A5061412464- Cancer survivorship and care
- Palliative Care and End-of-Life Issues
- Health Systems, Economic Evaluations, Quality of Life
- Childhood Cancer Survivors' Quality of Life
- Nutrition and Health in Aging
- Frailty in Older Adults
- Patient-Provider Communication in Healthcare
- Clinical practice guidelines implementation
- Cancer-related cognitive impairment studies
- Estrogen and related hormone effects
- Management of metastatic bone disease
- Economic and Financial Impacts of Cancer
- Global Cancer Incidence and Screening
- Head and Neck Cancer Studies
- Complementary and Alternative Medicine Studies
- Cerebral Palsy and Movement Disorders
- Patient Satisfaction in Healthcare
- Neutropenia and Cancer Infections
- Cancer Treatment and Pharmacology
- Protein purification and stability
- Analytic Number Theory Research
- Statistical Methods in Clinical Trials
- Occupational Therapy Practice and Research
- Medical Practices and Rehabilitation
- Digital Games and Media
Martin Luther University Halle-Wittenberg
2016-2025
University Hospital in Halle
2021-2025
Luther University
2014-2023
Sächsische Krebsgesellschaft
2020
Complejo Hospitalario de Navarra
2016
Sahlgrenska University Hospital
2016
Jagiellonian University
2016
University of Würzburg
1967-2013
Roche (Switzerland)
2011
Heidelberg University
2001
The European Organisation for Research and Treatment of Cancer (EORTC) Group has developed a new multidimensional instrument measuring cancer-related fatigue to be used in conjunction with the quality life core questionnaire (EORTC QLQ-C30). module EORTC QLQ-FA13 assesses physical, cognitive, emotional aspects fatigue.The methodology follows guidelines phase IV validation modules. This paper focuses on results psychometric factorial structure module. For cross-validation confirmatory factor...
Patients' self-management skills are affected by their knowledge, activities, and attitudes toward pain management. This trial aimed to test the Self Care Improvement through Oncology Nursing (SCION)-PAIN program, a multimodular structured intervention reduce patients' barriers of cancer pain. Two hundred sixty-three patients with diagnosed malignancy, pain>3 days, average > or = 3/10 participated in cluster-randomized on 18 wards 2 German university hospitals. Patients received, addition...
Patient-reported physical function (PF) is a key endpoint in cancer clinical trials. Using complex statistical methods, common metrics have been developed to compare scores from different patient-reported outcome (PRO) measures, but such methods do not account for possible differences questionnaire content. Therefore, the aim of our study was content comparison frequently used PRO measures PF patients.
Advances in cancer care delivery require revision and further development of questionnaires assessing patients' perceived quality care. This study pre-tested the revised EORTC satisfaction with core questionnaire applicable both inpatient outpatient settings, its new, outpatient-specific complementary module. The process revision, extended application, pre-testing these was based on phases I to III "EORTC Quality Life Group Module Development Guidelines." In phase III, patients 11 countries...
Die systematische Erfassung gesundheitsbezogener Selbsteinschätzungen von Patient*innen mittels Patient-Reported Outcome Measures (PROM) kann dazu beitragen, die Patientenperspektive stärker in den Versorgungsprozess zu integrieren und onkologische Supportiv- Palliativversorgung verbessern. Eine elektronische PROM ermöglicht nicht nur hohe Nutzerfreundlichkeit bei der Dateneingabe, sondern durch automatisierte Prozesse auch eine erleichterte Datenauswertung übersichtliche...
Cancer and its treatment can have substantial impact on patients' emotional functioning. Several patient-reported outcome measures (PROMs) assessing functioning are available, but differences in content limit the comparability of results. To better understand conceptual (dis)similarities, we conducted a comparison commonly used PROMs.We included items, scales, item banks from EORTC CAT Core, QLQ-C30, FACT-G, Hospital anxiety depression scale (HADS), SF-36, PRO-CTCAE, PROMIS (item for...
The European Organisation for Research and Treatment of Cancer Quality Life Group (EORTC QLG) has developed a multidimensional instrument measuring cancer-related fatigue, the EORTC QLQ-FA12. analysis sensitivity to change is an essential part psychometric validation. With this study, we investigated QLQ-FA12's change.The methodology follows guidelines QLG phase IV validation modules. We included cancer patients undergoing curative palliative treatment at t1 followed them up prospectively...
Abstract Purpose Despite evidence for clinical benefits, recommendations in guidelines, and options electronic data collection, routine assessment of patient-reported outcomes (PROs) is mostly not implemented practice. This study aimed to plan, conduct evaluate the implementation PRO (e-PRO) an inpatient radiation oncology clinic. Methods The guideline- evidence-based, stepwise approach this single-center comprised preparatory analyses current practice, selection instruments times,...
The purpose of this single-centre prospective non-randomised study was to evaluate the effectiveness an interdisciplinary care programme enhance self-management in patients with haematopoietic stem cell transplantation (HSCT). Patients undergoing HSCT, aged >14 years informed consent were recruited (n = 79). intervention group (IG) received standard plus SCION-HSCT counteract three problems after HSCT: muscle weakness, oral mucositis and malnutrition. Control care. Primary endpoint global...
Cancer treatment for elderly patients is often complicated by poor physical condition, impaired functioning and comorbidities. Patient reported health related quality of life (HRQOL) can contribute to decisions about goals supportive therapy. Knowledge factors influencing HRQOL therefore needed the development measures care pathways. An exploratory secondary data analysis on 518 assessments European Organisation Research Treatment (EORTC) core questionnaire (EORTC QLQ-C30) module QLQ-ELD14)...
In line with the World Health Organizations' health definition, patient-reported outcome (PRO) measures frequently cover aspects of social health. Our study aimed to evaluate role functioning (RF) and (SF) contents assessed by PRO commonly used in cancer patients.We analysed item content SF RF domains EORTC CAT Core, QLQ-C30, SF-36, FACT-G as well PROMIS bank covering Ability Participate Social Roles Activities. Following an established methodology we linked International Classification...
Background The strategy of implementation the QbD (Quality by design) approach in upstream processing therapeutic proteins consists identification critical process parameters (CPPs) that have a statistically significant influence on quality attributes (CQAs) specific process. By applying acceptance criteria to CQAs, proven acceptable ranges (PARs) for CPPs can be deduced from experimental data. multidimensional combination these form design space and thus assures product. according ICH...