Akira Handa

ORCID: 0000-0002-0917-7035
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Cerebrovascular and Carotid Artery Diseases
  • Intracranial Aneurysms: Treatment and Complications
  • Acute Ischemic Stroke Management
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Vascular Malformations Diagnosis and Treatment
  • Cardiovascular Health and Disease Prevention
  • Venous Thromboembolism Diagnosis and Management
  • Cardiovascular Disease and Adiposity
  • Moyamoya disease diagnosis and treatment
  • Cerebral Venous Sinus Thrombosis
  • Peripheral Artery Disease Management
  • Neurosurgical Procedures and Complications
  • Aortic Disease and Treatment Approaches
  • Cerebrospinal fluid and hydrocephalus
  • Diagnosis and Treatment of Venous Diseases
  • Aortic aneurysm repair treatments
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Coronary Interventions and Diagnostics
  • Vascular Procedures and Complications
  • Neurological Complications and Syndromes
  • Spine and Intervertebral Disc Pathology
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Biliary and Gastrointestinal Fistulas
  • Histiocytic Disorders and Treatments
  • Cardiovascular and Diving-Related Complications

Hokuto Hospital
2025

Kurashiki Central Hospital
2013-2022

Handa City Hospital
2013-2019

Akira (France)
2013-2019

Yamagata University
2018

Nuffield Orthopaedic Centre
2015

Montreal Neurological Institute and Hospital
2015

McGill University Health Centre
2015

Shizuoka General Hospital
2013

Okayama University
1994-2010

Background Endovascular therapy has been shown to be effective in patients with acute cerebral large‐vessel occlusion, but real‐world efficacies are unknown. Methods and Results We conducted a prospective registry at 46 centers between October 2014 January 2017. Eligible were those who aged 20 years or older, hospitalized within 24 hours of the onset. enrolled both consecutive treated without endovascular therapy. included thrombectomy, balloon angioplasty, stenting, local fibrinolysis,...

10.1161/jaha.118.008796 article EN cc-by-nc-nd Journal of the American Heart Association 2018-04-25

Endovascular therapy (EVT) is strongly recommended for acute cerebral large vessel occlusion with the Alberta Stroke Program Early CT Score (ASPECTS) ≥6 due to of internal carotid artery or M1 segment middle artery. However, effect EVT patients who have ischemic core ASPECTS ≤5 (0–5) was not established. The purpose this study elucidate outcomes core.Based on data Recovery by Salvage Cerebral Ultra-Acute Embolism Japan Registry 2, and pretreatment 0 5 noncontrast diffusion-weighted image...

10.1161/strokeaha.118.024646 article EN Stroke 2019-03-18

To develop a vessel model with poly-vinyl alcohol hydrogel (PVA-H) low surface friction for in vitro simulations of vascular pathologies.Simulations variable pathologies were based on human casts reproduced wax. Constructions models then obtained by lost wax techniques. As materials, liquid silicon or PVA organic solvents used. After solidification, the was drained heating. Comparison PVA-H silicone included evaluation characteristics (friction coefficient), visibility (transparence and...

10.3233/thc-2004-12302 article EN Technology and Health Care 2004-08-18

OBJECTIVE Plasma D-dimer levels elevate during acute stages of aneurysmal subarachnoid hemorrhage (SAH) and are associated with poor functional outcomes. However, the mechanism in which elevation on admission affects outcomes remains unknown. The aim this study is to clarify whether correlated systemic complications after SAH, investigate their additive predictive value conventional risk factors for METHODS A total 187 patients SAH were retrospectively analyzed from a single-center,...

10.3171/2016.5.jns16767 article EN Journal of neurosurgery 2016-08-12

Plaque characteristics and morphology are important indicators of plaque vulnerability. MRI-detected intraplaque hemorrhage has a great effect on Expansive remodeling, which been considered compensatory enlargement the arterial wall in progression atherosclerosis, is one criteria vulnerable coronary circulation. The purpose this study was risk stratification carotid artery through evaluation quantitative expansive remodeling MRI signal intensity.Both preoperative T1-weighted axial long-axis...

10.3171/2015.2.jns142783 article EN Journal of neurosurgery 2015-09-11

OBJECTIVE Delayed cerebral ischemia (DCI) is an important complication after aneurysmal subarachnoid hemorrhage (aSAH). Although intrathecal milrinone injection via lumbar catheter to prevent DCI has been previously reported be safe and feasible, its effectiveness remains unknown. The goal of this study was evaluate whether treatment aSAH significantly reduced the incidence DCI. METHODS prospectively maintained database used identify patients treated between January 2010 December 2015....

10.3171/2016.10.jns162227 article EN Journal of neurosurgery 2017-03-03

Acute pancreatitis (AP) is a leading cause of gastrointestinal hospitalizations, with gallstones and alcohol being the most common etiologies. Although viral infections have been implicated in pancreatitis, association between COVID-19 pancreatic inflammation remains under investigation. We present case 67-year-old male no prior history who developed severe AP multi-organ failure following SARS-CoV-2 infection. The patient experienced acute epigastric pain, nausea, vomiting, laboratory...

10.36347/sjmcr.2025.v13i03.014 article EN Scholars Journal of Medical Case Reports 2025-03-11

To evaluate the risk factors, location, treatment, and outcomes of stroke due to arterial dissection, we examined these characteristics in a substantial, long-standing, nationwide cohort. The study participants were patients with acute who registered Japan Stroke Data Bank between January 1999 December 2020. We focused on caused by extracranial or intracranial artery dissection their clinical characteristics, treatments, outcomes. In addition, compared results subtypes without dissection....

10.5551/jat.65517 article EN Journal of Atherosclerosis and Thrombosis 2025-01-01

Acute Esophageal Necrosis (AEN), or "black esophagus," is a rare but severe condition primarily affecting elderly patients with multiple comorbidities. It characterized by diffuse circumferential black discoloration of the esophageal mucosa, usually resulting from ischemia, impaired mucosal defenses, and exposure to gastric contents. We present case 75-year-old female patient congestive heart failure atherosclerosis who was diagnosed AEN during an esophagogastroduodenoscopy performed for...

10.36347/sjmcr.2025.v13i04.036 article EN Scholars Journal of Medical Case Reports 2025-04-26

Oral contraceptives are widely used for birth control, but their potential hepatic side effects remain a concern. This article presents rare case of 45-year-old woman, mother four, who developed both Budd-Chiari syndrome and peliosis hepatis, with no other identifiable risk factors, after long-term oral contraceptive use. The highlights the importance careful monitoring patients on prolonged hormonal contraception need increased awareness its hepatotoxic effects.

10.36347/sjmcr.2025.v13i04.035 article EN Scholars Journal of Medical Case Reports 2025-04-26

Background: Eosinophilic colitis (EC) is a rare form of primary eosinophilic gastrointestinal disorder, predominantly affecting neonates and young adults. Unlike esophagitis, EC remains poorly understood, with limited data derived from small case series reports. It characterized by infiltration the intestinal wall, submucosal edema, peripheral eosinophilia. However, presence eosinophils in colonic biopsies necessitates ruling out secondary causes, making diagnosis exclusion. Case...

10.36347/sjmcr.2025.v13i05.058 article EN Scholars Journal of Medical Case Reports 2025-05-17

Thyroid hormones, including thyroxine (T4) and triiodothyronine (T3), play a crucial role in regulating the basal metabolic rate of all cells, hepatocytes, thereby influencing liver function. While hepatic dysfunction is frequently observed hyperthyroidism, it often mild asymptomatic. However, cholestatic jaundice as primary manifestation hyperthyroidism exceedingly rare. We report case 33-year-old patient presenting with pruritus. Laboratory tests revealed elevated alanine aminotransferase...

10.36347/sjmcr.2025.v13i05.057 article EN Scholars Journal of Medical Case Reports 2025-05-16

Perianal fistula is a common clinical condition, typically resulting from abscess formation of the anal glands or as complication surgical intervention. Malignant transformation chronic fistulas in ano rare, accounting for 3% to 11% all canal malignancies. Mucinous adenocarcinoma, subtype especially rare within perianal tracts. Here, we report case 42-year-old male with pain and discharging 3 years' duration, who underwent surgery but experienced recurrence. Adenocarcinoma was diagnosed...

10.36347/sjmcr.2025.v13i05.059 article EN Scholars Journal of Medical Case Reports 2025-05-17

✓ Twelve patients with Hunt and Hess neurological Grades III to V underwent thrombosis of aneurysms using cellulose acetate polymer within 23 hours aneurysm rupture. On computerized tomography (CT), nine these had diffuse or localized thick subarachnoid blood clots, two thin one intraventricular clots. Immediately after thrombosis, all were administered tissue plasminogen activator (TPA) through spinal ventricular catheters. The pressure the lumbar cerebrospinal fluid was maintained at 100...

10.3171/jns.1995.83.1.0034 article EN Journal of neurosurgery 1995-07-01

Intraplaque hemorrhage, detected as a high-signal intensity on carotid MRI, is also strongly associated with ischemic events in symptomatic patients. However, asymptomatic patients, the relationship of T1-high intense plaque and subsequent stroke not clear. The aim this study to test hypothesis that risk factor for cerebrovascular event.Of 1,353 consecutive who underwent head MRI part their annual medical check-up, imaging quality 13 was poor 150 did present follow-up examination, thus...

10.1159/000455973 article EN Cerebrovascular Diseases 2017-01-01

Background and Purpose— The treatment prognosis of acute large vessel occlusion with mild symptoms have not been sufficiently studied. present study aimed to investigate the clinical or radiological predictors outcome in patients stroke due occlusion. Methods— Of 2420 RESCUE-Japan Registry 2 (Recovery by Endovascular Salvage for Cerebral Ultra-Acute Embolism-Japan 2), a multicenter prospective registry Japan, modified Rankin Scale scores 0 before onset initial National Institutes Health...

10.1161/strokeaha.119.028562 article EN Stroke 2020-04-16

Reduced cerebrovascular reserve (CVR) is associated with increased risk of ischemic events in carotid steno-occlusive diseases.To determine whether pretreatment CVR can predict postoperative lesions after artery stenting (CAS) by retrospective analysis.We retrospectively reviewed the medical records 46 patients (42 men; mean age 74.2±8.3 years) who underwent CAS and preprocedural cerebral blood flow measurement quantitative single-photon emission CT. Ischemic were evaluated...

10.1136/neurintsurg-2014-011163 article EN Journal of NeuroInterventional Surgery 2014-09-03

With the advancement of an aging society in world, increasing number elderly patients have been hospitalized due to aneurysmal subarachnoid hemorrhage (aSAH). There is no study that compares cases aSAH who receive definitive treatment with those treated conservatively. The aim this was investigate feasibility surgery for acute aged 80 or older.We reviewed 500 consecutive surgical indication aneurysm repair. Inoperable such as dead-on-arrival and both pupils dilated were excluded. We compared...

10.1136/neurintsurg-2013-010951 article EN Journal of NeuroInterventional Surgery 2013-10-23

Although endovascular therapy is favored for acutely ruptured intracranial aneurysms, hematological factors associated with acute subarachnoid hemorrhage (SAH) may predispose to procedure-related ischemic complications. The aim of this study was evaluate whether an elevated level plasma D-dimer, a parameter hypercoagulation in patients SAH, correlated increased incidence thromboembolic events during coiling aneurysms.

10.3171/2017.7.jns171129 article EN Journal of neurosurgery 2018-02-09
Coming Soon ...