Wenwen Li

ORCID: 0000-0002-1102-1881
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About
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Research Areas
  • Birth, Development, and Health
  • Congenital heart defects research
  • Lipid metabolism and disorders
  • Cholesterol and Lipid Metabolism
  • Atherosclerosis and Cardiovascular Diseases
  • Stress Responses and Cortisol
  • Neuroscience and Neuropharmacology Research
  • Tryptophan and brain disorders
  • Telomeres, Telomerase, and Senescence
  • Cardiac Imaging and Diagnostics
  • Nerve injury and regeneration
  • Coronary Interventions and Diagnostics

Shandong University of Traditional Chinese Medicine
2024

Weatherford College
2023

Guangzhou University of Chinese Medicine
2022

Early life stress is thought to be a risk factor for emotional disorders, particularly depression and anxiety. Although the excitation/inhibition (E/I) imbalance has been implicated in neuropsychiatric whether early affects E/I balance medial prefrontal cortex at various developmental stages unclear. In this study, rats exposed maternal separation (MS) that exhibited well-established paradigm were used evaluate adolescence (postnatal day P43-60) adulthood (P82-100) by behavior tests,...

10.3389/fnins.2021.720286 article EN cc-by Frontiers in Neuroscience 2022-01-04

Atherosclerosis (AS) is the cause of most cardiovascular diseases and imposes a huge economic burden on society. Erchen decoction (ECD) an effective formula for treating AS, but its therapeutic mechanism remains unclear. This study will explore ECD AS using network pharmacology molecular docking.We searched chemical composition information related targets via Traditional Chinese Medicine Systems Pharmacology Database Analysis Platform SwissTargetPrediction databases, gene names correction...

10.1097/md.0000000000035248 article EN cc-by-nc Medicine 2023-11-17

To evaluate the causal relationship between genetically determined telomere length (TL) and atherosclerosis (AS). We performed a 2-sample Mendelian randomization (MR) study to assess potential TL AS (coronary AS, cerebral peripheral (PAD), excluding cerebral, coronary, PAD). The phenotype contained 472,174 participants, 4 subtypes of had 361,194, 218,792, 168,832, 213,140 all European ancestries. single nucleotide polymorphisms (SNPs) strongly associated with atherosclerotic included in this...

10.1097/md.0000000000035875 article EN cc-by-nc Medicine 2023-11-17

Due to the limited self-repair ability of neurons after injury, there has been a lack effective treatments for nerve injury in clinical practice. So, find drugs that promote repair become research hotspot. Schwann cells and play an important role regeneration peripheral nerves injury. This review summarizes classification signaling pathways related as well diseases provides basis further exploration mechanism

10.12206/j.issn.1006-0111.202101027 article EN 药学实践杂志 2021-09-25
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