- Medical Imaging Techniques and Applications
- Cell death mechanisms and regulation
- Advanced X-ray and CT Imaging
- Cerebrospinal fluid and hydrocephalus
- Lung Cancer Research Studies
- Neuroendocrine Tumor Research Advances
- Neuroblastoma Research and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Amyotrophic Lateral Sclerosis Research
- Neurological disorders and treatments
- Cancer Research and Treatment
- Polymer Surface Interaction Studies
- Radiation Therapy and Dosimetry
- Electrospun Nanofibers in Biomedical Applications
- Prostate Cancer Treatment and Research
- Radiation Detection and Scintillator Technologies
- Metabolism, Diabetes, and Cancer
- Acute Myeloid Leukemia Research
- Lymphoma Diagnosis and Treatment
- Cell Image Analysis Techniques
- Brain Tumor Detection and Classification
- biodegradable polymer synthesis and properties
- Diet and metabolism studies
- Advanced Radiotherapy Techniques
- RNA Interference and Gene Delivery
Universitair Ziekenhuis Leuven
2020-2024
KU Leuven
2020-2024
Ghent University
2007-2009
VIB-UGent Center for Medical Biotechnology
2007
Abstract Polyelectrolyte microcapsules are made by layer‐by‐layer (LbL) coating of a sacrificial template, followed decomposition the to produce hollow microcapsules. In this paper, we report on in vivo cellular uptake, degradation and biocompatibility polyelectrolyte produced from alternating dextran sulphate poly‐L‐arginine layers template calcium carbonate microparticles. We show that moderate tissue reaction is observed after subcutaneous injection mice. Within sixteen days injection,...
Fluorine-18-labeled SSAs have the potential to become next-generation tracer in SSTR-imaging neuroendocrine tumor (NET) patients given their logistical advantages over current gold standard gallium-68-labeled SSAs. In particular, [18F]AlF-OC has already shown excellent clinical performance. We demonstrated our previous report from prospective multicenter trial that PET/CT outperforms [68Ga]Ga-DOTA-SSA, but histological confirmation was lacking due ethical and practical reasons. this second...
Baseline metabolic tumor volume (MTV) is a promising prognostic marker in diffuse large B-cell lymphoma (DLBCL). We assessed the value of 4 novel risk scores real-life DLBCL cohort and compared them with revised international index (IPI).
Somatostatin receptor (SSTR) positron emission tomography (PET) is a cornerstone of neuroendocrine tumor (NET) management. Hybrid PET/magnetic resonance imaging (MRI) now available for NET-imaging, next to PET/computed (CT).To determine whether CT or MRI the best hybrid partner [68Ga]Ga-DOTATATE PET.Monocentric, prospective study.Patients received same-day PET/CT and subsequent PET/MRI, suspicion NET, (re)staging peptide radionuclide therapy-selection. The union (PETunion) malignant lesions...
Abstract Purpose The aim of this study was to develop a CNN model for automatic detection and segmentation primary brain tumors using 18 F-fluoroethyl-L-tyrosine ( F-FET) PET. Methods Eighty-four patients who underwent 40 min dynamic F-FET PET were retrospectively included. Ground truth labels the lesions background regions defined by nuclear medicine physician MIM software. A multi-label developed segment lesion region 20–40 static scan. In addition, single-label implemented lesion-only...