Jianning Chen

ORCID: 0000-0002-0905-4561
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About
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Research Areas
  • Radiomics and Machine Learning in Medical Imaging
  • Glioma Diagnosis and Treatment
  • MRI in cancer diagnosis
  • Renin-Angiotensin System Studies
  • Breast Cancer Treatment Studies
  • Liver Disease and Transplantation
  • Vascular Malformations Diagnosis and Treatment
  • Sport and Mega-Event Impacts
  • Medical Imaging and Analysis
  • Glutathione Transferases and Polymorphisms
  • Brain Metastases and Treatment
  • Visual perception and processing mechanisms
  • Environmental and Agricultural Sciences
  • Liver Disease Diagnosis and Treatment
  • AI in cancer detection
  • Takotsubo Cardiomyopathy and Associated Phenomena
  • GABA and Rice Research
  • Treatment of Major Depression
  • Cardiac Health and Mental Health
  • Galectins and Cancer Biology
  • Electroconvulsive Therapy Studies
  • Genetics, Aging, and Longevity in Model Organisms
  • Biological and pharmacological studies of plants
  • Education and Work Dynamics
  • Fetal and Pediatric Neurological Disorders

Third Affiliated Hospital of Sun Yat-sen University
2017-2025

Sun Yat-sen University
2017-2025

Zhejiang University
2022-2023

Hangzhou Seventh Peoples Hospital
2023

Southwest Medical University
2022

Feinstein Institute for Medical Research
2022

Quanzhou Normal University
2004-2011

Microvascular invasion (MVI) is a valuable predictor of survival in hepatocellular carcinoma (HCC) patients. This study developed predictive models using eXtreme Gradient Boosting (XGBoost) and deep learning based on CT images to predict MVI preoperatively. In total, 405 patients were included. A total 7302 radiomic features 17 radiological extracted by radiomics feature extraction package radiologists, respectively. We XGBoost model features, clinical variables three-dimensional...

10.1007/s00432-020-03366-9 article EN cc-by Journal of Cancer Research and Clinical Oncology 2020-08-27

The traditional Chinese medicine Gastrodia elata (commonly called "Tianma" in Chinese) has been widely used the treatment of rheumatism, epilepsy, paralysis, headache, and dizziness. Phenolic compounds, such as gastrodin, para-hydroxybenzyl alcohol (HBA), p-hydroxybenzaldehyde, vanillin are main bioactive components isolated from elata. These compounds not only structurally related but also share similar pharmacological activities, antioxidative anti-inflammatory effects on aging-related...

10.1155/2022/8986287 article EN cc-by Oxidative Medicine and Cellular Longevity 2022-03-31

Accurate measurement of the vibrotactile acuities human torso is key to designing effective torso-worn displays for healthcare applications such as navigation aids visually impaired persons. Although efforts have been made measure acuities, there remains a lack systematic studies addressing spatial, temporal, and intensity-related aspects sensitivity on torso. In this work, belt consisting two crossed coin motor arrays was designed psychophysical study carried out set subjects wearing belt....

10.3390/mi15111341 article EN cc-by Micromachines 2024-10-31

Stereotactic biopsies for lesions in the brainstem and deep brain are rare. This study aimed to summarize our 6-year experience accurate diagnosis of stem discuss technical note strategies. From December 2011 January 2018, 72 cases intracranial or lobes undergoing stereotactic biopsy were retrospectively reviewed. An individualized puncture path was designed based on lesion's location image characteristics. The most common targets (43 cases, 59.7%), including frontal lobe (33 45.8%),...

10.1590/1414-431x2021e11335 article EN cc-by Brazilian Journal of Medical and Biological Research 2021-01-01

Hepatitis B virus (HBV) infection is a major public health issue worldwide as it may cause serious liver diseases such cirrhosis and hepatocellular carcinoma (HCC). Ruling out important when treating chronic hepatitis (CHB). The aim of this study was to compare the performance aspartate aminotransferase-to-platelet ratio index (APRI), fibrosis score based on four factors (FIB-4), red cell volume distribution width-to-platelet (RPR) in diagnosing stages identify new cut-off values rule...

10.1016/j.livres.2023.08.006 article EN cc-by-nc-nd Liver Research 2023-09-01

Miliary dissemination is common in tuberculosis, but an extremely rare form of brain metastasis. It mainly found patients with primary lung cancer (small cell and adenocarcinoma). Here, we presented a case miliary metastases adenocarcinoma to the without lesion enhancement on MRI after administration contrast. A 38-year-old Chinese male was diagnosed received chemotherapy monthly for 6 months. At one month completion chemotherapy, patient headache, dizziness, vomiting. Brain revealed...

10.21037/tcr-20-1898 article EN Translational Cancer Research 2021-02-01

ABSTRACT Pituitary microadenoma (PM) is often difficult to detect by MR imaging alone. We employed a computer-aided PM diagnosis (PM-CAD) system based on deep learning assist radiologists in clinical workflow. enrolled 1,228 participants and stratified into 3 non-overlapping cohorts for training, validation testing purposes. Our PM-CAD outperformed 6 existing established convolutional neural network models detection of PM. In test dataset, diagnostic accuracy was comparable with > 10...

10.1101/2021.03.02.21252010 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2021-03-05

Objective To explore the clinicopathologic features of phyllodes tumors (PT) breast and indentify predictive factors local recurrence (LR). Methods Data sixty women with PT were collected analyzed from Third Affiliated Hospital Sun Yat-sen University. Results Compared borderline malignant tumors, patients suffered benign disease had longer clinical course, younger age, smaller tumor size poorer blood supply. Tumors demonstrating pushing borders, mild cellular pleomorphism,...

10.3877/cma.j.issn.1674-0793.2014.03.011 article EN Chin Arch Gen Surg(Electronic Edition) 2014-06-01

Objective To investigate the expressions of progesterone receptor a and b in breast invasive ductal carcinoma(IDC) their associations with clinical pathological factors prognosis. Methods The PR-a PR-b 100 specimens IDC were detected by immunohistochemistry. The correlations between PR-a, characteristics such as ER-α, ER-β, HER-2, Ki-67, axillary lymph node(ALN)metastases, cytological classification, TNM staging lymphovascular invasion analyzed, relationships PR-a/PR-b ratio these...

10.3877/cma.j.issn.1674-0793.2013.04.005 article EN Chin Arch Gen Surg(Electronic Edition) 2013-08-01

Objective To investigate the relationship between apparent diffusion coefficient (ADC) values and histopathological grading of cerebral gliomas. Methods A retrospective analysis was performed to clinical data 76 patients with gliomas, admitted our hospital from April 2013 December 2016. According Classification Criteria Central Nervous System Tumors by WHO in 2016, these were divided into low grade glioma group (grading I-II, n=21), moderate III, n=23) high IV, n=32). MR imaging,...

10.3760/cma.j.issn.1671-8925.2017.10.013 article EN Chinese Journal of Neuromedicine 2017-10-15

Objective To evaluate the relationship between diffusion weighted imaging visual signal intensity and quantitative of cell renal carcinoma (CCRCC) histopathological differentiation CCRCC. Methods This retrospective analysis included 91 patients with CCRCC confirmed by pathology. All were grouped according to Fuhrman pathological grading system, from Ⅰto Ⅵ. Four grades merged into three classifications consisting 37 well-differentiated CCRCCs (Ⅰ Ⅱ), 32 moderately-differentiated (Ⅲ) 22...

10.3877/cma.j.issn.1674-3253.2018.01.013 article EN Chin J Endourol(Electronic Edition) 2018-02-01
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