Xiaoli Shi

ORCID: 0000-0002-2904-1784
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About
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Research Areas
  • Aquatic Ecosystems and Phytoplankton Dynamics
  • Marine and coastal ecosystems
  • Microbial Community Ecology and Physiology
  • Wheat and Barley Genetics and Pathology
  • Biocrusts and Microbial Ecology
  • Chromosomal and Genetic Variations
  • Protist diversity and phylogeny
  • Aquaculture Nutrition and Growth
  • Genomics and Phylogenetic Studies
  • Plant Disease Resistance and Genetics
  • Genetic Mapping and Diversity in Plants and Animals
  • Aquaculture disease management and microbiota
  • Marine Toxins and Detection Methods
  • Force Microscopy Techniques and Applications
  • COVID-19 Clinical Research Studies
  • Plant Molecular Biology Research
  • Invertebrate Immune Response Mechanisms
  • Genetics and Plant Breeding
  • Plant Reproductive Biology
  • Environmental Toxicology and Ecotoxicology
  • Circadian rhythm and melatonin
  • Aquatic Ecosystems and Biodiversity
  • Cellular Mechanics and Interactions
  • Cancer-related molecular mechanisms research
  • Protein Interaction Studies and Fluorescence Analysis

Huazhong University of Science and Technology
2020-2025

Tongji Hospital
2020-2025

National Clinical Research Center for Digestive Diseases
2021-2025

Shenzhen Children's Hospital
2023-2025

Nanjing Institute of Geography and Limnology
2015-2024

Chinese Academy of Sciences
2015-2024

Institute of Genetics and Developmental Biology
2017-2024

Jinzhong University
2024

Hebei Normal University
2014-2024

Ningde Normal University
2021-2024

We report improved whole-genome shotgun sequences for the genomes of indica and japonica rice, both with multimegabase contiguity, or almost 1,000-fold improvement over drafts 2002. Tested against a nonredundant collection 19,079 full-length cDNAs, 97.7% genes are aligned, without fragmentation, to mapped super-scaffolds one other genome. introduce gene identification procedure plants that does not rely on similarity known remove erroneous predictions resulting from transposable elements....

10.1371/journal.pbio.0030038 article EN cc-by PLoS Biology 2005-01-21

Objective This study explores the clinical characteristics of patients with diabetes severe covid-19, and association survival duration in covid-19. Research design methods In this single-center, retrospective, observational study, laboratory 193 covid-19 were collected. 48 had diabetes, 145 (ie, controls) did not have diabetes. A case was defined as including at least one following criteria: (1) Respiratory rate >30/min. (2) Oxygen saturation ≤93%. (3) PaO 2 /FiO ≤300 mm Hg. (4)...

10.1136/bmjdrc-2020-001343 article EN cc-by-nc BMJ Open Diabetes Research & Care 2020-04-01

We have investigated the capability of single-walled carbon nanotubes (SWNTs) to penetrate cell wall and membrane intact plant cells. Confocal fluorescence images revealed cellular uptake both SWNT/fluorescein isothiocyanate SWNT/DNA conjugates, demonstrating that SWNTs also hold great promise as nanotransporters for walled Moreover, result suggested could deliver different cargoes into organelles.

10.1021/nl803083u article EN Nano Letters 2009-02-03

Triticum urartu (diploid, AA) is the progenitor of A subgenome tetraploid (Triticum turgidum, AABB) and hexaploid aestivum, AABBDD) wheat1,2. Genomic studies T. have been useful for investigating structure, function evolution polyploid wheat genomes. Here we report generation a high-quality genome sequence by combining bacterial artificial chromosome (BAC)-by-BAC sequencing, single molecule real-time whole-genome shotgun sequencing3, linked reads optical mapping4,5. We assembled seven...

10.1038/s41586-018-0108-0 article EN cc-by Nature 2018-05-01

• Large-scale duplication events have been recently uncovered in the rice genome, but different interpretations were proposed regarding extent of duplications. Through analysing 370 Mb genome sequences assembled into 12 chromosomes Oryza sativa subspecies indica, we detected 10 duplicated blocks on all that contained 47% total predicted genes. Based phylogenetic analysis, inferred this was a result occurred c. 70 million years ago, supporting polyploidy origin genome. In addition, segmental...

10.1111/j.1469-8137.2004.01293.x article EN New Phytologist 2005-01-14

Abstract Background The triglyceride and glucose index (TyG) has been proposed as a marker of insulin resistance. This study aims to evaluate the association TyG with severity mortality coronavirus disease 2019 (COVID-19). Methods included cohort 151 patients COVID-19 admitted in tertiary teaching hospital Wuhan. Regression models were used investigate between COVID-19. Results In this cohort, 39 (25.8%) had diabetes, 62 (41.1%) severe cases, while 33 (22.0%) died hospital. levels...

10.1186/s12933-020-01035-2 article EN cc-by Cardiovascular Diabetology 2020-05-11

To investigate the changes in morphology and polysaccharide content of Microcystis aeruginosa (Kütz.) Kütz. during flagellate grazing, cultures M. were exposed to grazing Ochromonas sp. for a period 9 d under controlled laboratory conditions. responded actively formed colonies, most which made up several or dozens cells, suggesting that may be one biotic factors responsible colony formation . When colonies formed, cell surface ultrastructure changed, layer on wall became thicker. This change...

10.1111/j.1529-8817.2008.00502.x article EN Journal of Phycology 2008-05-07

In this work, we have developed new aptamer probes for non-small cell lung cancer (NSCLC) by directing the selection process against living cells of adenocarcinoma, most common subtype NSCLC. A panel single-stranded DNA (ssDNA) aptamers were generated and evaluated adenocarcinoma recognition. The bound to with dissociation constants in nanomolar range binding selected significantly stronger than other cancerous as well types cells. Moreover, application clinical tissue section samples showed...

10.1039/b904476k article EN The Analyst 2009-01-01

Intercellular interactions between cardiomyocytes (CMs) and cardiofibroblasts (FBs) are important in the physiological pathophysiological heart. Understanding such is for developing effective heart disease therapies. However, until recently, little has been known about these interactions. We aimed to investigate structural functional connections CMs FBs that distinct from gap junctions. By membrane dye staining, we observed long, thin nanotubular structures containing actin microtubules...

10.1093/cvr/cvr189 article EN Cardiovascular Research 2011-06-30

The genetic distance between hybridizing parents affects heterosis; however, the mechanisms for this remain unclear. Here we report that correlates with natural variation and epigenetic regulation of circadian clock-mediated stress responses. In intraspecific hybrids Arabidopsis thaliana, genome-wide expression many biotic abiotic stress-responsive genes is diurnally repressed biomass heterosis quantitative trait loci. Expression differences selected among diverse ecotypes are predictive in...

10.1038/ncomms8453 article EN cc-by Nature Communications 2015-07-08

Cholangiocarcinoma is a highly aggressive malignant tumor disease with the increasing incidence and mortality. It's urgent to identify specific biomarkers for cholangiocarcinoma treatment diagnosis. Recent studies have noted importance of lncRNAs in cancer following downstream mechanism miRNAs network has been hotspot. This work aimed discover role lncRNA HCG18 its possible progression. Initially, through bioinformatics tools, we observed abnormal expression cholangiocarcinoma. In vitro...

10.1038/s41417-022-00500-2 article EN cc-by Cancer Gene Therapy 2023-02-28
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