Yaohui Liu

ORCID: 0000-0002-0973-097X
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Research Areas
  • Magnesium Alloys: Properties and Applications
  • Corrosion Behavior and Inhibition
  • Aluminum Alloys Composites Properties
  • Herpesvirus Infections and Treatments
  • T-cell and B-cell Immunology
  • Thermodynamic properties of mixtures
  • Chemical and Physical Properties in Aqueous Solutions
  • Analytical Chemistry and Chromatography
  • Monoclonal and Polyclonal Antibodies Research
  • Photosynthetic Processes and Mechanisms
  • Immune Cell Function and Interaction
  • Mitochondrial Function and Pathology
  • Photoreceptor and optogenetics research
  • Metabolomics and Mass Spectrometry Studies
  • Aluminum Alloy Microstructure Properties
  • Mass Spectrometry Techniques and Applications
  • Lung Cancer Treatments and Mutations
  • Toxin Mechanisms and Immunotoxins
  • Plant biochemistry and biosynthesis
  • Phase Equilibria and Thermodynamics
  • Light effects on plants
  • Ocular and Laser Science Research
  • Ionic liquids properties and applications
  • Orthopaedic implants and arthroplasty
  • Electrodeposition and Electroless Coatings

Shanghai East Hospital
2025

Shandong Normal University
2022-2024

Xiangnan University
2024

Zhongnan Hospital of Wuhan University
2024

Wuhan University
2024

Hua Medicine (China)
2024

Shenzhen Institutes of Advanced Technology
2024

Chinese Academy of Sciences
2024

Harbin Medical University
2021-2023

Second Affiliated Hospital of Harbin Medical University
2021-2023

Lipidomics is a significant way to understand the structural and functional roles that lipids play in biological systems. Although many mass spectrometry (MS)-based lipidomics strategies have recently achieve remarkable results, vivo, situ, microscale for small organisms cells not yet been obtained. In this article, we report novel methodology investigation of using biocompatible surface-coated probe nanoelectrospray ionization (BSCP-nanoESI-MS). A solid-phase microextration (SPME) prepared,...

10.1021/acs.analchem.8b01218 article EN Analytical Chemistry 2018-04-30

Herpes simplex virus 1 (HSV-1) remodels nuclear membranes during egress. Although the UL31 and UL34 proteins control nucleocapsid transit in infected cells, molecular interactions required for their function are unclear. Here we report that γ134.5 gene product of HSV-1 facilitates release to cytoplasm through bridging UL31/UL34 complex, cellular p32, protein kinase C. Unlike wild-type virus, an HSV mutant devoid or its amino terminus is crippled viral growth release. This attributable a...

10.1128/jvi.01392-16 article EN Journal of Virology 2016-09-15

Lipids are important structural components of biological systems, and lipid C═C locations play roles in their biophysical biochemical properties. Rapid, vivo, situ, microscale lipidomics investigation (including precise identification isomers) specimen has great potential for clinical diagnosis, studies, biomarker discovery. Here we report a novel methodology by coupling Paternò-Büchi (PB) reaction with surface-coated probe nanoelectrospray ionization mass spectrometry (SCP-nanoESI-MS)...

10.1021/acs.analchem.8b05803 article EN Analytical Chemistry 2019-03-05

We herein report an efficient and green aerobic radical cascade reaction of o -vinylphenylisocyanides with thiols to access a broad range 2-thio-substituted quinolines without the need for additional catalysts or oxidants.

10.1039/d2qo01371a article EN Organic Chemistry Frontiers 2022-01-01

Magnesium imbalances commonly exist in septic patients. However, the association of serum magnesium levels with mortality patients remains uncertain. Herein, we elucidated between and all-cause from American Chinese cohorts by analyzing data 9099 Medical Information Mart for Intensive Care-IV (MIMIC-IV) database 1727 a university-affiliated hospital' intensive care unit China. Patients both were categorized into five groups based on quintiles MIMIC-IV dataset. higher exhibited an increased...

10.1002/mco2.713 article EN cc-by MedComm 2024-09-17

We herein report a divergent synthesis of 2-CF₃ substituted quinolines and indoles via photoredox radical trifluoromethylation ortho-vinylphenylisocyanides. This mild green protocol offers broad substrate scope good...

10.1039/d4qo02105c article EN Organic Chemistry Frontiers 2024-12-13

Activity coefficients for the NaI + maltose water system at 298.15K were determined by an electrochemical method. The Gibbs energy interaction parameter (gES) and salting constant (kS) have also been calculated. Infinite dilution apparent molar volumes (VΦ,S) in aqueous solution those (VΦ,E) from density measurements as well volumetric parameters. results are discussed terms of structural model properties anions.

10.1021/je700366w article EN Journal of Chemical & Engineering Data 2007-11-27

Herpes simplex virus 1 (HSV-1) is the most prevalent human and causes global morbidity because able to infect multiple cell types. Remarkably, HSV infection switches between lytic latent cycles, where T cells play a critical role. However, precise way of virus-host interactions incompletely understood. Here we report that HSV-1 productively infected Jurkat T-cells inhibited antigen-induced receptor activation. We discovered HSV-1-encoded Us3 protein interrupted TCR signaling interleukin-2...

10.1074/jbc.m115.646422 article EN cc-by Journal of Biological Chemistry 2015-04-24

AZ91 magnesium alloys modified by Er and Ce are fabricated (referred to as AZErCe) their stress corrosion cracking (SCC) behaviors studied slow strain rate tensile (SSRT) method in air, humid atmosphere with without chloride. The addition of promotes the formation Al 3 11 phase reduces both size volume fraction β‐phase. AZErCe possess improved resistance passivation characteristic compared due reduced micro‐galvanic more protective films. SSRT tests demonstrate that joint effectively improve...

10.1002/adem.201700021 article EN Advanced Engineering Materials 2017-04-05

In this paper, the corrosion residual strength of AZ91D magnesium alloy in presence sulfate-reducing bacteria is studied. experiments, chemical composition film was analyzed by a scanning electron microscope with energy dispersive X-ray spectroscopy. addition, series instruments, such as electronic microscope, pH-meter and an AG-10TA materials test machine, were applied to record morphology product, fracture texture mechanical properties alloy. The experiments show that (SRB) play important...

10.3390/ma7107118 article EN Materials 2014-10-21

Abstract Optogenetics employs light to manipulate cellular events such as activation of molecular channels, signaling molecules, and gene transcription, by transfection with engineered light‐sensitive proteins. In the last decade, great progresses in life science have been made optogenetics, but limits its further medical applications. this study, it is reported that a short flash femtosecond‐laser stimulation can directly activate extracellular signal‐regulated kinase (ERK), an essential...

10.1002/lpor.201700137 article EN Laser & Photonics Review 2018-05-14

Abstract To improve the corrosion and mechanical properties of AM50 magnesium alloy, different amounts rare earth element gadolinium were used. The microstructure, evaluated by X-ray diffraction, scanning electron microscopy, energy dispersive spectroscopy, electrochemical stretch methods. results indicate that, with Gd addition, amount Al 2 3 phase increased while β -Mg 17 12 decreased. Due to grain alloy was significantly refined, which improved its tensile strength. Further, decrease in...

10.1515/phys-2016-0049 article EN cc-by-nc-nd Open Physics 2016-01-01
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