A5060573440- Vibrio bacteria research studies
- Viral gastroenteritis research and epidemiology
- Salmonella and Campylobacter epidemiology
- Vaccine Coverage and Hesitancy
- Ethics in Clinical Research
- Escherichia coli research studies
- Anomaly Detection Techniques and Applications
- Child Nutrition and Water Access
- Retinal Imaging and Analysis
- Cryptography and Data Security
- Artificial Intelligence in Healthcare
- Biomedical Ethics and Regulation
- Internet Traffic Analysis and Secure E-voting
- Advanced Neural Network Applications
- Amoebic Infections and Treatments
- SARS-CoV-2 and COVID-19 Research
- Viral Infections and Outbreaks Research
- Clostridium difficile and Clostridium perfringens research
- Advanced Image and Video Retrieval Techniques
- Advanced Steganography and Watermarking Techniques
- COVID-19 diagnosis using AI
- Influenza Virus Research Studies
- Health Systems, Economic Evaluations, Quality of Life
International Vaccine Institute
2021-2024
P.V. Narsimha Rao Telangana Veterinary University
2023
Osmania University
2023
Oklahoma State University
2015
In October, 2017, WHO launched a strategy to eliminate cholera by 2030. A primary challenge in meeting this goal is the limited global supply capacity of oral vaccine and worsening outbreaks since 2021. To help address current shortage vaccine, prequalified Euvichol-Plus was reformulated reducing number components inactivation methods. We aimed evaluate immunogenicity safety Euvichol-S (EuBiologics, Seoul, South Korea) compared with an active control Shanchol (Sanofi Healthcare India,...
Typhoid fever is an endemic disease in many low-income and middle-income countries. The 2018 WHO position paper recommends that countries should consider typhoid vaccination high-risk groups for outbreak control. To address the vaccine supply demand gap, a Vi polysaccharide-diphtheria toxoid (Vi-DT) conjugate development effort was undertaken to achieve prequalification contribute global of vaccine. main aim this study show immune non-inferiority Vi-DT compared with prequalified...
With the rapid growth of social media, number images being uploaded to internet is exploding. Massive quantities are shared through multi-platform services such as Snap chat, Instagram, Facebook and Whats App, recent studies estimate that over 1.8 billion photos every day. However, for most part, applications make use this vast data have yet emerge. Most current image processing applications, designed small-scale, local computation, do not scale well web-sized problems with their large...
Typhoid remains one of the major serious health concerns for children in developing countries. With extremely drug-resistant cases emerging, preventative measures like sanitation and vaccination, including typhoid conjugate vaccines (TCV) remain mainstay its prevention control. Different types TCVs are being developed to meet global demand. This report outlines results from a study done assess immunogenicity safety Vi-Diphtheria toxoid (Vi-DT) TCV Nepal. The was randomized,...
Clinical trials are complicated, time-consuming and costly. From the initial screening, informed consent recruitment of participants' to study completion, sponsor must undertake a wide array complex closely monitored operations, complying with international standards for human subject research local requirements. Conducting these studies in an underdeveloped country, limited resources, infrastructure, experience regulated clinical adds this complexity. The site selection, set up preparatory...
This open-label study assessed the safety and immunogenicity of two doses (14 days apart) an indigenously manufactured, killed, bivalent (Vibrio cholerae O1 O139), whole-cell oral cholera vaccine (SHANCHOL; Shantha Biotechnics) in healthy adults (n = 100) children a endemic area (Vellore, South India) to fulfill post-licensure regulatory requirements post-World Health Organization (WHO) prequalification commitments. Safety reactogenicity were assessed, seroconversion rates (i.e. proportion...
Background: To help address the current shortage of vaccine, a WHO prequalified bivalent whole cell (WC) OCV, Euvichol-Plus was reformulated by reducing number components and inactivation methods. Methods: The phase 3, observer-blind, randomized, active-controlled trial performed in healthy participants aged 1-40 years Nepal.Eligible were enrolled to receive two doses either Euvichol-S (Euvichol-Simplified, process-optimized monovalent WC OCV containing components) or an active control...
Clinical trials (CT) have been the cornerstones in developing medicines, vaccines, and new interventions. Despite tremendous efforts, a CT cannot succeed without participants' involvement. Various factors can affect people's attitude participation CT. Hence, this study was conducted to assess knowledge perception of clinical trial among participants at B.P. Koirala Institute Health Sciences, Dharan, Nepal. This population-based descriptive cross-sectional during 2021–2022. Participants...
Clinical trials are the most rigorous scientific and regulated method to investigate safety efficacy of vaccines or drugs in pre-licensure stage. trial design implementation complex, time-consuming involves close engagement with country's regulatory authority, clinical sites, investigators, healthcare system. Over past few decades, a significant number have been conducted low- middle-income countries (LMICs), particularly resource-limited settings. Conducting research LMICs leads capacity...