A5017757167- Lymphoma Diagnosis and Treatment
- Endometrial and Cervical Cancer Treatments
- Cutaneous Melanoma Detection and Management
- Cutaneous lymphoproliferative disorders research
- Cancer and Skin Lesions
- Ovarian cancer diagnosis and treatment
- Sarcoma Diagnosis and Treatment
- CNS Lymphoma Diagnosis and Treatment
- Viral-associated cancers and disorders
- Cervical Cancer and HPV Research
- Genetic and rare skin diseases.
- Nonmelanoma Skin Cancer Studies
- Vascular Tumors and Angiosarcomas
- Fungal Infections and Studies
- Endometriosis Research and Treatment
- Uterine Myomas and Treatments
- Epigenetics and DNA Methylation
- Soft tissue tumor case studies
- Nail Diseases and Treatments
- Immunotherapy and Immune Responses
- Signaling Pathways in Disease
- Genomics and Chromatin Dynamics
- Gastric Cancer Management and Outcomes
- Autoimmune and Inflammatory Disorders
- Autoimmune Bullous Skin Diseases
University of Naples Federico II
2016-2025
Federico II University Hospital
2015-2025
Advanced Computer System (Italy)
2019-2020
Enel (Italy)
2020
Advanced Pharma
2015-2019
May Institute
2017
University of Foggia
2007
Institute of Molecular Pathology and Pathomorphology
2003-2006
Anti-programmed cell death 1 (PD1) is the first-choice treatment in patients with advanced cutaneous squamous carcinoma (cSCC), when curative options are unavailable. However, reliable biomarkers for patient selection still lacking. In this translational study, clinical annotations, tissue and liquid biopsies were acquired to investigate association between sustained objective responses transcriptional profiles, immune dynamics tumor peripheral blood samples, as well circulating cytokine...
The chemokine receptor CXCR4 and CD133, putative stem cell markers, were previously described in renal cancer (RCC). To evaluate the biological prognostic role of CD133 RCC expression was evaluated through qPCR immunoblotting human lines (786-O, A498, ACHN, CAKI-1, SN12C, TK10, UO31) patients biopsies. Renal cells surgical biopsies expressed functional while not detectable. then 240 immunohistochemistry. low 19.1% 59.6%; intermediate 20% 17.9%; high 60.8% 22.5% cases, respectively....
Abstract Melanoma is the most aggressive skin cancer; there no cure in advanced stages. Identifying molecular participants melanoma progression may provide useful diagnostic and therapeutic tools. FK506 binding protein 51 (FKBP51), an immunophilin with a relevant role developmental stages, highly expressed correlates aggressiveness therapy resistance. We hypothesized for FKBP51 invasive behaviour. promoted activation of epithelial-to-mesenchymal transition (EMT) genes improved cell migration...
A new family of angiogenic factors named endocrine-gland-derived vascular endothelial growth (EG-VEGF)/prokineticins (PK) have been recently described as predominantly expressed in steroidogenic tissues. Whether the normal and malignant epithelial prostate cells tissues express EG-VEGF/PK1 PK2 their receptors is still unknown. We studied expression (PK-R1 PK-R2) human involvement cancer. Using immunohistochemistry, Western blot, RT-PCR, we determined (NP) (PCa), cell primary cultures from...