- Essential Oils and Antimicrobial Activity
- Nanoparticles: synthesis and applications
- Bacterial biofilms and quorum sensing
- Tuberculosis Research and Epidemiology
- Graphene and Nanomaterials Applications
- Synthesis and biological activity
- Mycobacterium research and diagnosis
- Metabolomics and Mass Spectrometry Studies
- Pharmacological Effects of Natural Compounds
- Ethnobotanical and Medicinal Plants Studies
- Synthesis and Biological Evaluation
- Nanoparticle-Based Drug Delivery
- Cancer therapeutics and mechanisms
- thermodynamics and calorimetric analyses
- Plant chemical constituents analysis
- Computational Drug Discovery Methods
- Antifungal resistance and susceptibility
- Piperaceae Chemical and Biological Studies
- Microbial Natural Products and Biosynthesis
- Biosensors and Analytical Detection
- Inhalation and Respiratory Drug Delivery
- HIV/AIDS Impact and Responses
- Morinda citrifolia extract uses
- Advanced Drug Delivery Systems
- 3D Printing in Biomedical Research
Corporación para Investigaciones Biológicas
2017
Aga Khan University Hospital
2015
Instituto Nacional de Salud
2009-2014
Universidad del Valle
2014
Sungkyunkwan University
2011
Universidad de Antioquia
2003-2010
Journal Article In vitro activity of fluconazole, itraconazole, voriconazole and terbinafine against fungi causing onychomycosis Get access J. G. Bueno, Bueno Department Microbiology Parasitology, Infection Cancer Group, University Antioquia, Medellin, Colombia Search for other works by this author on: Oxford Academic Google Scholar C. Martinez, Martinez B. Zapata, Zapata Sanclemente, Sanclemente Group Investigative Dermatology – GRID, Section, School Medicine, M. Gallego, Gallego Medical...
The emergence of multidrug-resistant strains Mycobacterium tuberculosis underscores the need continuous developments on new and efficient methods to determine susceptibility isolates M. in search for novel antimicrobial agents. Natural products constitute an important source drugs, but design implementation antimycobacterial testing are necessary evaluate different extracts compounds. A number biological assay methodologies current use, ranging from classical disk diffusion broth dilution...
This declaration, signed by an interdisciplinary task force of 234 experts from 83 different countries with backgrounds, highlights the threat posed antimicrobial resistance and need for appropriate use antibiotic agents antifungal in hospitals worldwide especially focusing on surgical infections.As such, it is our intent to raise awareness among healthcare workers improve prescribing.To facilitate its dissemination, declaration was translated languages.A ntimicrobial (AMR) has emerged as...
Introduction. Human tuberculosis is a contagious-infectious disease mainly caused by Mycobacterium tuberculosis. Although regimens exist for treating tuberculosis, they are far from ideal. Development of effective strategies treatment human has posed challenge, considering the increase in infections associated with immunodeficiency virus and immunocompromised patients. Essential oils -volatile, aromatic oil extracts plants-have been used traditional many diseases; however careful...
Tuberculosis (TB) is the most ancient epidemic disease in world and a serious opportunistic HIV/AIDS patients. The increase multidrug resistant Mycobacterium tuberculosis (MDR-TB, XDR-TB) demands search for novel antimycobacterial drugs. Essential oils (EOs) have been widely used medicine some EOs their major components shown to be active against M. tuberculosis. aim of this work was evaluate cell toxicity activities three derived from Salvia aratocensis, Turnera diffusa Lippia americana,...
Currently, the emergence of multidrug resistant microorganisms as Acinetobacter baumannii and Mycobacterium tuberculosis well new drug forms Neisseria gonorrhoeae in conjunction with evolving resistance genes KPC (class A Klebsiella pneumoniae) NDM-1 (New Delhi metallo-β-lactamase 1) carbapenemases are a public health threat that requires great efforts prevention, treatment diagnosis. For reason, InterAcademy Panel Medical statement (IAP-IAMP) included their Global recommendations call for...
Biofilm is a reservoir of drug resistant microorganisms that can increase the failure rate anti-infective therapy and public health concern.Antibiofilm discovery necessary for developing new drugs, biocides wound management protocols.This makes standardization implementation in vitro antibiofilm screening platforms challenge search antibiotics, because current antimicrobials are active against planktonic bacteria have poor diffusion across biofilm matrix.Usually, based research topic,...
In previous comments, the difficulties and technical problems of selectivity criteria was exposed related to the antimicrobial activity extracts plants pure compounds based in MICs, opening an interesting discussion about this topic. this way, commentary seeks give more elements that feed proposed debate.
Antimicrobial drug resistance is a current public health problem, which compounded by the misuse of antibiotics in medical practice and emergence Multidrug-Resistant (MDR) microorganisms.Therefore it necessary to develop new anti-infective drugs implement methodologies able establish Susceptibility (AST) field point-of-care.In this sense biosensors promising technology that can detect MDR strains small molecules various samples, these devices have advantages be miniaturized for obtain...
In the present study, nineteen new fluoro-benzimidazole derivatives, including nifuroxazide analogs, were synthesized by microwave-supported reactions and tested against a panel of pathogenic microorganisms consisting resistant strains. The compounds characterized identified FT-IR, 1H- 13C-NMR, mass spectroscopy, elemental analyses, respectively. vitro antimicrobial cytotoxic effects determined microdilution [3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide] (MTT) assay....
Abstract The essential oils from Lippia alba (Miller) N.E Brown (Verbenaceae Family) collected in different regions of Colombia were obtained by microwave-assisted hydrodistillation. Their chemical compositions determined GC and GC/MS. Two chemotypes distinguished, characterized carvone citral as main constituents. Antifungal activity the was following standard microdilution protocols AFST-EUCAST for C. krusei parasilopsis, CLSI-M38A Aspergillus fumigatus A. flavus. both L. showed antifungal...
The antimycobacterial activity of new 18 7-chloroquinoline derivatives, obtained from 4,7-dichloroquinoline, was evaluated against 15 Mycobacterium spp among standardized and clinical isolates using the MTT susceptibility test to obtain minimum inhibitory concentration values (MIC, μg/mL). results suggested that compounds are useful leads for anti-TB drug development. most active exhibited moderate with 16 μg/mL MIC all tested microorganisms. Keywords: 7-Chloroquinoline Synthesis, MDR-TB,...
Plants of the Piperaceae family have been used with medicinal purposes in different regions around world. In vitro antifungal activity 10 essential oils from species Piper genus were measured by determination minimum inhibitory concentration (MIC) against A. flavus fungi ATCC 204304 and fumigatus 204305 following standard protocol CLSI M38-A. addition, Candida krusei 6258 C. parapsilosis 22019 evaluated modified M27-A2. The oil most was sanctifelisis for (CMI: 125 µg/mL).