Abstract Sample particle size is an important parameter in the solid–liquid extraction system of natural products for obtaining their bioactive compounds. This study evaluates effect sample on phytochemical composition and antioxidant activity brown macroalgae Sargassum cristaefolium . The crude ethanol extract was extracted from dried powders S.cristeafolium with various sizes (> 4000 µm, > 250 125 45 < µm). ethanolic extracts S.cristaefolium were analysed Total Phenolic Content...

Exploration of plant combinations could be an alternative approach for diabetes treatment. The aim this study is to evaluate the hypoglycemic effect combination A. indica and G. procumbens ethanolic extracts in alloxan-induced diabetic rats.Powder leaves were macerated with ethanol 70%. Determination rutin quercetin performed by TLC-densitometry. Hyperglycemia rats was induced intraperitoneal injection alloxan monohydrate at a single dose 150 mg/kgBW. treated 3 dosage variation 15 days....

Nutritional supplementation with fish oil or ω‐3 (n‐3) polyunsaturated fatty acids (PUFAs) has potential benefits for skin inflammation. Although the differential metabolism of main n‐3PUFA eicosapentaenoic acid (EPA) and docosahexaenoic (DHA) could lead to distinct activities, there are no clinical studies comparing their relative efficacy in human skin. Following a 10‐wk oral healthy volunteers using mass spectrometry‐based lipidomics, we found that mainly affected epidermal mediator...

Cancer is a disease characterized by uncontrolled abnormal cell growth, originating from cancer stem cells. These cells form side population with stemness properties similar to normal cells, have high tumorigenicity, and contribute the development of cancer. Among all cases, breast one causes death in women worldwide, estimated reach 28% new cancers. The application genetic engineering techniques CRISPR / Cas9 which can be used as an alternative choice optimizing therapy. This literature...

Ultraviolet radiation (UVR) which could induce skin damage and disease is a growing concern due to the increase in global warming. Brown macroalgae Sargassum cristaefolium has been recognized exhibit UV protective activities. However, mechanism of its photoprotective activity remains unclear. The purpose this study investigate potential S. cristaefolium's against radiation. Phytochemical analyses revealed valuable bioactive compounds SCE, such as fucoxanthin widely known an anti-inflammatory...

Indonesia has high biodiversity of algae that are under-utilised due to limitations in the processing techniques. Here, we observed effect two different extraction methods (cold maceration and ultrasonic-assisted (UAE)) on multiple variables Indonesian brown ethanol extracts (Sargassum polycystum, Sargassum cristaefolium, aquifolium Turbinaria ornata). The included metabolites screening by untargeted metabolomics liquid chromatography-high-resolution mass spectrometry (LC-HRMS), observation...

The brown macroalgae

Many studies have evidenced the negative effects of synthetic fertilizers toward environment and also crop products itself. Hence, improvement organic is necessary to resolve this problem. Seaweeds or marine macroalgae are considered be an excellent natural resource in different aspects agricultural fields. Brown Turbinaria murayana (TM) often found Indonesian coastal areas with high bioavailability throughout year. This study evaluated potentials TM as biofertilizer tomato plants...

Abstract The demand for agricultural commodities increases from year to year, so farmers also have increase the production of products. Farmers can yields through excessive use inorganic fertilizers. This causes many problems environment, it is required reduce fertilizers in land. study aimed determine effect a combination organic and on growth yield rice. research was carried out screen house Jatisela, Gunung Sari Subdistrict, Lombok June October 2020. three treatments used this were P0 N0...

Abstract The coastal areas of Lombok has very high diversity macroalgae which are largely unexplored. Among them the brown Sargassum species well known for their biological potentials. In this study, we aim to evaluate 4 species, S.cristaefolium, S. crassifolium, polycystum, and aquifolium antioxidant potential found west Aare Lombok, Indonesia. To determine capacity macroalgal extracts, 2,2-diphenyl-1-picrylhydrazyl (DPPH) as total phenolic content (TPC) were measured. Extracts have active...

The red macroalga Gelidium latifolium is widely distributed in the coastal areas of Indonesia. However, current knowledge on its potential biological activities still limited. In this study, we investigated bioactive compounds ethanol extract (GLE), and cytotoxic effects against murine B16-F10 melanoma cell line. GLE shows high total phenolic content (107.06 ± 17.42 mg GAE/g) flavonoid (151.77 3.45 QE/g), which potentially contribute to antioxidant activity (DPPH = 650.42 2.01 µg/mL; ABTS...

Abstract The use of inorganic fertilizers in rice production system Indonesia, increases to an excessive level application, which was 300 kg urea, 100 TSP, and KCl per hectare, respectively. This application cost production, reduces soil fertility, farmers income, harm environment. article reports the effect Lombok brown algae extracts on growth yield plants grown media containing several doses fertilizers. algaes, such as Sargassum crassifolium, cristaefolium, aquifolium, Turbinaria...

Renggak (Amomum dealbatum Roxb.) is a species from the genus Amomum widely spread in Lombok. Traditionally, Roxb. (renggak) an antiseptic to treat rheumatism and arthritis. However, there was limited report of its phytochemical contents biological activity This study preliminary research that aims determine content leaf decoction ethanolic extract. For this study, we used two different extraction methods. The fully powdered plant for successive cold process maceration methods 800 g, ethanols...

There are seven species of Gyrinops and two Aquilaria (Thymelaeaceae), which distributed in Eastern Indonesia at the east Wallace line. The anatomical character paradermal tissue, midrib petiole were important characteristics possessed by plants that can be used as data for identification. purpose this article was to study leaf morphoanatomical variation Region East Line. specimen research collection Agarwood Study Center, Universitas Mataram, Indonesia. slide made with whole-mount method...

Abstract Abstract.Collagen is a fibrous protein that has recently gained high attention from the pharmaceutical industry due to its benefits on skin. Collagen can be isolated various resources including marine sponges. Marine sponges are found in large amount Indonesia and not been widely explored for pharmacology benefits. Here we isolate collagen sponge Stylissa flabelliformis North Lombok coast. The isolation of was performed followed by total content analysis using modified Bradford...

Abstract Excessive use of inorganic fertilizers in the production horticultural crops, increases costs, decreases soil fertility and damages environment. This article reports growth yield tomato plants grown media containing several doses sprayed with Lombok brown algae extract. Tomato are at a dose 0, 50% or 100%. Then, each treatment plant was 10% extract once week during vegetative growth. The results showed that had same effect on NPK absorption, plants. However, extracts absorption...

Corona Virus Disease 2019 (COVID-19) is a new strain of coronavirus called SARS-CoV-2, which was identified in Wuhan, China, December 2019. The rapid transmission COVID-19 from human to forced researchers find potent drug by setting aside the time-consuming traditional method development. molecular docking approach one reliable screening compound chemical or finding Indonesian herbal plants. present study aimed assess potency compounds five medicinal plants as potential inhibitors PLpro and...

Abstract Abstract.The prevalence of skin cancer continues to increase from year year. Skin mainly caused bymelanin accumulation on the surface (hyperpigmentation) or excessive melanogenesisoccurs. The brown macroalgae S. crassifolium is one marine natural resources which abundant in Lombok, Indonesia coastal areas. However, information regarding its potential bioactive activities remains limited. This study aims evaluate effective extraction solvent for gaining optimum compounds with...

Vitamin C is a compound that cannot be formed by the body itself. needed to regulate metabolic processes and normal functions. Lack of vitamin can cause decrease in immune system. During pandemic, improve system prevent fight disease infections. The pandemic has caused an increase need price supplements market. Fulfilling body’s needs use alternatives such as Moringa leaves green spinach. This study aims determine levels spinach with variations temperature concentration. Analysis was carried...

COVID-19 patients with comorbid DM face more severe outcomes, indicating that hyperglycemic conditions exacerbate SARS-CoV-2 infection. Negative side effects from existing hyperglycemia treatments have urged the need for safer compounds. Therefore, sourcing potential compounds marine resources becomes a new approach. Algal lipids are known to possess beneficial activities human health. However, due limitations in analyzing large amounts of anti-hyperglycemic and anti-COVID-19-related...

Secara alami gaharu diproduksi oleh pohon yang mengalami luka atau terinfeksi jamur. Agar sehat dapat menghasilkan gubal harus ada perlakuan khusus: seperti perlukaan, memasukan bakteri jamur penyebab agensia kimia. Tujuan kegiatan ini memberi pengetahuan dan ketrampilan kepada masyarakat memiliki ketimunan (Gyrinops versteegii) siap suntik di Desa Puyung, Kecamatan Jonggat, Lombok Tengah, dalam menginokulasi, memanen, mengolah pasca panen gaharu. Pelaksanana “Pengabdian Pada Masyarakat”...

Perguruan tinggi dalam menjalankan aktivitas profesional dibidang pendidikan tidak terlepas dari peran dosen dan tenaga pendidik. Program Studi Farmasi Universitas Mataram merupakan salah satu Tinggi Negeri yang bersinergi meningkatkan mutu akademika. Dalam rangka melaksanakan fungsi profesional, diperlukan strategi untuk kualitas kerja Kegiatan ini diselenggarakan dengan tujuan serta kekompakan pendidik memberikan training melalui games secara berkelompok. telah terselenggara berjalan baik...

Purple leaf (Graptophyllum pictum L. Griff) is a plant that has antibacterial, antioxidant, anti-inflammatory and antidiarrheal benefits. Flavonoids, alkaloids, steroids, saponins, tannins are some of the secondary metabolites found in leaves have antibacterial properties. This study aims to determine content phytochemical compounds purple twig extract. The method used screening identify flavonoid, alkaloid, saponin, tannin, steroid terpenoid compounds. results showed extract contained...