- Magnesium Alloys: Properties and Applications
- Corrosion Behavior and Inhibition
- Aluminum Alloys Composites Properties
- Herpesvirus Infections and Treatments
- T-cell and B-cell Immunology
- Thermodynamic properties of mixtures
- Chemical and Physical Properties in Aqueous Solutions
- Analytical Chemistry and Chromatography
- Monoclonal and Polyclonal Antibodies Research
- Photosynthetic Processes and Mechanisms
- Immune Cell Function and Interaction
- Mitochondrial Function and Pathology
- Photoreceptor and optogenetics research
- Metabolomics and Mass Spectrometry Studies
- Aluminum Alloy Microstructure Properties
- Mass Spectrometry Techniques and Applications
- Lung Cancer Treatments and Mutations
- Toxin Mechanisms and Immunotoxins
- Plant biochemistry and biosynthesis
- Phase Equilibria and Thermodynamics
- Light effects on plants
- Ocular and Laser Science Research
- Ionic liquids properties and applications
- Orthopaedic implants and arthroplasty
- Electrodeposition and Electroless Coatings
Shanghai East Hospital
2025
Shandong Normal University
2022-2024
Xiangnan University
2024
Zhongnan Hospital of Wuhan University
2024
Wuhan University
2024
Hua Medicine (China)
2024
Shenzhen Institutes of Advanced Technology
2024
Chinese Academy of Sciences
2024
Harbin Medical University
2021-2023
Second Affiliated Hospital of Harbin Medical University
2021-2023
Lipidomics is a significant way to understand the structural and functional roles that lipids play in biological systems. Although many mass spectrometry (MS)-based lipidomics strategies have recently achieve remarkable results, vivo, situ, microscale for small organisms cells not yet been obtained. In this article, we report novel methodology investigation of using biocompatible surface-coated probe nanoelectrospray ionization (BSCP-nanoESI-MS). A solid-phase microextration (SPME) prepared,...
Herpes simplex virus 1 (HSV-1) remodels nuclear membranes during egress. Although the UL31 and UL34 proteins control nucleocapsid transit in infected cells, molecular interactions required for their function are unclear. Here we report that γ134.5 gene product of HSV-1 facilitates release to cytoplasm through bridging UL31/UL34 complex, cellular p32, protein kinase C. Unlike wild-type virus, an HSV mutant devoid or its amino terminus is crippled viral growth release. This attributable a...
Lipids are important structural components of biological systems, and lipid C═C locations play roles in their biophysical biochemical properties. Rapid, vivo, situ, microscale lipidomics investigation (including precise identification isomers) specimen has great potential for clinical diagnosis, studies, biomarker discovery. Here we report a novel methodology by coupling Paternò-Büchi (PB) reaction with surface-coated probe nanoelectrospray ionization mass spectrometry (SCP-nanoESI-MS)...
We herein report an efficient and green aerobic radical cascade reaction of o -vinylphenylisocyanides with thiols to access a broad range 2-thio-substituted quinolines without the need for additional catalysts or oxidants.
Magnesium imbalances commonly exist in septic patients. However, the association of serum magnesium levels with mortality patients remains uncertain. Herein, we elucidated between and all-cause from American Chinese cohorts by analyzing data 9099 Medical Information Mart for Intensive Care-IV (MIMIC-IV) database 1727 a university-affiliated hospital' intensive care unit China. Patients both were categorized into five groups based on quintiles MIMIC-IV dataset. higher exhibited an increased...
We herein report a divergent synthesis of 2-CF₃ substituted quinolines and indoles via photoredox radical trifluoromethylation ortho-vinylphenylisocyanides. This mild green protocol offers broad substrate scope good...
Activity coefficients for the NaI + maltose water system at 298.15K were determined by an electrochemical method. The Gibbs energy interaction parameter (gES) and salting constant (kS) have also been calculated. Infinite dilution apparent molar volumes (VΦ,S) in aqueous solution those (VΦ,E) from density measurements as well volumetric parameters. results are discussed terms of structural model properties anions.
Herpes simplex virus 1 (HSV-1) is the most prevalent human and causes global morbidity because able to infect multiple cell types. Remarkably, HSV infection switches between lytic latent cycles, where T cells play a critical role. However, precise way of virus-host interactions incompletely understood. Here we report that HSV-1 productively infected Jurkat T-cells inhibited antigen-induced receptor activation. We discovered HSV-1-encoded Us3 protein interrupted TCR signaling interleukin-2...
AZ91 magnesium alloys modified by Er and Ce are fabricated (referred to as AZErCe) their stress corrosion cracking (SCC) behaviors studied slow strain rate tensile (SSRT) method in air, humid atmosphere with without chloride. The addition of promotes the formation Al 3 11 phase reduces both size volume fraction β‐phase. AZErCe possess improved resistance passivation characteristic compared due reduced micro‐galvanic more protective films. SSRT tests demonstrate that joint effectively improve...
In this paper, the corrosion residual strength of AZ91D magnesium alloy in presence sulfate-reducing bacteria is studied. experiments, chemical composition film was analyzed by a scanning electron microscope with energy dispersive X-ray spectroscopy. addition, series instruments, such as electronic microscope, pH-meter and an AG-10TA materials test machine, were applied to record morphology product, fracture texture mechanical properties alloy. The experiments show that (SRB) play important...
Abstract Optogenetics employs light to manipulate cellular events such as activation of molecular channels, signaling molecules, and gene transcription, by transfection with engineered light‐sensitive proteins. In the last decade, great progresses in life science have been made optogenetics, but limits its further medical applications. this study, it is reported that a short flash femtosecond‐laser stimulation can directly activate extracellular signal‐regulated kinase (ERK), an essential...
Abstract To improve the corrosion and mechanical properties of AM50 magnesium alloy, different amounts rare earth element gadolinium were used. The microstructure, evaluated by X-ray diffraction, scanning electron microscopy, energy dispersive spectroscopy, electrochemical stretch methods. results indicate that, with Gd addition, amount Al 2 3 phase increased while β -Mg 17 12 decreased. Due to grain alloy was significantly refined, which improved its tensile strength. Further, decrease in...