A5102909268- Liver Disease Diagnosis and Treatment
- Metabolomics and Mass Spectrometry Studies
- Diabetes Treatment and Management
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Metabolism, Diabetes, and Cancer
- Lipid metabolism and disorders
- Cancer-related molecular mechanisms research
- Endoplasmic Reticulum Stress and Disease
- Thyroid Cancer Diagnosis and Treatment
- Galectins and Cancer Biology
- Peroxisome Proliferator-Activated Receptors
- Obstructive Sleep Apnea Research
- Bariatric Surgery and Outcomes
- Electrolyte and hormonal disorders
- Dialysis and Renal Disease Management
- Muscle metabolism and nutrition
- Pancreatitis Pathology and Treatment
- Parathyroid Disorders and Treatments
- Folate and B Vitamins Research
- Cardiovascular Function and Risk Factors
- Ion Transport and Channel Regulation
- Diabetes Management and Research
- Diet, Metabolism, and Disease
- Chronic Kidney Disease and Diabetes
- Alcohol Consumption and Health Effects
Xuzhou Medical College
2011-2025
Second People’s Hospital of Huai’an
2011-2023
Objective This study aimed to investigate the association of serum betatrophin with status and progression nonalcoholic fatty liver disease (NAFLD). Methods A total 249 subjects who received ultrasonic examination fat content (LFC) were recruited. Anthropometric biochemical examinations performed. Serum was measured by ELISA. Results Compared control group, significantly increased in NAFLD group (P < 0.05). There significant difference among control, low (LLFC), high (HLFC) groups 0.01)....
Association between metabolic syndrome (MS) and mildly reduced estimated glomerular filtration rates (eGFRs) remains unclear. Therefore, we aimed to evaluate the association MS a eGFR in Chinese adults. Anthropometric biochemical examinations were performed 2992 individuals. The was calculated from creatinine level. defined according Adult Treatment Panel III criteria as presence of three or more risk factors. Mildly value 60 90 mL/min/1.73 m2. Multiple linear regression multiple logistic...
This study was to analyse the prevalence of type 2 diabetes mellitus (T2DM) in premenopausal and postmenopausal women.A total 3227 women met requirements from June December 2014, including 207 cases 3020 women. The T2DM associated risk factors two groups were analysed.The with 12.1%, while 19.4% (P < 0.05). Total serum protein (TP) (OR = 1.164 95% CI 1.023-1.324) 0.021) is a major factor for T2DM. increased increase TP. In groups, age 1.037 1.024-1.051) 0.001), BMI 1.076 1.044-1.109) blood...
This study aimed to investigate the effects of PPM1K rs1440581 and rs7678928 single nucleotide polymorphisms (SNPs) on serum branched-chain amino acids (BCAAs) levels cardiovascular disease (CVD) risk.Anthropometric biochemical examinations were performed at baseline end 4 years in 234 individuals who randomly recruited from Diabetes Prevention Programme Huai'an received lifestyle intervention follow up for years. Serum BCAAs (leucine, isoleucine valine (Val)) measured by hydrophilic...
To examine whether elevated glycosylated hemoglobin A1c (HbA1c) is associated with hyperfiltration in a middle-aged and elderly Chinese population. Anthropometric biochemical examinations were performed 2491 individuals from the general population, aged 40–79 years, who participated Huaian Diabetes Prevention Program. The estimated glomerular filtration rate (eGFR) was calculated creatinine levels using CKD-EPI formula. Hyperfiltration defined as eGFR >90th percentile. After adjustment [for...
This study aimed to explore the association of obstructive sleep apnea-hypopnea syndrome (OSAHS) hypoxia indicators with early renal injury and serum fibroblast growth factor 21 (FGF21) in obese type 2 diabetic patients. A total 109 patients diabetes mellitus (T2DM) were recruited, including 70 males 39 females, an average age 52.77 ± 13.57 years BMI 29.08 4.36 kg/m2. Overnight monitoring was performed a portable monitor record respiratory parameters [apnea-hypopnea index (AHI), oxygen...
Previous studies have shown that the elevated levels of circulating branched-chain amino acids (BCAAs) are associated with development insulin resistance and its complications, including obesity, type 2 diabetes, cardiovascular disease some cancers. However, animal models can mimic metabolic state chronically BCAAs in humans rare. Therefore, aim this study was to establish above model analyse changes high BCAA levels. Sixteen 8-week-old Sprague-Dawley (SD) rats were randomly divided into two...
: Intrathyroidal injection using an insulin pen filled with a mixture of lidocaine and triamcinolone acetonide is therapy for subacute thyroiditis (SAT) reported by us previously. We aimed to evaluate the clinical efficacy ultrasound-guided intrathyroidal in treatment SAT.A total 93 patients SAT completed study. All were evaluated via history examination followed thyroid function tests ultrasonography thyroid. After injection, up respect frequency, duration, patient satisfaction. The visual...