Jae-Geun Lee

ORCID: 0000-0002-1014-9939
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About
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Research Areas
  • Pluripotent Stem Cells Research
  • Zebrafish Biomedical Research Applications
  • Animal Genetics and Reproduction
  • Alzheimer's disease research and treatments
  • Neuroscience and Neuropharmacology Research
  • Autophagy in Disease and Therapy

Korea Research Institute of Bioscience and Biotechnology
2022-2024

Korea University of Science and Technology
2022

Amphibians and fish show considerable regeneration potential via dedifferentiation of somatic cells into blastemal cells. In terms dedifferentiation, in vitro cellular reprogramming has been proposed to share common processes with vivo tissue regeneration, although the details are elusive. Here, we identified cytoskeletal linker protein desmoplakin (Dsp) as a factor mediating both regeneration. Our analysis revealed that Dsp expression is elevated distinct intermediate during reprogramming....

10.1126/sciadv.abk1239 article EN cc-by-nc Science Advances 2022-10-28
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