- Liver Disease and Transplantation
- Venous Thromboembolism Diagnosis and Management
- Central Venous Catheters and Hemodialysis
- Parathyroid Disorders and Treatments
- Immune Cell Function and Interaction
- Liver Disease Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Bone health and treatments
- Dialysis and Renal Disease Management
- Adenosine and Purinergic Signaling
- Organ Transplantation Techniques and Outcomes
- Vitamin D Research Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Folate and B Vitamins Research
- MicroRNA in disease regulation
- Cancer Immunotherapy and Biomarkers
- Neurological Complications and Syndromes
- Acute Kidney Injury Research
- Vascular Procedures and Complications
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Intracranial Aneurysms: Treatment and Complications
- Airway Management and Intubation Techniques
- Gastrointestinal Tumor Research and Treatment
- Cancer-related molecular mechanisms research
- Diagnosis and Treatment of Venous Diseases
Liaocheng University
2023-2025
Xuzhou Medical College
2014-2024
Jiangsu University
2019-2024
Anhui Provincial Center for Disease Control and Prevention
2024
Soochow University
2024
First Affiliated Hospital of Soochow University
2024
Yangtze University
2013-2023
Lanzhou University Second Hospital
2022-2023
Lanzhou University
2022-2023
Southeast University
2022
Background . Adenosine, derived from the degradation of ATP via ectonucleotidases CD39 and CD73, is a critical immunosuppressive metabolite in hypoxic microenvironment tumor tissue. Adenosine signaling A2aR can inhibit antitumor immune response CD8 + T cells. CD73 high-expressing Tregs play role evasion gastric cancer (GC). The present study investigated underlying mechanism by which suppress responses GC. Materials Methods Fifty-two GC samples were collected, frequency FoxP3 cells density...
Ursodeoxycholic acid (UDCA) can be used as a drug to treat various liver and bile diseases. Currently, the biological synthesis of UDCA is predominantly conducted via two-step enzymatic process in which catalyzed by 7α-hydroxysteroid dehydrogenase (7α-HSDH) 7β-hydroxysteroid (7β-HSDH) succession, utilizing chenodeoxycholic (CDCA) substrate. In this study, an engineered Escherichia coli ( E. ) strain, designated UCA23, was constructed. This strain coexpressed four enzymes under control three...
This study aims to report the Budd-Chiari syndrome clinical research status and progress that has occurred in over nearly 30 years China, emphasize value of imaging facilitating diagnosis based on more than 2500 cases. Findings ultrasonography, computed tomography, magnetic resonance imaging, digital subtraction angiography images are used propose new types subtypes. The subtype classification presented here important for guiding interventional treatment. also proposes a concept anatomical...
To investigate whether serum levels of butyrylcho-linesterase activity, cystatin C, and pre-albumin has the potential value as γ-glutamyl transferase in reflecting gestational diabetes mellitus its fetal outcome.Seventy-six women 76 pregnancies with normal glucose tolerance second trimester were enrolled. Maternal parameters butyrylcholinesterase transferase, detected evaluated. The pregnant complications outcome also evaluated.Levels glycemic variables higher patients than controls. Levels...
Paricalcitol and cinacalcet have been recommended to reduce parathyroid hormone (PTH) levels for patients with secondary hyperparathyroidism (SHPT) chronic kidney disease (CKD), they are able the risk of hypercalcemia hyperphosphatemia. However, date, it has remained uncertain which is better drug. The aim present meta-analysis was evaluate effects on PTH, calcium phosphorus metabolism between two drugs. PubMed, Cochrane Library Embase databases were searched from inception June 1, 2019...