A5080928633- Skin Protection and Aging
- Dermatology and Skin Diseases
- Urticaria and Related Conditions
- Genomics, phytochemicals, and oxidative stress
- melanin and skin pigmentation
- Dermatologic Treatments and Research
- Acne and Rosacea Treatments and Effects
- Nail Diseases and Treatments
- Contact Dermatitis and Allergies
- Allergic Rhinitis and Sensitization
- Wheat and Barley Genetics and Pathology
- Asthma and respiratory diseases
- Immune Cell Function and Interaction
- Autoimmune Bullous Skin Diseases
- Cervical Cancer and HPV Research
- Plant Disease Resistance and Genetics
- Cutaneous lymphoproliferative disorders research
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Laser Applications in Dentistry and Medicine
- Food composition and properties
- Mast cells and histamine
- Hepatitis B Virus Studies
- Phytochemicals and Antioxidant Activities
- Genetic and rare skin diseases.
- Hepatitis C virus research
Guangzhou Institute of Dermatology
2016-2025
Guangzhou Medical University
2017-2025
Tianjin University of Science and Technology
2024-2025
State Key Laboratory of Food Nutrition and Safety
2025
Guangzhou First People's Hospital
2023
Guangdong Academy of Medical Sciences
2023
Guangdong Provincial People's Hospital
2023
The University of Sydney
2023
Jimei University
2023
City University of Hong Kong
2023
Summary Polyploid wheats comprise four species: Triticum turgidum ( AABB genomes) and T. aestivum AABBDD ) in the Emmer lineage, timopheevii AAGG zhukovskyi AAGGA m A Timopheevi lineage. Genetic relationships between chloroplast genomes were studied to trace evolutionary history of species. Twenty‐five sequenced, 1127 plant accessions genotyped, representing 13 Aegilops The A. speltoides SS genome) diverged before divergence urartu AA ), tauschii DD species Sitopsis section. forms a...
Ultraviolet B (UVB) irradiation plays a key role in skin damage, which induces oxidative and inflammatory damages, thereby causing photoaging or photocarcinogenesis. Lycium barbarum polysaccharide (LBP), the most biologically active fraction of wolfberry, possesses significant antioxidative anti-inflammatory effects on multiple tissues. In present study, photoprotective potential underlying molecular mechanisms LBP against UVB-induced photo-damage were investigated immortalized human...
With the increasing number of diabetic patients in world, there is an urgent requirement to reduce incidence diabetes. It considered that a viable prophylactic treatment for type 2 diabetes mellitus starch digestibility and oxidative stress. In this study, novel slowly digested [pea (PS)-gingerol complex] was fabricated evaluate its vitro enzymatic antioxidant activities. Theoretical experimental analyses showed PS can encapsulate gingerols with long alkyl chains form starch–gingerol...
Cryptochromes (CRYs) are blue light receptors important for plant growth and development. Comprehensive information on monocot CRYs is currently only available rice (Oryza sativa). We report here the molecular functional characterization of two CRY genes, TaCRY1a TaCRY2, from wheat (Triticum aestivum). The expression was most abundant in seedling leaves barely detected roots germinating embryos under normal conditions. TaCRY2 equivalent to that much higher than counterpart. Transition dark...
The cuticle plays important roles in plant development, growth and defense against biotic abiotic attacks. Crystallized epicuticular wax, the outermost layer of cuticle, is visible as white-bluish glaucousness. In crops like barley wheat, glaucousness trait adaption to dry hot cultivation conditions, hentriacontane-14,16-dione (β-diketone) its hydroxy derivatives are major unique components cuticular wax upper parts adult plants. But their biosynthetic pathway physiological role largely...
Abstract Ultraviolet B ( UVB ) irradiation is one of the most dangerous insults for skin and causes sunburn, erythema, photoaging photocarcinogenesis. Curcumin (diferuloylmethane), a yellow spice derived from dried rhizomes Curcuma longa , has been shown to possess significant anti‐inflammatory, antioxidant, anticarcinogenic, antimutagenic, anticoagulant anti‐infective effects. However, protective effects curcumin against acute photo‐damage are poorly understood. In this study, we...
Free and bound phenolic fractions from six buckwheat varieties were investigated for their compositions, antioxidant activities, inhibitory effects on α-glucosidase. The results showed that different have significant differences in phenolic/flavonoid contents, these contents found higher quantities free form than form. HPLC revealed rutin, quercetin, kaempferol-3-O-rutinoside the most abundant components forms, whereas dihydromyricetin was only phenolics activities of DPPH, ABTS·+, OH●, FRAP...
Slow-digesting starch with bioactive functionality has been attracting much interest the increasing incidence of type-2 diabetes and other diet-related illnesses. The present study demonstrates a simple method for preparing inclusion complex reduced enzymic digestion enhanced antioxidant activities using debranched pea (PS) 10-gingerol (10G). Enzymically complexed more 10G formed structurally ordered starch-10G complexes compared to PS that had not debranched. Debranching 6 h resulted in...
Ultraviolet B (UVB) irradiation is the initial etiological factor for various skin disorders, including erythema, sunburn, photoaging, and photocarcinogenesis. Pterostilbene (Pter) displayed remarkable antioxidant, anti-inflammatory, anticarcinogenic activities. This study aimed to investigate effective mechanism of Pter against UVB-induced photodamage in immortalized human keratinocytes.Human keratinocytes were pretreated with (5 10 μM) 24 h prior UVB (300 mJ/cm2). Harvested cells analyzed...
Abstract Previous studies have revealed that dysregulation of long non-coding RNAs (lncRNAs) can facilitate carcinogenesis. This study aims to investigate the biological role a certain lncRNA in cutaneous squamous cell carcinoma (CSCC). According data TCGA database, high expression intergenic non-protein coding RNA 1048 (LINC01048) is an unfavorable prognostic factor for patients with CSCC. Therefore, we further detected pattern LINC01048 CSCC tissues. Obviously, was expressed higher tissues...
Curcumin suppressed ultraviolet (UV) induced skin carcinogenesis and activated the nuclear factor erythroid 2-related 2 (Nrf2) pathway. However, whether curcumin protects injury caused by UV is still unknown. A vitro model was established effects on Hacat cells were detected. Nrf2 knocked down in to verify role protective effect of curcumin. Results indicated that (UVA) (or B (UVB)) irradiation would lead decreased cell proliferation, increased apoptosis, catalase, heme oxygenase 1,...
Lycium barbarum polysaccharide (LBP) is considered an antioxidant agent. NF-E2-related factor-2 (Nrf2) important regulator for protection against UV damage. In this study, we verified the performance of LBP and correlation between Nrf2. HSF cells were treated with to determine dose time dependencies. An response element (ARE) reporter was designed monitor activity Nrf2 pathway. For cells, optimal treatment 300 μg/ml 3 h. The ARE-reporter assay showed that could increase robustness p-Nrf2....
Chromosomal rearrangements (CRs) play important roles in karyotype diversity and speciation. While many CR breakpoints have been characterized at the sequence level yeast, insects, primates, little is known about structure of evolutionary plant genomes, which are much more dynamic genome size organization. Here, we report identification a translocation between chromosome arms 4L 5L Triticeae, fixed several species, including diploid wheat rye, by comparative mapping analysis draft survey...
Since the introduction of CO2 fractional laser in dermatology, multiple clinical evidences have shown its effectiveness treating alopecia areata(AA). However, extent efficacy remains under-researched, with a lack extensive and large-scale comparisons, which is topic global discussion. We present case 13-year-old male child AA. After taking '10 mg oral prednisone acetate' three times daily, applying' compound Siyadan ointment' twice receiving treatment different parameters on area once month....
Starch-phenol complexes are of interest due to their potential for health-related functional properties in addition resistance enzymic digestion. However, the preparation such remains a challenge structural features and low solubility phenols. The present study sets out novel protocol prepare amylose (AM)-polyphenol by forming an AM-lipid complex that incorporates polyphenol. Three polyphenols (resveratrol, curcumin, quercetin), which themselves do not form with AM, were successfully...
Background Ultraviolet B (UVB) radiation is a major environmental factor contributing to skin damage via DNA damage, oxidative stress, inflammation, and collagen degradation. It penetrates the epidermis, disrupts integrity, generates reactive oxygen species (ROS), activating pro-inflammatory pathways such as NF-κB AP-1, inducing matrix metalloproteinases (MMPs). These processes lead structural changes, pigmentation disorders like melasma. Cumulative from UVB also drives photocarcinogenesis,...