A5101644549- Magnesium Alloys: Properties and Applications
- Bone Tissue Engineering Materials
- Sexual function and dysfunction studies
- Urinary Bladder and Prostate Research
- Lipid metabolism and disorders
- Aluminum Alloys Composites Properties
- Corrosion Behavior and Inhibition
- Cancer-related molecular mechanisms research
- Pelvic floor disorders treatments
- Neurological Disorders and Treatments
- Orthopaedic implants and arthroplasty
- Liver Disease Diagnosis and Treatment
- Hormonal and reproductive studies
- Endometriosis Research and Treatment
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Hormonal Regulation and Hypertension
- Neuroscience and Neuropharmacology Research
- Titanium Alloys Microstructure and Properties
- Neonatal and fetal brain pathology
- Contact Mechanics and Variational Inequalities
- Neurological Disease Mechanisms and Treatments
- Neonatal Health and Biochemistry
- Adrenal and Paraganglionic Tumors
- Parathyroid Disorders and Treatments
- Medication Adherence and Compliance
Tongji Hospital
2019-2025
Huazhong University of Science and Technology
2012-2025
National Clinical Research Center for Digestive Diseases
2023-2025
Zhengzhou University
2022-2025
Zhengzhou University of Light Industry
2025
University of Kansas
2014
Recent studies have demonstrated that insulin plays important roles in the brain, including regulation of glucose metabolism and modulation learning memory. We found dysregulation brain signaling both Alzheimer's disease (AD
Abstract Inhibition of immunocyte infiltration and activation has been suggested to effectively ameliorate nonalcoholic steatohepatitis (NASH). Paired immunoglobulin-like receptor B (PirB) its human ortholog receptor, leukocyte (LILRB2), are immune-inhibitory receptors. However, their role in NASH pathogenesis is still unclear. Here, we demonstrate that PirB/LILRB2 regulates the migration macrophages during by binding with ligand angiopoietin-like protein 8 (ANGPTL8). Hepatocyte-specific...
Current materials comprising suture anchors used to reconstruct ligament-bone junctions still have limitation in biocompatibility, degradability or mechanical properties. Magnesium alloys are potential bone implant materials, and Mg2+ has been shown promote healing. Here, we Mg-2 wt.% Zn-0.5 Y-1 Nd-0.5 Zr (ZE21C) alloy Ti6Al4V (TC4) prepare the patellar ligament-tibia SD rats. We studied degradation behavior of ZE21C anchor via vitro vivo experiments assessed its reparative effect on...
Abstract Biodegradable porous magnesium alloy (pMg) scaffolds hold significant potential for repair of bone defects owing to favorable mechanical properties and biocompatibility. However, a critical challenge remains in matching the degradation rate pMg with pace regeneration. Low-intensity pulsed ultrasound (LIPUS) has emerged as promising therapeutic strategy enhance repair. In this study, femoral Sprague–Dawley rats were implanted scaffolds, LIPUS was applied defect sites...
Telomere length and telomere shortening rate (TSR) are accepted indicators of aging in cross-sectional population studies. This study aimed to investigate the potential influence common antidiabetic agents on TSR patients with type 2 diabetes mellitus (T2DM). Leukocyte was measured through terminal restriction fragment analysis, calculated 388 T2DM patients. Depending whether or not they received medication, were first divided into a treatment group nontreatment group. Treated further...
Magnesium (Mg) is abundant in humans. Studies have shown that Mg2+ significantly affects physiological processes such as osteogenesis, osteoblast adhesion and motility, immunomodulation, angiogenesis. Mg-based alloy porous scaffolds attracted increasing attention because of their degradability mechanical properties. Hence, wire-cut EDM was used to fabricate scaffolds. In addition, fluoride treatment afforded an MgF2 coating, racemic polylactic acid PDLLA the carrier rhBMP-2, which evenly...
Erectile dysfunction (ED) is common but usually underdiagnosed in diabetics. The correlation between different vascular lesions and ED diabetics without clinical cardiovascular symptoms unknown. aim was to explore the association risks Chinese type 2 diabetic men lacking performance.Erectile function of patients with diabetes assessed by 5-item International Index Function (IIEF-5) questionnaire. data characteristics at carotid lower limb sites Doppler ultrasound were collected evaluate...
Magnesium is abundant in humans. Studies have shown that Mg2+ significantly affects physiological processes such as osteogenesis, osteoblast adhesion and motility, immunomodulation, angiogenesis. Porous magnesium alloy scaffolds attracted increasing attention because of their degradability mechanical properties. Hence, wire-cut EDM was used to fabricate a porous ZE21C scaffold. In addition, fluoride treatment afforded an MgF2 coating, racemic polylactic acid PDLLA the carrier rhBMP-2, which...
Background: An antidiabetic medication regimen is crucial for maintaining glycemic control. Type 2 diabetes mellitus (T2DM) and cognitive dysfunction have a bidirectional relationship. This study aims to explore the impact that adjusting regimens has on adherence, control, function in patients with T2DM mild impairment (MCI). Methods: an observational cross-sectional analysis includes 364 consecutive inpatients T2DM. Clinical data were collected, adherence was assessed using Medication...
Abstract Inhibition of immunocyte infiltration and activation has been proven to effectively ameliorate hepatic inflammation fibrosis in nonalcoholic steatohepatitis (NASH). Paired immunoglobulin-like receptor B (PirB) its human orthologue receptor, leukocyte (LILRB2), are immune-inhibitory receptors with unknown roles NASH. Here, we demonstrate that PirB/LILRB2 regulates the migration macrophages NASH pathogenesis fibrogenesis by binding NASH-associated ligand angiopoietin-like protein 8...
Current materials comprising suture anchors used to reconstruct ligament-bone junctions still have limited mechanical properties, degradability, and biocompatibility. Magnesium alloys are potential bone implant materials, Mg2+ has been shown promote healing. Here, we an Mg-2wt% Zn-0.5wt% Y-0.5wt% Nd-0.4wt% Zr (ZE21C) a Ti6AL4V (TC4) alloy prepare the patellar ligament proximal tibia in SD rats. We studied degradation behavior of ZE21C anchor via vitro vivo experiments assessed its reparative...