- Pharmaceutical Practices and Patient Outcomes
- Pharmaceutical Economics and Policy
- Historical Medical Research and Treatments
- Biosimilars and Bioanalytical Methods
- Analytical Methods in Pharmaceuticals
- Chemical synthesis and alkaloids
- Drug Solubulity and Delivery Systems
- Adsorption, diffusion, and thermodynamic properties of materials
- Health and Medical Education
- Pharmaceutical industry and healthcare
- Crystallization and Solubility Studies
- History and advancements in chemistry
- Acute Lymphoblastic Leukemia research
- Regulation of Appetite and Obesity
- Historical and Scientific Studies
- Psychedelics and Drug Studies
- Pharmacological Effects and Assays
- Historical Studies in Science
- Nanoparticle-Based Drug Delivery
- Bioactive Compounds and Antitumor Agents
- Ethics and bioethics in healthcare
- Adipokines, Inflammation, and Metabolic Diseases
- Medical and Pharmaceutic Studies
- Pharmacogenetics and Drug Metabolism
- Free Radicals and Antioxidants
Universidad Autónoma del Estado de México
2014-2024
Universidad Autónoma Metropolitana
2017
Abstract Thirty million people worldwide consume each day nonsteroidal anti‐inflammatory drugs (NSAIDs), a heterogeneous group of pharmaceuticals used for its analgesic, antipyretic, and properties. Recent studies report high NSAID concentrations in wastewater treatment plant effluents, surface, ground, drinking water, sediments. NSAIDs are also known to induce toxicity on aquatic organisms. However, natural ecosystems is not usually the result exposure single substance but mixture toxic...
Nanotechnology has been used for every single modality in the molecular imaging arena purposes. Synergic advantages can be explored when multiple modalities are combined with respect to modalities. Multifunctional nanoparticles have large surface areas, where functional moieties incorporated, including ligands site-specific targeting and radionuclides, which detected create 3D images. Recently, radiolabeled individual properties attracted great interest regarding their use multimodality...
One of the factors that has increased incidence and worse prognosis breast cancer is obesity. In this condition, high amounts leptin are secreted, which have proliferative, mitogenic, antiapoptotic, proinflammatory activity may be antagonistic to treatment with tamoxifen, considered first choice. The modulation evaluation receptor expression in presence tamoxifen stimuli was performed cell lines MCF 7, MDA MB 231 HCC 1937 as a model initial approach for study subtypes their behavior action...
En 1968 la Organizacion Mundial de Salud afirmo que la brucelosis era responsable mas enfermedades, miserias y perdidas economicas cualquier otra enfermedad animal conocida afecte a los humanos. Esta ejemplifica la falta interaccion sectores salud publica y veterinaria, haciendo esta infeccion una las zoonosis mas frecuentes en el mundo, con especial importancia en paises mediterraneos Europa y Africa, Oriente Medio, America Central del Sur, Asia Central, la India Mexico.
La selección de un polímero para mejorar la velocidad disolución fármaco dentro una fórmula farmacéutica implica el uso múltiples pruebas que encarecen proceso selección, por requerir técnicas alta especialización; lo opuesto es método reducido basado en estudios calorimétricos y disolución, ayude preliminar los materiales, sin altas inversiones monetarias o tiempo. En este trabajo se realizó preselección acarreador, con potencial ser usado desarrollo dispersiones sólidas clorhidrato...
Under thermal conditions perezone, a sesquiterpene quinone, forms an equimolar amount of a- and β-pipitzol through intermolecular cycloaddition reaction. Computational calculations at M06-2x/6-311++G(2d,2p) level theory the transition states associated reaction paths allow justifying experimental observations. Only exo adducts are observed experimentally, which is in line with calculated energy difference 6.5 kcal/mol between endo adducts. Activation free was accurately predicted, those...
Background: Melt granulation (MG) is a simple operation involving uniform mixture of active ingredients with melted polymeric carrier. However, this process can also enhance drug’s biopharmaceutical properties by augmenting its dissolution rate and, thus, absorption. Purpose: By applying MG technology, current research focuses on developing co-processed ketoconazole higher aqueous than pure form. Methods: A measure how the type and proportion carriers affect crystallinity materials was...
Background: Melt granulation (MG) is a simple operation involving uniform mixture of active ingredients with melted polymeric carrier. However, this process can also enhance drug’s biopharmaceutical properties by augmenting its dissolution rate and, thus, absorption. Purpose: By applying MG technology, current research focuses on developing co-processed ketoconazole higher aqueous than pure form. Methods: A measure how the type and proportion carriers affect crystallinity materials was...
Antimicrobial peptides of higher organisms have been studied for the past 25 years, and their importance as components innate immunity is now well established. The essential simplicity chemical structure, along with lower likelihood developed resistance compared to conventional antibiotics, has made them attractive candidates development therapeutics. objective this review article describe current relevance, main mechanisms presented, uses antimicrobial new therapies in clinical area....
During the 19th century and first decades of 20th, scientific research in Mexico revolved mainly around study medicinal plants. This paper discusses instruments techniques used during this period by pharmacists their teaching activities. The function that was related to chemical analysis procedures accordance with European schools Pharmacy; main objective find alkaloids therapeutic utility within these interest development practice analytical chemistry fundamental eventually allowed...
Esta es una revisión del desarrollo histórico de la legislación en materia medicamentos genéricos México, con especial énfasis evolución Cuadro Básico Medicamentos desde 1975 hasta actualidad y Norma Oficial Mexicana 177 versiones 1998 2013. Se discute también el impacto que tienen estos insumos para salud economía nacional, puesto México está considerado como primer exportador América Latina. revisa uso prueba in vitro disolución herramienta necesaria tanto fase investigación desarrollo,...
<p>A finales del siglo XIX y principios XX, las ampolletas inyectables llegaron a México Estados Unidos con recibimientos distintos por parte de los farmacéuticos locales. Mientras que en la recepción fue favorable, fueron acogidas desconfianza, lo dio lugar diferencias importantes su desarrollo manufactura ambos países. El objetivo este trabajo es analizar divergencias similitudes tuvieron procesos introducción Unidos. Se busca mostrar adopción influenciada modelos terapéuticos...
<p>El presente trabajo analiza por primera vez las 39 tesis de la carrera Farmacia elaboradas los alumnos Escuela Nacional Medicina entre 1897 y 1917. Los trabajos abarcan principalmente temas relativos al análisis químico diversos tipos sustratos, estudios relacionados con plantas medicinales, aplicaciones bacteriológicas a procesos farmacéuticos, particularidades algunas formas farmacéuticas en menor medida aspectos legislación, historia ejercicio farmacéuticos. Las farmacia...
<h3>Abstract:</h3> In 1849 Johann Wilhelm Schaffner, a German naturalist trained in Darmstadt and renowned for his botanical contributions arrived Mexico. Three years later, the famous Mexican chemist Leopoldo Río de la Loza published first elemental analysis developed that country, applying it to pipitzahoic acid (perezone). The technique used was by Justus von Liebig 1831. However, application of not explored again Mexico until middle twentieth century, pushing back areas chemistry had...
Existen pocos estudios sobre farmacovigilancia (FV) y reacciones adversas a medicamentos (RAM) en México. El objetivo fue evaluar el efecto de un programa formación FV las actitudes profesionales sanitarios hospital público del Estado Se realizó este estudio 100 médicos enfermeras. diseñó cuestionario FV; se determinó su fiabilidad con coeficiente alfa Cronbach validez criterio por método Delphi administró. Posteriormente, necesidades detectadas, formación, aplicó los participantes nuevo...
Background: Melt granulation (MG) is a simple operation involving uniform mixture of active ingredients with melted polymeric carrier. However, this process can also enhance drug's biopharmaceutical properties by augmenting its dissolution rate and, thus, absorption. Purpose: By applying MG technology, current research focuses on developing co-processed ketoconazole higher aqueous than pure form. Methods: A measure how the type and proportion carriers affect crystallinity materials was...
Introducción: los fármacos clase II representan un alto porcentaje de las moléculas en fase investigación biomédica. Este grupo atrajo la últimos años, ya que su baja solubilidad acuosa condiciona absorción in vivo, lo plantea reto para tecnología farmacéutica. El diseño dispersiones sólidas (SD) es una técnica ha tenido éxito y se basa dispersión del fármaco acarreador polimérico, promoviendo el estado amorfo primero. Uno métodos obtención SD fusión, puede llevar a cabo equipos...