A5002821123- Cancer survivorship and care
- Breast Lesions and Carcinomas
- Breast Cancer Treatment Studies
- BRCA gene mutations in cancer
- Cancer and Skin Lesions
- Global Cancer Incidence and Screening
- Advanced Breast Cancer Therapies
- Systemic Sclerosis and Related Diseases
- Colorectal Cancer Screening and Detection
- Estrogen and related hormone effects
- AI in cancer detection
- Hypothalamic control of reproductive hormones
- Menopause: Health Impacts and Treatments
- Cardiovascular Disease and Adiposity
- Reproductive System and Pregnancy
- Ovarian cancer diagnosis and treatment
- Ovarian function and disorders
- Systemic Lupus Erythematosus Research
- Genomic variations and chromosomal abnormalities
- Biomedical Text Mining and Ontologies
- Health and Wellbeing Research
- Family Support in Illness
- Mobile Health and mHealth Applications
- Autopsy Techniques and Outcomes
- Pelvic floor disorders treatments
KU Leuven
2019-2025
AZ Sint-Blasius
2023-2025
Universitair Ziekenhuis Leuven
2021-2024
Breast cancer survivorship is often associated with a negative impact on sexual function and well-being. Given that well-being contributes to quality of life-including for breast survivors-it important address survivors' worries during the treatment process. This study explored factors contribute changes in functioning after diagnosis otherwise healthy patients. Narrative qualitative using thematic analysis. We included 25 survivors without severe comorbidities individual interviews (N = 16)...
Abstract Background Registration and coding of cause death is prone to error since determining the exact underlying condition leading directly challenging. In this study, causes from certificates were compared patients’ medical files interpreted by experts at University Hospitals Leuven (UHL), assess concordance between sources its impact on cancer survival assessment. Methods Breast patients treated UHL (2009–2014) (follow-up until December 31st 2016) included in study. Cause was obtained...
Abstract Background Due to the lowering of circulating estrogens symptoms genitourinary syndrome menopause (GSM) may arise with premenopausal breast cancer patients who become menopausal due treatment. Clinical signs GSM are i.a. vaginal dryness, dyspareunia, loss libido, dysfunction arousal and/or orgasm: this negatively impact health, sexual activity and quality life. The composition function microbiome also change changes gonadal hormones during transition. This contribute discomfort...
Abstract Introduction: Currently, patients with luminal metastatic breast cancer receive a CDK4/6 inhibitor in combination endocrine therapy as first or second line of treatment. When tumors become resistant to the inhibitors, treatment alpelisib (PI3K inhibitor) an agent can be next option if activating PIK3CA mutation is confirmed (cfr. SOLAR-1 trial). However, limited data available after inhibitors BYLieve trial) and even less about later lines therapy. Therefore, we aim investigate...
Vaginal dehydroepiandrosterone for the treatment of vaginal atrophy in breast cancer survivors is a common problem survivors, but often remains undiscussed with health care professional. oestrogens are standard treatment, yet this quite controversial survivors. (DHEA) appears to be promising alternative. PubMed was screened clinical trials on offering local DHEA Only 2 published articles, both covering 1 randomized double-blind controlled trial, were found. In that study, 443 participants...
A 53-year-old North African woman presented with a longstanding history of ulcerations the right breast. Physical examination showed (Fig. 1 subfigure) an ulcer 1.5 cm in outer inferior quadrant, another smaller areolar and discharging sinus tract inframammary sulcus. Apart from female genital mutilation, her past medical was negative. Laboratory work up essentially normal, culture ulcers were taken. Mammography infra-areolar skin retraction, associated irregular, high density distortion...
Abstract Background and objective: Invasive micropapillary carcinoma (IMPC) of the breast is a special variant with unique morphology. Data about long-term outcome are conflicting reports on stromal tumor infiltrating lymphocytes (sTILs) their correlation prognosis scarce. In this retrospective cohort study we aimed to describe clinical pathological features IMPC, including sTILs assessment immunohistochemistry studies, outcome. Materials methods: Patients stage I-III IMPC (pure mixed forms)...
Voor elke zorgprofessional die vertrouwd wil raken met thoracale goiters, hashimotothyreoïditis, leydigcelhyperplasie en thyreotrope adenomen van de hypofyse, biedt dit e-book een bruikbare collectie op het gebied endocrinologie. Al deze artikels verschenen in 2021 Tijdschrift voor Geneeskunde Gezondheidszorg hebben hoog actualiteitsgehalte. Casuïstiek wordt afgewisseld overzichten, verrijkt illustrerende […]
Abstract Introduction: Flat epithelial atypia (FEA), classical lobular neoplasia (LN), papillary lesions (PL), radial scars (RS) and atypical ductal hyperplasia (ADH) are of uncertain malignant potential in the breast, which described as B3 B classification system European Working Group for Breast Cancer Screening Pathology. Current standard management on core needle biopsy (CNB) or vacuum assisted (VAB), is wide local excision (WE). However, recent consensus-based guidelines no longer...
Abstract Introduction Accurate information on cause of death is essential for correct breast cancer-specific mortality assessment. However, registration and coding prone to error since determining the exact underlying condition related challenging. In this study, an expert review medical files was done determine principal cancer patients a Belgian tertiary hospital. The retrieved compared certificate assess concordance between both sources. Secondly, impact discordant reporting...
Leydig cell hyperplasia: an atypical cause of postmenopausal hyperandrogenism We present a case 64-year old patient with new onset hirsutism, acne and clitoromegaly. Her medical history includes non-secreting adrenal incidentaloma. Biochemical evaluation withheld elevated testosterone normal dehydroepiandrosterone sulphate (DHEAS). Other biochemical tests were imaging was unaltered. Imaging the ovaries unremarkable. Due to DHEAS, ovarian etiology suspected, for which bilateral oophorectomy...
Lupus mastitis Systemic lupus erythematosus (SLE) infrequently presents itself as panniculitis. In panniculitis the subcutaneous fat tissue is involved in inflammatory process. again a rare variant of panniculitis, probably caused by an immune-mediated literature on topic we can find 30 cases men and women. may present like breast lesion suspected to be malignant, clinically radiologically. differential diagnosis consider cancer, panniculitis-like T-cell lymphoma (SPTL) diabetes mastopathy....