A5069540243- Diet and metabolism studies
- Nutrition, Genetics, and Disease
- Diet, Metabolism, and Disease
- Fatty Acid Research and Health
- Nutritional Studies and Diet
- Clinical Nutrition and Gastroenterology
- Drug Transport and Resistance Mechanisms
- Hops Chemistry and Applications
- Liver Disease Diagnosis and Treatment
- Genomics, phytochemicals, and oxidative stress
- Child Nutrition and Feeding Issues
- Consumer Attitudes and Food Labeling
- Cholesterol and Lipid Metabolism
- Metabolism and Genetic Disorders
- Phytochemicals and Antioxidant Activities
- Therapeutic Uses of Natural Elements
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Glutathione Transferases and Polymorphisms
- Obesity and Health Practices
- Dietary Effects on Health
- Sulfur Compounds in Biology
- Berberine and alkaloids research
- Cystic Fibrosis Research Advances
- Muscle metabolism and nutrition
- Folate and B Vitamins Research
University of Western States
2015-2024
Institute for Molecular Medicine
2015-2020
American Society for Nutrition
2019
Digital Proteomics (United States)
2007-2010
Psychogenics (United States)
2007-2010
University of Groningen
1997-2002
Amsterdam UMC Location University of Amsterdam
1999
University Medical Center Groningen
1997
Personalized nutrition holds tremendous potential to improve human health. Despite exponential growth, the field has yet be clearly delineated and a consensus definition of term "personalized nutrition" (PN) not been developed. Defining delineating will foster standardization scalability in research, data, training, products, services, clinical practice; assist driving favorable policy. Building on seminal work pioneering thought leaders across disciplines, we propose that personalized...
Public health recommendations for lifestyle modification, including diet and physical activity, have been widely disseminated the prevention treatment of disease. These guidelines are intended overall population without significant consideration individual with respect to one’s genes environment. Personalized medicine is a newly developed term that refers an approach in which individual’s metrics from point-of-care diagnostics used develop medicine-oriented therapeutic strategies improving...
Adverse reactions to foods and adverse drug are inherent in product defects, medication errors, differences individual exposure. Pharmacogenetics is the study of genetic causes variations response pharmacogenomics more broadly involves genome-wide analysis determinants efficacy toxicity. The similarity nutritional genomics stems from innate goal identify variants associated with metabolism disease. Thus, nutrigenomics can be thought as encompassing gene-diet interactions involving diverse...
The working definition of health is often the simple absence diagnosed disease. This common standard limiting given that changes in functional status represent early warning signs impending declines. Longitudinal assessment may foster prevention disease occurrence and modify progression. LIFEHOUSE (Lifestyle Intervention Functional Evaluation-Health Outcomes SurvEy) longitudinal research project explores impact personalized lifestyle medicine approaches on determinants. Utilizing an adaptive...
As the worldwide dietary pattern becomes more westernized, metabolic syndrome is reaching epidemic proportions. Lifestyle modifications including diet and exercise are recommended as first-line intervention for treating syndrome. Previously, we reported that a modified Mediterranean-style, low glycemic load with soy protein phytosterols had favorable impact than American Heart Association Step 1 on cardiovascular disease (CVD) risk factors. Subsequently, screened phytochemicals history of...
Numerous botanicals are purported to improve glucose metabolism and diabetic risk factors with varying degrees of supportive evidence. We investigated 203 commercially available botanical products representing 90 unique species for effects on lipogenic activity in differentiating 3T3-L1 adipocytes. Anti-inflammatory 21 these was further assessed tumor necrosis factor alpha (TNFalpha)-stimulated, mature From results, rho-isoalpha acids, Acacia nilotica bark, fennel, wasabi were tested the...
The lipophilic extracts of the common hops (Humulus lupulus) contain compounds that are readily modified to family isohumulones (e.g., iso-alpha acids). have been found reduce metabolic inflammation and insulin resistance, positively impact dyslipidemia obesity. These effects consistent across studies in multiple cell lines, animal model systems human intervention trials. Mechanistic work has demonstrated these a unique pleiotropic mechanism action which is with their safety range...
In this report, we examine the clinical safety and efficacy of NG440, a phytochemical-based antiinflammatory formula consisting combination rho iso-alpha acids from hops, rosemary, oleanolic acid. previous study, demonstrated that NG440 significantly decreased pain by 50% in patients with osteoarthritis. Consistent these data, results multicentre trial indicate reduced scores joint discomfort, as measured VAS (visual analog scale) methodology. As an ex vivo effects on relief may be due to...
The adequate supply of essential fatty acids (EFA) to the body depends upon sufficient dietary intake and subsequent efficient intestinal absorption.Lipid malabsorption is not only a leading cause EFA deficiency (EFAD), but also occurs secondarily EFAD.Understanding relationship between EFAD lipid may be helpful in development optimization oral treatment strategies.Sequential steps involved absorption, including lipolysis, solubili7ation by bile, uptake into enterocyte, chylomicron secretion...