A5043191100- Cardiac Arrest and Resuscitation
- Electrolyte and hormonal disorders
- Neuroscience of respiration and sleep
- Clinical Nutrition and Gastroenterology
- Cancer, Hypoxia, and Metabolism
- Blood transfusion and management
- Nutrition and Health in Aging
- Renal function and acid-base balance
- Anesthesia and Sedative Agents
- Intravenous Infusion Technology and Safety
- Cannabis and Cannabinoid Research
- Criminal Law and Policy
- Heme Oxygenase-1 and Carbon Monoxide
- Criminal Law and Evidence
- Pulmonary Hypertension Research and Treatments
- Diet and metabolism studies
- Heart Rate Variability and Autonomic Control
- Respiratory Support and Mechanisms
- Muscle metabolism and nutrition
- Nitric Oxide and Endothelin Effects
- Cardiovascular and exercise physiology
- Heart Failure Treatment and Management
- Potassium and Related Disorders
- Clinical Laboratory Practices and Quality Control
Universität Innsbruck
2021-2025
Innsbruck Medical University
2021-2025
Tirol Kliniken
2024
Max Planck Society
1992
Max Planck Institute for the Study of Crime, Security and Law
1992
Background/Objectives: The urea-to-creatinine ratio (UCR) serves as a biochemical marker for catabolism in the intensive care unit (ICU). UCR increases mainly due to an elevated urea generation from increased protein metabolism. This study aimed evaluate impact of intake on progression ICU patients. Methods: inclusion criteria this retrospective, single-center analysis required stay at least 14 days without requirement renal replacement therapy (n = 346 patients). Patients were grouped based...
Abstract Desflurane, isoflurane and sevoflurane, three halogenated ethers, are commonly used inhaled anesthetics, both in the operating room intensive care unit (ICU). The potency dosage of these drugs is expressed by MAC value (minimum alveolar concentration). Their interaction with hemoglobin its affinity for oxygen, best described oxygen dissociation curve (ODC), has already been investigated, conflicting results. Altered many factors, ODC can be shifted to left or right, therefore...
5-Hydroxymethylfurfural (5-HMF) is known to increase hemoglobin oxygen affinity (Hb–O2 affinity) and induce a left shift of the dissociation curve (ODC). It under investigation as therapeutic agent in sickle cell anemia conditions where pulmonary uptake deteriorated or limited (e.g., various clinical altitude exposure). The combination 5-HMF α-ketoglutaric acid (αKG) commercially available nutritional supplement. To further elucidate dose effects, ODCs were measured vitro venous whole blood...
Inhalational prostacyclins act as strong vasodilators, potentially improving oxygenation by reducing shunt fraction and ventilation-perfusion mismatch. As prostacyclin receptors are known to be present on human erythrocytes, possible direct effects hemoglobin oxygen transport were further explored examining the sole in vitro influence of (Hb-O2) affinity. Venous blood samples from 20 healthy volunteers exposed supramaximal doses epoprostenol, iloprost, compared with control. By...
Hemoglobin‑oxygen (Hb-O
The affinity of hemoglobin (Hb) to oxygen (O
Intraoperative fluid therapy is regularly used in patients undergoing cardiac surgery procedures with cardiopulmonary bypass (CPB). Although administration has several advantages, it unavoidably leads to hemodilution. The hemodilution may further influence the interpretation of concentration-based laboratory parameters like hemoglobin (Hgb), platelet count (PLT) or prothrombin time (PT). These all are commonly guide blood product substitution. To assess impact dilution on these values, we...