- Plant Virus Research Studies
- Plant Parasitism and Resistance
- Plant Molecular Biology Research
- Plant-Microbe Interactions and Immunity
- Bacteriophages and microbial interactions
- Plant nutrient uptake and metabolism
- Evolution and Genetic Dynamics
- RNA modifications and cancer
- Plant Reproductive Biology
- Marine Ecology and Invasive Species
- Diabetes and associated disorders
- Marine and coastal plant biology
- Developmental Biology and Gene Regulation
- RNA Research and Splicing
- Plant and Fungal Interactions Research
Max Planck Institute for Developmental Biology
2024
Max Planck Institute for Biology
2024
Center for Excellence in Molecular Plant Sciences
2017-2022
Chinese Academy of Sciences
2017-2022
University of Chinese Academy of Sciences
2017-2020
RNA interference (RNAi) in plants can move from cell to cell, allowing for systemic spread of an antiviral immune response. How this cell-to-cell silencing is regulated currently unknown. Here, we describe that the C4 protein Tomato yellow leaf curl virus inhibit intercellular RNAi. Using viral as a probe, have identified receptor-like kinase (RLK) BARELY ANY MERISTEM 1 (BAM1) positive regulator movement RNAi, and determined BAM1 its closest homolog, BAM2, play redundant role process....
In plants, establishment of de novo DNA methylation is regulated by the RNA-directed (RdDM) pathway. RdDM machinery known to concentrate in Cajal body, but biological significance this localization has remained elusive. Here, we show that antiviral Tomato yellow leaf curl virus (TYLCV) genome requires body Nicotiana benthamiana cells. Methylation viral countered a virus-encoded protein, V2, which interacts with central component AGO4, interfering its binding DNA; V2-AGO4 interaction...
Drought causes important declines in crop yield, negatively impacting plant growth, physiology and reproduction. Plants have adopted a wide range of strategies to confront the negative effects drought, including increasing water uptake by optimizing root system, closing stomata limit loss caused transpiration, accumulating osmoprotectants, or producing hormone abscisic acid (ABA). This intricate scenario makes drought resistance highly complex trait, with polygenic nature, low heritability,...
Viruses reshape the intracellular environment of their hosts, largely through protein-protein interactions, to co-opt processes necessary for viral infection and interference with antiviral defences. Due genome size constraints concomitant limited coding capacity viruses, proteins are generally multifunctional have evolved target diverse host proteins. Inference virus-host interaction network can be instrumental understanding how viruses manipulate machinery re-wiring specific pathways...
Viruses are intracellular parasites with a nucleic acid genome and proteinaceous capsid. Viral capsids formed of at least one virus-encoded capsid protein (CP), which is often multifunctional, playing additional non-structural roles during the infection cycle. In animal viruses, there examples differential localization CPs associated to progression and/or enabled by other viral proteins; these changes in distribution may ultimately regulate involvement proteins different functions. this...
Viruses are strict intracellular parasites that rely on the proteins encoded in their genomes for effective manipulation of infected cell ultimately enables a successful infection. Viral have to be produced during invasion and takeover sufficient amounts timely manner. Silencing suppressor evolved by plant viruses can boost production viral proteins; although, additional mechanisms regulation protein likely exist. The strongest silencing geminivirus tomato yellow leaf curl virus (TYLCV) is...
ABSTRACT In plants, establishment of de novo DNA methylation is regulated by the RNA-directed (RdDM) pathway. RdDM machinery known to concentrate in Cajal body, but biological significance this localization has remained elusive. Here, we show that anti-viral Tomato yellow leaf curl virus (TYLCV) genome occurs specifically body Nicotiana benthamiana cells. Methylation viral countered a virus-encoded protein, V2, which interacts with central component AGO4, interfering its binding DNA; V2-AGO4...
In plants, the RNA-directed DNA methylation (RdDM) pathway plays a major role in establishing methylation. At least some components of RdDM machinery, including central component AGO4, are known to concentrate subnuclear compartment called Cajal body model plant Arabidopsis thaliana. The molecular underpinnings localization, however, have remained elusive so far. Here, we found that AGO4 (AtAGO4) fused GFP does not present its typical when transiently expressed Nicotiana benthamiana....