A5058647576- Soil Geostatistics and Mapping
- Forest ecology and management
- Data Analysis with R
- Hydrology and Drought Analysis
- Intestinal and Peritoneal Adhesions
- Climate change impacts on agriculture
- Liver Disease and Transplantation
- Economic and Financial Impacts of Cancer
- Health Systems, Economic Evaluations, Quality of Life
- Bayesian Methods and Mixture Models
- Global Cancer Incidence and Screening
- Climate variability and models
- Bayesian Modeling and Causal Inference
- Organ Transplantation Techniques and Outcomes
- Underwater Vehicles and Communication Systems
- Intravenous Infusion Technology and Safety
- Clinical Laboratory Practices and Quality Control
- Forest Management and Policy
- Advanced Statistical Methods and Models
- Childhood Cancer Survivors' Quality of Life
- Fish Ecology and Management Studies
- Cancer survivorship and care
- Colorectal Cancer Surgical Treatments
- Hydrology and Sediment Transport Processes
- Gastric Cancer Management and Outcomes
Universität Innsbruck
2019-2024
Hella (Germany)
2024
Cost-utility analysis generally requires valid preference-based measures (PBMs) to assess the utility of patient health. While generic PBMs are widely used, disease-specific may capture additional aspects health relevant for certain populations. This study investigates construct and concurrent criterion validity cancer-specific European Organisation Research Treatment Cancer (EORTC) Quality Life Utility-Core 10 dimensions (QLU-C10D) in non-small-cell lung cancer patients. We retrospectively...
The Quality of Life (QoL) Utility measure, QLU-C10D, is derived the European Organisation for Research and Treatment Cancer (EORTC) QoL Questionnaire, QLQ-C30. Based on cancer-specific nature, QLU-C10D expected to be sensitive responsive in lung cancer patients.This retrospective analysis used data from four international multi-center trials (NCT00656136, NCT00949650, NCT01085136, NCT01523587). Clinical validity was assessed comparison a generic standard utility instrument, EuroQoL Group´s...
To obtain a probabilistic model for dependent variable based on some set of explanatory variables, distributional approach is often adopted where the parameters distribution are linked to regressors. In many classical models this only captures location but over last decade there has been increasing interest in regression approaches modeling all including location, scale and shape. Notably, so-called nonhomogeneous Gaussian (NGR) both mean variance response particularly popular weather...
Abstract Objectives The Quality of Life (QoL) Utility measure, QLU-C10D, is derived the European Organisation for Research and Treatment Cancer (EORTC) QoL Questionnaire, QLQ-C30. Based on cancer-specific nature, QLU-C10D expected to be sensitive responsive in lung cancer patients. Methods This retrospective analysis used data from four multi-center trials. Clinical validity was assessed comparison a generic standard utility instrument, EuroQoL Group´s EQ-5D-3L. Utilities six country tariffs...
Summary Although circular data occur in a wide range of scientific fields, the methodology for distributional modelling and probabilistic forecasting response variables is quite limited. Most existing methods are built on generalized linear additive models, which often challenging to optimize interpret. Specifically, capturing abrupt changes or interactions not straightforward but relevant, e.g. wind directions subject different regimes. Additionally, automatic covariate selection desirable...
Background. Hemodynamic instability after liver graft reperfusion increases recipient morbidity transplantation. The etiologies of hemodynamic disturbances appear to be multifactorial and are poorly understood. Normothermic machine perfusion (NMP) provides an opportunity analyze quality prior In the present study, we aim investigate influence interleukin-6 (IL-6) levels during NMP on postreperfusion hemodynamics recipient. Methods. Consecutive NMP-liver transplants at a single-center were...
Liver retransplantation (reLT) yields poorer outcomes than primary liver transplantation, necessitating careful patient selection to avoid futile reLT. We conducted a retrospective analysis assess reLT and identify associated risk factors. All adult patients who underwent first at the Medical University of Innsbruck from 2000 2021 (N = 111) were included. Graft- survival assessed via Kaplan-Meier plots log-rank tests. Uni- multivariate analyses performed independent predictors graft loss....
A core step of every algorithm for learning regression trees is the selection best splitting variable from available covariates and corresponding split point. Early tree algorithms (e.g., AID, CART) employed greedy search strategies, directly comparing all possible points in covariates. However, subsequent research showed that this biased towards selecting with more potential points. Therefore, unbiased recursive partitioning have been suggested QUEST, GUIDE, CTree, MOB) first select...
Abstract Objective Emergency surgery for acute bowel obstruction (ABO) is a common and occasionally technically demanding procedure, requiring both surgical skill strategic planning. The risk entailed in teaching residents during ABO has not been defined or investigated detail to date. It the aim of this study reveal whether ABO, performed by resident surgeons under supervision, safe feasible. Design A retrospective analysis was conducted all emergency surgeries between 2009 2023 at...
Background/Objectives: This study was conducted to determine whether a structured clinical pathway can help safely implement minimally invasive surgery (MIS) as the standard approach in for acute bowel obstruction (ABO). Methods: A prospective analysis performed on consecutive patients undergoing MIS ABO at single center 2021 and 2022. Prior onset, treatment defined apply all patients. The rate of success patient-, surgeon- outcome-specific parameters with focus complication conversion rates...
Intraoperative fluid therapy is regularly used in patients undergoing cardiac surgery procedures with cardiopulmonary bypass (CPB). Although administration has several advantages, it unavoidably leads to hemodilution. The hemodilution may further influence the interpretation of concentration-based laboratory parameters like hemoglobin (Hgb), platelet count (PLT) or prothrombin time (PT). These all are commonly guide blood product substitution. To assess impact dilution on these values, we...
While circular data occur in a wide range of scientific fields, the methodology for distributional modeling and probabilistic forecasting response variables is rather limited. Most existing methods are built on framework generalized linear additive models, which often challenging to optimize interpret. Therefore, we suggest regression trees random forests as an intuitive alternative approach that relatively easy fit. Building previous ideas means, both yielding forecasts based von Mises...