...

AISI 1037 and 304 steels are widely used across various industrial sectors, including manufacturing, transportation, petrochemical, automotive industries. In this study, the effect of preheating on toughness dissimilar welded joints between 304, joined by Shielded Metal Arc Welding (SMAW) using E309-16 electrodes, was investigated. The process performed prior to welding, its influence joint's assessed through impact testing. Additionally, hardness profile joint evaluated...

This study explores the effect of preheating on toughness dissimilar welded joints between AISI 1037 and 304 steels, using Shielded Metal Arc Welding (SMAW) E309-16 electrodes. The innovation this approach lies in assessing how temperatures influence mechanical properties such welds. Preheating ranged from 150 °C to 300 °C, with impact testing revealing a notable increase toughness, 6.01 Joules at 19.57 °C. Hardness tests indicated maximum hardness 313 VHN fusion zone minimum 185 area....

Composite is a new type of material which the result engineering, consisting two or more materials, with properties each being different from other both in terms chemical and physical properties. The aim this research to determine tensile flexural strength values pineapple leaf fiber composites cross-ply laminate configuration arrangement angles [0, 90°, 0°], [45˚, -45˚, 45˚] [ 30°, -30°, 30°]. This uses directions [30˚, -30 ˚, 30 ˚] uses. composite was made mold measuring P = 190 mm, L 90...