- Dementia and Cognitive Impairment Research
- Nutrition and Health in Aging
- Frailty in Older Adults
- Nutritional Studies and Diet
- Ophthalmology and Visual Impairment Studies
- Retinal Imaging and Analysis
- Geriatric Care and Nursing Homes
- Glaucoma and retinal disorders
- Health Systems, Economic Evaluations, Quality of Life
- Balance, Gait, and Falls Prevention
- Intergenerational Family Dynamics and Caregiving
- Retinal and Optic Conditions
- Diet and metabolism studies
- Family Caregiving in Mental Illness
- Vitamin K Research Studies
- Retinal Diseases and Treatments
- Palliative Care and End-of-Life Issues
- Retinal Development and Disorders
- Health, Medicine and Society
- Healthcare Systems and Practices
- Alzheimer's disease research and treatments
- Older Adults Driving Studies
- Aging, Elder Care, and Social Issues
- Functional Brain Connectivity Studies
- Visual perception and processing mechanisms
Université de Montréal
2016-2025
Institut Universitaire de Gériatrie de Montréal
2015-2025
Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal
2019-2025
Directorate-General Joint Research Centre
2001-2021
Université du Québec à Montréal
2020
Université Paris Nanterre
2016
Université Paris Cité
2009
Merck Serono (Switzerland)
2009
Centre Hospitalier de l’Université de Montréal
2009
The University of Kitakyushu
2002
Optimal nutrition is essential for general well being, maintenance of physical and functional capacities prevention chronic disease in the elderly. The 5-year longitudinal study, NuAge, was designed to assess pivotal role on cognitive status, autonomy social functioning. A cohort 1793 men women, selected from three age groups (68–72, 73–77, 78–82) at recruitment, has been followed annually since 2003–2004. plurimethodological approach, including basic, clinical, epidemiologic, research used....
ABSTRACT Background: Frailty is a complex health state of increased vulnerability associated with adverse outcomes such as disability, falls, hospitalization, and death. Along physical impairments, cognition quality life may be affected in frail older adults. Yet, evidence still lacking. The aim this study was to compare non-frail adults on physical, cognitive, psychological dimensions. Methods: Thirty-nine 44 elders were compared several measures capacity, cognition, life. status based...
The purpose of this experimental study was to test the efficacy a psychoeducational individual program conceived facilitate transition caregiver role following diagnosis Alzheimer disease in relative.Caregivers were recruited memory clinics and randomized an group (n = 62) or control 49) receiving usual care. Eligible participants-primary caregivers relative diagnosed with past 9 months-were assessed blindly before randomization, at end (post-test), 3 months later (follow-up) on different...
To date, few studies have examined the experience of spouse caregivers living with a person early-onset dementia. Moreover, support resources are offered to these family and fewer still tailored their unique trajectory. The aim this qualitative study was document lived young patients in order inform development professional reality. A sample 12 spouses persons diagnosed dementia before age 65 participated semistructured interviews. Six themes emerged from caregiver trajectories, namely,...
Purpose: Physical exercise and cognitive training have been shown to enhance cognition among older adults. However, few studies looked at the potential synergetic effects of combining physical in a single study. Prior trials on combined led interesting yet equivocal results. The aim this study was examine interventions fitness neuropsychological performance healthy Methods: Seventy-six participants were randomly assigned one four combinations using 2×2 factorial design. intervention mixed...
Only a limited number of studies have investigated the decline discrete cognitive domains as individuals progress from mild impairment (MCI) to dementia.Thus, goal this longitudinal study was evaluate changes underway during years preceding diagnosis probable Alzheimer's disease (AD), and compare these those found in MCI participants who do not dementia.Participants were compared function whether they later converted AD (n = 47) or 74).Cognitive change assessed prior conversion year, using...
Purpose.: To examine the extent of mobility limitations in patients with age-related macular degeneration (AMD), glaucoma, or Fuchs' corneal dystrophy compared that a control group older adults good vision. Methods.: Two hundred seventy-two (68 AMD, 49 dystrophy, 82 and 73 controls) from ophthalmology clinics Maisonneuve-Rosemont Hospital (Montreal, Canada) participated cross-sectional study September 2009 until February 2011. Control who had normal visual acuity fields were recruited same...
Purpose: The purpose of this study is to examine whether patients with age-related eye diseases, like macular degeneration (AMD), glaucoma, or Fuchs corneal dystrophy, are more likely show signs depression compared a control group older adults good vision, and determine reduced mobility mediates these relationships. Methods: We recruited 315 eligible (81 AMD, 55 Fuchs, 91 88 controls) from the ophthalmology clinics Montreal hospital September 2009 until December 2011. Depressive symptoms...
The growing interest in early-onset dementia has attracted attention to the situation and experiences of caregiver, most often spouse. Several qualitative studies on caregiving spouses have underlined importance feeling loss, change role reported by spouses, strategies used protect person with dementia, all which raise question relational dynamics at play these dyads. present study 16 couples examines each partner, as well kinds interactions taking place within dyad how they evolved since...
Purpose.: To examine whether patients with age-related macular degeneration (AMD), glaucoma, or Fuchs corneal dystrophy report limiting their activity due to a fear of falling as compared control group older adults good vision. Methods.: We recruited 345 (93 AMD, 57 Fuchs, 98 and 97 controls) from the ophthalmology clinics Maisonneuve-Rosemont Hospital (Montreal, Canada) participate in cross-sectional study September 2009 until July 2012. Control who had normal visual acuity field were same...
The interRAI suite of assessment instruments can provide valuable information to support person-specific care planning across the continuum care. Comprehensive clinical is collected with these instruments, including disease diagnoses. In Canada, data holdings represent some largest repositories in country for persons neurological conditions. This study examined accuracy diagnostic captured by designed use home care, long-term and mental health settings as compared national administrative...
Purpose: To determine the relationship between fine particulate matter (PM2.5) and ocular outcomes such as visual impairment age-related eye disease. Methods: Baseline data were used from Canadian Longitudinal Study on Aging. The Comprehensive Cohort consisted of 30,097 adults ages 45 to 85 years. Annual mean PM2.5 levels (µg/m3) for each participant's postal code estimated satellite data. Ozone, sulfur dioxide, nitrogen dioxide also estimated. Binocular presenting acuity was measured using...
This study aimed at evaluating face and content validity, feasibility reliability of process quality indicators developed previously in the United States or other countries. The can be used to evaluate care services for vulnerable older adults affected by cognitive impairment dementia within an integrated service system Quebec, Canada.A total 33 clinical experts from three major urban centres Quebec formed a panel representing two medical specialties (family medicine, geriatrics) seven...
The first signs of cognitive impairment in the elderly generally elicit much concern among family members. Reactions run from denial to active search for information. Some families manage set up relatively well-organized networks informal support help both caregivers and relatives. However, little is known about processes underlying different pathways that follow at onset Alzheimer-type dementia To gain a better understanding barriers care early caregiving career, illness diagnosis, authors...
<i>Background:</i> Amnestic mild cognitive impairment (aMCI) is considered a transition stage between normal aging and Alzheimer’s disease (AD). Two main clinical subtypes of aMCI have been identified: (1) single-domain (aMCI-SD), with isolated episodic memory impairments, (2) multiple-domain (aMCI-MD), impairments deficits in one or more other domains. <i>Aims:</i> To map the pattern gray matter (GM) atrophy associated aMCI-SD, aMCI-MD AD. <i>Methods:</i>...
Though advances in knowledge and diagnostics make it possible today to identify persons with early-onset dementia or a related cognitive disorder much sooner, little is known about the support needs of family caregivers these persons. The aim this study was document unmet specific group caregivers. This essential open avenues for development innovative interventions professional services tailored their needs. conducted using mixed research design. Participants were 32 50s recruited through...
To determine whether people with age-related eye disease have lower cognitive scores than healthy vision.A hospital-based cross-sectional study was performed in which 420 aged 65 and older from the ophthalmology clinics at Maisonneuve-Rosemont Hospital (Montreal, Canada) were recruited who had macular degeneration (AMD), Fuch's corneal dystrophy, or glaucoma. Patients AMD Fuchs to visual acuity better of worse 20/40 while patients glaucoma field their least -4 dB. Controls, same clinics, did...