A5021873858- Heart Failure Treatment and Management
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Hemodynamic Monitoring and Therapy
- Acute Myocardial Infarction Research
- Cardiac pacing and defibrillation studies
- Dialysis and Renal Disease Management
- Cardiac electrophysiology and arrhythmias
- Cardiac Structural Anomalies and Repair
- Electrolyte and hormonal disorders
- Potassium and Related Disorders
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Cardiac Valve Diseases and Treatments
- Mechanical Circulatory Support Devices
- Erythropoietin and Anemia Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Advanced MRI Techniques and Applications
- Blood Pressure and Hypertension Studies
- Inflammatory Biomarkers in Disease Prognosis
- Pulmonary Hypertension Research and Treatments
- Atrial Fibrillation Management and Outcomes
- Reproductive tract infections research
- Hormonal Regulation and Hypertension
- Diabetes Treatment and Management
- Urinary Tract Infections Management
Mayo Clinic in Arizona
2016-2025
Mayo Clinic
2015-2024
Mayo Clinic in Florida
2009-2023
Stamford Hospital
2023
WinnMed
2013-2022
Lung Institute
2016-2021
Northwestern University
2018
Johns Hopkins University
2018
Medical University of South Carolina
2018
Lawson Health Research Institute
2010-2013
Background: Survival is poor in patients with acute myocardial infarction (MI) who also have severe renal disease. Less known about the outcome of MI mild to moderate insufficiency. Objective: To compare outcomes after varying levels disease and without failure. Design: Retrospective cohort study. Setting: Academic medical center. Patients: 3106 total admitted end-stage (n = 44), insufficiency (creatinine clearance < 0.59 mL/s [<35 mL/min]) 391), dysfunction ≥ mL/min] but ≤ 0.84 [≤ 50 491),...
Background: Functional tricuspid regurgitation (FTR) is common in heart failure with reduced ejection fraction and mostly consequent to pulmonary hypertension. However, the intrinsic clinical implications of FTR are not fully understood. Methods: The cohort all Mayo Clinic patients from 2003 2011 diagnosed stage B-C fraction<50%, grading systolic artery pressure estimation by Doppler echocardiography was identified outcomes were analyzed. Patients pacemakers/defibrillators, organic valve...
Volume regulation, assessment, and management remain basic issues in patients with heart failure. The discussion presented here is directed at opening a reassessment of the pathophysiology congestion congestive failure methods by which we determine volume overload status. Peer-reviewed historical contemporary literatures are reviewed. fluid primary for chronic complex, simple concept intravascular accumulation not adequate. dynamics interstitial compartment interactions redistribution from...
We conducted experiments to determine (1) tissue, blood, and urine levels of adenosine produced by the ischemic kidney under conditions renal artery occlusion, (2) site(s) production release kidney. Concentrations adenosine, inosine, hypoxanthine in dog were found increase after 2 minutes occlusion as concentrations these metabolites tissue 10 occlusion. Renal venous plasma inosine also elevated 3 arterial In modified stop-flow experiments, appeared a peak that corresponded most closely with...
Background— Cardiac troponin T (cTnT) and B-type natriuretic peptide (BNP) have been used to estimate prognosis in heart failure; however, most studies evaluated decompensated patients with single measurements. To determine if there are advantages serial measurements, we stable chronic failure every 3 months for 2 years. Methods Results— A cohort of 190 New York Heart Association class III–IV was prospectively enrolled from June 2001 January 2004. Primary end points were death, cardiac...
This study sought to quantitate total blood volume (TBV) in patients hospitalized for decompensated chronic heart failure (DCHF) and determine the extent of overload, magnitude distribution body water changes following diuretic therapy.The accurate assessment management overload with DCHF remains problematic.TBV was measured by a radiolabeled-albumin dilution technique intravascular volume, pre-to-post-diuretic therapy, evaluated at hospital admission discharge. Change weight relation...
Background— Multiple B-type natriuretic peptide (BNP) fragments circulate in patients with heart failure (HF) but the types and relative quantities, particularly relation to bioactive BNP 1-32, remain poorly defined. The purpose of study was relate clinically available values quantitative information on concentration pre-secretion post-processed detected by mass spectrometry. Methods Results— Seventy Class I–IV were prospectively enrolled blood drawn into tubes containing a preservative...
Patients with combined post- and precapillary pulmonary hypertension due to left heart disease have a worse prognosis compared isolated postcapillary. However, it remains unclear whether increased mortality in is simply result of higher total right ventricular load. Pulmonary effective arterial elastance (Ea) measure afterload, reflecting both resistive pulsatile components. We aimed test Ea discriminates survivors from nonsurvivors patients if does so better than other hemodynamic...
The adverse prognostic significance of biomarker elevations after percutaneous coronary intervention (PCI) is well established. However, often baseline troponin values are not included in the analysis or sensitive criteria employed. Accordingly, we assessed timing and magnitude post-PCI T (cTnT) levels their relationships to outcomes patients with without pre-PCI cTnT using a assay cut-off values.cTnT was measured at (pre-PCI), 8 16 h 2352 patients. A elevation defined as > =0.03 ng/mL. No...
<h3>Background</h3> Disease progression in heart failure (HF) reflects derangements neurohormonal systems, and biomarkers of these systems can help to establish the diagnosis assess prognosis. Serial measurements precursor peptides natriuretic vasopressin (midregional proatrial peptide (MR-proANP) C-terminal provasopressin (copeptin), respectively) should add incremental value risk stratification ambulatory patients with HF. <h3>Methods results</h3> A cohort 187 class III–IV HF was...
Co-existence of obstructive sleep apnea (OSA) and chronic pulmonary disease (COPD) is referred to as overlap syndrome. Overlap patients have greater degree hypoxia hypertension than with OSA or COPD alone. Studies showed that elderly alone do not increased risk atrial fibrillation (AF) but it known if higher AF. To determine whether syndrome an