A5034071037- Cutaneous Melanoma Detection and Management
- Cutaneous lymphoproliferative disorders research
- Nail Diseases and Treatments
- Nonmelanoma Skin Cancer Studies
- Autoimmune Bullous Skin Diseases
- Lymphoma Diagnosis and Treatment
- Leprosy Research and Treatment
- Cancer and Skin Lesions
- Psoriasis: Treatment and Pathogenesis
- Genetic and rare skin diseases.
- Fungal Infections and Studies
- Mycobacterium research and diagnosis
- Infectious Diseases and Tuberculosis
- Dermatology and Skin Diseases
- Dermatological diseases and infestations
- Systemic Sclerosis and Related Diseases
- Infectious Diseases and Mycology
- Drug-Induced Adverse Reactions
- Autoimmune and Inflammatory Disorders
- melanin and skin pigmentation
- Urticaria and Related Conditions
- Oral Health Pathology and Treatment
- Vascular Tumors and Angiosarcomas
- Tumors and Oncological Cases
- Skin Diseases and Diabetes
Ente Ospedaliero Ospedali Galliera
2016-2025
Istituto Clinico Sant'Ambrogio
2023
Medical University of Graz
2010-2020
Austrian Society of Dermatology and Venereology
2004-2016
Hospital Curry Cabral
2016
Centro Hospitalar de Lisboa Central
2016
University of Graz
2004-2015
University of Genoa
1999-2013
Ospedale Policlinico San Martino
2010-2013
Hospital Fernández
2011
Deep learning convolutional neural networks (CNN) may facilitate melanoma detection, but data comparing a CNN's diagnostic performance to larger groups of dermatologists are lacking.Google's Inception v4 CNN architecture was trained and validated using dermoscopic images corresponding diagnoses. In comparative cross-sectional reader study 100-image test-set used (level-I: dermoscopy only; level-II: plus clinical information images). Main outcome measures were sensitivity, specificity area...
Abstract Lichen planus (LP) is a chronic inflammatory and immune‐mediated disease that affects the skin, hair, nails mucous membranes. Although there broad clinical spectrum of lichen manifestations, skin oral cavity remain major sites involvement. A group European dermatologists with long‐standing interest expertise in has sought to define therapeutic guidelines for management patients LP. The features, diagnosis possible medications clinicians can use, order control disease, will be...
A new group of subcutaneous, natural killer (NK), NK/T-cell, and other cytotoxic T-cell lymphomas the skin has been recently described, some have included as distinct clinicopathologic entities in classification hematologic malignancies proposed by World Health Organization. In European Organization for Research Treatment Cancer cutaneous lymphomas, they would be classified either CD30- large lymphoma, small/medium pleomorphic or subcutaneous lymphoma. Precise prognostic features all them...
The ability to diagnose malignant skin tumours accurately and distinguish them from benign lesions is vital in ensuring appropriate patient management. Little known about the effects of mobile teledermatology services on diagnostic accuracy their appropriateness for tumour surveillance.To evaluate clinical dermoscopic image tele-evaluation screening.Over a 3-month period up three images were obtained 113 88 patients using phone camera. Dermoscopic taken with dermatoscope applied camera lens....
The histologic diagnosis of early mycosis fungoides (MF) is one the most vexing problems in dermatopathology. We reviewed histopathologic features 745 biopsy specimens from 427 patients (male:female = 277:150; median age, 52 years; range, 3-95 years) with (patch) lesions MF collected lymphoma database Department Dermatology Medical University Graz (Austria). In all patients, was established by clinicopathologic correlation. common pattern consisted a band-like or patchy lichenoid infiltrate...
The diagnosis of lupus erythematosus panniculitis (LEP) may be very difficult in cases which involvement the subcutaneous fat is only manifestation disease. main differential panniculitis-like T-cell lymphoma (SPTCL).We performed a retrospective study reviewing histopathologic features 11 biopsy specimens from nine patients with LEP (M : F = 2 7; median age: 48 years; range: 20-71 years).Histopathologically, all biopsies revealed lobular panniculitis, concomitant septal 82% them. Dermal...
Cutaneous infectious and inflammatory diseases may contain a significant number of CD30-positive cells, thus mimicking lymphomatoid papulosis (LyP) or anaplastic large cell lymphoma.We reviewed our cases non-neoplastic skin conditions with large, cells searched the literature for similar cases.A total 28 were included in study: Milker's nodule (n = 8), Herpes simplex virus infection 7), drug reaction 3), molluscum contagiosum nodular scabies 2), leishmaniasis 1), syphilis pernio ruptured...
Summary Background In 2007 the International Psoriasis Council proposed that palmoplantar pustulosis (PPP) should be considered a separate condition from psoriasis, despite presence of certain phenotypes common in both diseases. Objectives To describe and compare demographic clinical characteristics among patients with PPP plaque psoriasis. Methods This was retrospective case series study 2005 to 2010. The following data were obtained: age, sex, family history, smoking habits, nail...
Aims Aggressive epidermotropic cutaneous CD 8 + lymphoma is currently afforded provisional status in the WHO classification of lymphomas. An EORTC Workshop was convened to describe detail features this putative neoplasm and evaluate its nosological with respect other Methods results Sixty‐one cases were analysed at workshop; clinical details, often photographs, histological sections, immunohistochemical results, treatment patient outcome discussed recorded. Eighteen had distinct conformed...
Mobile teledermatology has recently been shown to be suitable for despite limitations in image definition preliminary studies. The unique aspect of mobile is that this system represents a filtering or triage system, allowing sensitive approach the management patients with emergent skin diseases.In study we investigated feasibility teleconsultation using new generation cellular phones pigmented lesions. 18 were selected consecutively Pigmented Skin Lesions Clinic Department Dermatology,...
The influence of phenotype and detection clonality on prognosis in early mycosis fungoides has never been addressed large studies.To correlate immunophenotype with clinical outcome.We analysed 73 biopsy specimens from 68 patients (stage Ia or Ib) at least 10 years follow up (or dead disease).Four phenotypic groups could be identified: group A (alpha/beta+ CD4+ CD8- TIA1-), 51 patients; median survival time 160 months; B CD4- CD8+ TIA1+), 195 C (alpha/beta- CD8+/- five 165 D two 130 months....
Cutaneous lymphomas expressing CD56, a neural cell adhesion molecule, are characterised in most cases by highly aggressive clinical course and poor prognosis. However, prognostic subsets within the CD56+ group have been difficult to identify due lack of uniform clinicopathological immunophenotypical criteria.A multicentre study was conducted Lymphoma Task Force European Organisation for Research Treatment Cancer define parameters establish diagnostic therapeutic guidelines haematological...
Summary We investigated the diagnostic agreement between teledermatology based on images from a mobile phone camera and face-to-face (FTF) dermatology. Diagnostic was assessed for two teledermatologists (TD) in comparison with FTF consultations 58 subjects. In almost three-quarters of cases (TD1: 71%; TD2: 76%), telediagnosis fully concordant diagnosis. Furthermore, diagnosed diseases were all same category 97%; 90%). If had been used remote triage, TD1 could have treated 53% subjects...
Most cases of intravascular large cell lymphoma have a B-cell phenotype, but rare T-cell and natural killer (NK)-cell variants been reported. We describe the clinicopathologic features 4 patients (M:F=3:1; age range: 63 to 87; median age: 65) with NK/T-cell lymphoma. The skin was site presentation in all (leg: 1 case; trunk: trunk extremities: 2 cases). Two had lesions confined skin; case concomitant involvement brain detected no further studies were carried out. Immunohistology showed...
Smartphones have overcome the limitations of image quality seen in older devices and opened a new field telemedicine called "mobile teledermatology". Technological advances need to reduce health service costs will strongly promote development telemedicine. For this reason, we evaluated concordance between store-and-forward mobile teledermatology classical face-to-face dermatological visit. We also measured time taken submit teleconsultation using smartphone. Before conventional visit,...
Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare cytotoxic of the skin presenting with histopathologic features simulating those lobular panniculitis. The presence neoplastic T-lymphocytes forming rim around individual fat cells in subcutaneous lobules, so-called "rimming" adipocytes, considered characteristic morphologic feature this type cutaneous lymphoma. In study we reviewed series 45 biopsy specimens primary and secondary B- lymphomas one myeloid leukemia involving...
Background: Primary cutaneous anaplastic large T‐cell lymphoma (PCALCL) is a well‐defined entity with prognostic differences from the nodal counterpart [nodal cell (NALCL)]. Several histological variants of NALCL have been characterized (common, lymphohistiocytic and small cell). However, studies on morphological PCALCLs are lacking. Methods: We analyzed retrospectively clinicopathologic features 66 biopsies 47 patients (M : F = 27 20; median age: 53 years; mean 51.8 range: 14–82) PCALCL, in...