A5101586270- Functional Brain Connectivity Studies
- Migraine and Headache Studies
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Cancer-related molecular mechanisms research
- Advanced Neuroimaging Techniques and Applications
- Ferroptosis and cancer prognosis
- Trigeminal Neuralgia and Treatments
- Olfactory and Sensory Function Studies
- Intracerebral and Subarachnoid Hemorrhage Research
- MicroRNA in disease regulation
- Photonic and Optical Devices
- Psychosomatic Disorders and Their Treatments
- Traditional Chinese Medicine Studies
- Cardiovascular Health and Disease Prevention
- Venous Thromboembolism Diagnosis and Management
- Advanced Fiber Optic Sensors
- Photonic Crystal and Fiber Optics
- Receptor Mechanisms and Signaling
- Atrial Fibrillation Management and Outcomes
- Medicinal Plants and Neuroprotection
- Neuroscience and Neuropharmacology Research
- Neuropeptides and Animal Physiology
- Bone Metabolism and Diseases
- RNA modifications and cancer
First Affiliated Hospital of Kunming Medical University
2025
Kunming Medical University
2025
Shihezi University
2025
Fuzhou Maternity and Child Health Care Hospital
2025
Shanghai Ninth People's Hospital
2014-2024
Shanghai Jiao Tong University
2014-2024
Shandong Provincial Hospital
2024
Shandong First Medical University
2024
Huazhong University of Science and Technology
2020-2024
Capital Medical University
2009-2024
Lung cancer is the leading cause of cancer-related death worldwide. The sex differences in occurrence and fatality rates non-small cell lung (NSCLC), along with its association estrogen dependence, suggest that receptors (ERs) contribute to development NSCLC. However, influence G protein-coupled receptor (GPER1) on NSCLC remains be determined. Escape from ferroptosis one hallmarks tumor discovered recent years. In this context, present study evaluated whether GPER1 promotes progression by...
Abstract Background and objective Colon cancer is occurring at an increasing rate ginger ( Zingiber officinale ) , as a commonly used herbal medicine, has been suggested potential agent for colon cancer. This study was aimed to identify the bioactive components mechanisms of prevention by integrated network pharmacology approach. Methods The putative ingredients its related targets were discerned from TCMSP Swiss target prediction database. After that, interacting with collected using...
Endometrial cancer (EC) is one of the most common gynecological cancers. Ferroptosis a newly identified form cell death characterized by iron-dependent lipid peroxide accumulation. Circular RNAs (circRNAs) have emerged as critical regulators for development. However, circRNA-mediated modulation ferroptosis in EC yet to be clarified. In this study, we found that circRAPGEF5 expression was elevated tissues compared normal endometrial tissues. vitro and vivo functional analysis demonstrated...
Tibia fracture in rats evokes chronic hindpaw warmth, edema, allodynia, and regional osteopenia resembling the clinical characteristics of patients with complex pain syndrome type I (CRPS I). Nerve growth factor (NGF) has been shown to support nociceptive other types changes found neuropathic models. We hypothesized that anti-NGF antibodies might reduce one or more CRPS I-like features rat model. For our studies distal tibia each experimental was fractured casted for 4 weeks. The were...
Objective To estimate the association between uterine fibroids and adverse obstetric outcomes. Methods This was a retrospective cross-sectional study of 112,403 deliveries from 14 provinces 39 different hospitals in 2011 mainland China. We compared pregnancy outcomes women with without who underwent detailed second trimester ultrasonography during 18 to 22 weeks. Obstetric include cesarean delivery, breech presentation, preterm placenta previa, placental abruption, premature rupture...
<h3>Background and Objectives</h3> Postdural puncture headache (PDPH) is a severe debilitating complication of unintentional dural puncture. The criterion-standard treatment for PDPH has been epidural blood patch (EBP), but it an invasive intervention with the potential complications, such as meningitis paralysis. We believe this first ever 17-year retrospective chart review in which we compare effectiveness sphenopalatine ganglion block (SPGB) to EBP postpartum patients. <h3>Methods</h3>...
Migraine constitute a disorder characterized by recurrent headaches, and have high prevalence, socio-economic burden severe effects on quality of life. Our previous fMRI study demonstrated that some brain regions are functional alterations in migraineurs. As the function human is related to its structure, we further investigated white gray matter structural In current study, used surface-based morphometry, voxel-based morphometry diffusion tensor imaging analyses detect 32 migraineurs...
Increasing evidence has suggested that the cerebellum is associated with pain and migraine. In addition, descending system of brainstem major site trigeminal processing modulation been discussed as a main player in pathophysiology Cerebellar structural changes migraineurs remain to be further investigated. Voxel-based morphometry (VBM) (50 controls, 50 without aura (MWoAs)) diffusion tensor imaging (DTI) (46 46 MWoAs) were used assess anatomical alterations MWoAs. We utilized spatially...
No recent data exist on human papillomavirus (HPV) infection in Beijing, People's Republic of China. We interviewed and examined a representative, randomly selected sample 5552 sexually active women aged 25–54 years. Cervical cell samples were analysed for HPV DNA by MY09/11-based PCR assay. Human prevalence was 6.7% overall 4.8% among without cervical abnormalities. Of the 21 subtypes identified, HPV16 commonest type (2.6% overall; 39.1% HPV-positive women), followed 58 (1.0%), 33 (0.8%),...
Rheum palmatum L. (RPL) is a known traditional herbal medicine with the functions of "heat-clearing and damp-drying" in Chinese medicine. Its anti-cancer effect against lung cancer has been confirmed previously, but related mechanisms active substances for its action little studied. This study adopted network pharmacology, built map drug ingredients disease targets (DDN), discussed effective components RPL possible mechanisms. All constituents were collected through database search...
Circulating microRNAs (miRNAs) have recently emerged as promising biomarkers for acute ischaemic stroke (AIS). However, the expression profiles of miRNAs in AIS patients receiving intravenous thrombolysis, and their associations with outcome not been investigated.In a prospective cohort study, total 84 patients, who received thrombolysis (21.4% combined reperfusion therapy) completed 3 month follow-up visits, were included. Favourable unfavourable outcomes defined modified Rankin Scale (mRS)...
Abstract Background Migraine is a severe and disabling brain disorder, the exact neurological mechanisms remain unclear. Migraineurs have altered pain perception, headache attacks disrupt their sensory information processing sensorimotor integration. The functional connectivity of sub-regions areas with other cortex associated migraine needs further investigation. Methods Forty-eight migraineurs without aura during interictal phase 48 age- sex-matched healthy controls underwent resting-state...
The in-situ studies of the corrosion product film on nickel-aluminum bronze are significant for explaining mechanism its resistance. In this paper, behavior and formation process protective in 3.5 wt % NaCl solution systematically investigated. results scanning electron microscope analysis electrochemical tests indicate that resistance is improved due to film. change local property during immersion time evaluated via vibrating electrode technique, it reveals evolution rules ionic flux real...
Abstract Adult attention deficit/hyperactivity disorder (ADHD), schizophrenia (SCHZ), and bipolar (BP) have common symptoms differences, the underlying neural mechanisms are still unclear. This article will thoroughly discuss differences between ADHD, BP, SCHZ (31 healthy control 31 ADHD; 34 BP; 42 SCHZ) relative to subjects in combination with three atlases (et al., Brainnetome atlas, Dosenbach Power atlas) seven entropies approximate entropy (ApEn), sample (SaEn), permutation (PeEn), fuzzy...
Long-term headache attacks may cause human brain network reorganization in patients with migraine. In the current study, we calculated topologic properties of functional networks based on Brainnetome atlas using graph theory analysis 29 female migraineurs without aura (MWoA) and age-matched healthy controls. Compared controls, MWoA exhibited that altered, nodal centralities decreased/increased some areas. particular, right posterior insula left medial superior occipital gyrus significantly...
Multiple microRNAs (miRNAs) participate in the response to hypoxic/ischemic and ischemia-reperfusion events. However, expression of these miRNAs circulation from patients with acute ischemic stroke (AIS) receiving recanalization treatment has not been examined, whether they are associated severity outcome is still unknown.In this prospective cohort study, plasma levels miR-125b-5p, miR-15a-3p, miR-15a-5p, miR-206 were measured at 24 hours after thrombolysis or without endovascular 94 AIS, as...