A5059013718- Muscle metabolism and nutrition
- Exercise and Physiological Responses
- Vitamin D Research Studies
- Receptor Mechanisms and Signaling
- Angiogenesis and VEGF in Cancer
- COVID-19 Clinical Research Studies
- Sepsis Diagnosis and Treatment
- Cardiovascular Function and Risk Factors
- Cerebral Venous Sinus Thrombosis
- Myofascial pain diagnosis and treatment
- Obesity, Physical Activity, Diet
- Long-Term Effects of COVID-19
- Adipose Tissue and Metabolism
- Virus-based gene therapy research
- Lipid metabolism and disorders
- Animal Genetics and Reproduction
- Viral gastroenteritis research and epidemiology
- Cancer, Hypoxia, and Metabolism
- Aortic Disease and Treatment Approaches
- Cardiac Fibrosis and Remodeling
- Prostate Cancer Treatment and Research
- Vitamin C and Antioxidants Research
- Functional Brain Connectivity Studies
- Aortic aneurysm repair treatments
- Inflammatory Biomarkers in Disease Prognosis
General Administration of Sport of China
2023-2025
Southwest Hospital
2018-2024
Army Medical University
2017-2024
Beijing Sport University
2019-2024
Ministry of Science and Technology of the People's Republic of China
2023-2024
Hunan Agricultural University
2024
Qilu Hospital of Shandong University
2019-2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2019-2023
Tibet Autonomous Region People's Hospital
2020-2021
Peking University
1997-2021
Cell survival or death is critical for cardiac function. Myocardial pyroptosis, as a newly recognized programmed cell death, remains poorly understood in sepsis. In this study, we evaluated the effect of aldehyde dehydrogenase (ALDH2) on myocardial pyroptosis and revealed underlying mechanisms We established septic shock mice model by intraperitoneal injection Lipopolysaccharide (LPS, 15 mg/kg) 12 h before sacrifice. It was found that significantly inhibited NOD-like receptor protein 3...
Numerous cognitive and emotional functions are executed asymmetrically between the left right hemispheres. Right hemisphere hyperactivity/left hypoactivity often appears to be a feature in neuroimaging studies of depression. However, few have evaluated abnormalities structural asymmetry untreated patients with major depressive disorder (MDD). In this study, 3-dimensional high-resolution magnetic resonance images were acquired from 35 treatment-naïve MDD (mean age = 28.9 years, 22 females)...
Background Coaches and athletes are increasingly interested in understanding athletes’ serum vitamin D levels, their impact on strength, physical performance, athletic outcomes. Previous meta-analyses were reported with limited sample size no significant overall effect was found. Hence, it is crucial to conduct a thorough up-to-date systematic examination meta-analysis elucidate the potential advantages of supplementing D3 enhancing muscle strength for athletes. Methods We performed...
The aim of this study was to compare the impacts low-molecular-weight (LMW) and high-molecular-weight (HMW) carbohydrate (CHO) sports drinks on rehydration during endurance exercise. Ten middle- long-distance running athletes were selected in a randomized, double-blind, cross-over design. One day before experiment, pre-experiment performed determine VO<inf>2peak</inf>. formal experiment consisted two-stage exercise test. In first test, participants rode an electrically braked cycle ergometer...
Pathological stimulus-triggered differentiation of cardiac fibroblasts plays a major role in the development myocardial fibrosis. Aldehyde dehydrogenase 2 (ALDH2) was reported to exert protective cardiovascular disease, and whether ALDH2 is involved fibroblast remains unclear. In this study, we used transforming growth factor-β1 (TGF-β1) induce human (HCFs) adopted activator Alda-1 verify influence on HCF differentiation. Results showed that activity obviously impaired when treating HCFs...
(1) Background: Probiotics in the form of nutritional supplements are safe and potentially useful for strategic application among endurance athletes. Bifidobacterium animalis lactis BL-99 (BL-99) was isolated from intestines healthy Chinese infants. We combined plasma-targeted metabolomics fecal metagenomics to explore effect 8 weeks supplementation on cross-country skiers' metabolism sports performance. (2) Methods: Sixteen national top-level male skiers were recruited randomly divided into...
Background: Impairments in cognitive and emotional processing are a characteristic of major depressive disorder (MDD), the dorsolateral prefrontal cortex (DLPFC) amygdala involved these processes. However, structural covariance between two areas patients with MDD has not been examined. Whether anatomical patterns further damaged or compensated untreated multiple-episode compared to those first-episode is unclear. Methods: Structural magnetic resonance imaging was performed 35...
Neuropathic pain (NP) is caused by primary injury or dysfunction of the peripheral and central nervous system. Long non-coding RNAs were critical regulators involved in system diseases, however, precise regulatory mechanism remains unclear. This study aims to uncover essential role LINC01119 NP progression further clarify underlying at post-transcriptional level. was significantly upregulated rats spare nerve (SNI) group compared sham group. Functionally, silencing alleviated neuropathic...
To investigate the effects of trigger point dry needling (TrP-DN) on exercise-induced patellofemoral pain syndrome (PFPS).In this randomized, single-blind, parallel-group trial, 50 patients with PFPS were randomly allocated to following two groups: TrP-DN group (n = 25) and Sham 25). Patients in both groups asked perform a stretching exercise quadriceps daily after needling. The received single session points (TrPs) vastus medialis oblique (VMO), lateralis (VL), rectus femoris muscles (once...
Murine models have proved instrumental in studying various aspects of abdominal aortic aneurysm (AAA), from identification underlying pathophysiologic changes to the development novel therapeutic strategies. In current study, we describe a new model which an elastase-treated donor aorta is transplanted recipient mouse and allowed progress aneurysm. We hypothesized that by transplanting one genotype different genotype, can differentiate factors are intrinsic wall those stemming circulation...
Compared to isolated orbital wall fracture, combined floor and medial fractures are more likely be required surgical correction due a higher possibility of complications. However, it remains challenge repair concomitant fracture using one-piece implant the complex anatomic structures orbit. Aiming reduce difficulties enhance therapeutic effects, we repaired unilateral two separated modified titanium mesh plates in this study.A retrospective study was conducted on 21 consecutive patients who...
To evaluate the ablation ranges and temperature rising rates of three microwave antenna with different diameters in vitro bovine vivo porcine livers.In study, ablations (MWA) were induced at a power output 70 W for 5, 8, 10 min; total 54 36 performed, respectively. Temperature measurements performed W/10 min group 3 antennas.In long axis diameter 16G was longer than 15G (P < 0.05) 14G antennae 0.05). The sphericity index higher 0.05 both). In short- long-axis diameters, not statistically...
Masked image modeling (MIM) has become a prevalent pre-training setup for vision foundation models and attains promising performance. Despite its success, existing MIM methods discard the decoder network during downstream applications, resulting in inconsistent representations between fine-tuning can hamper task In this paper, we propose new architecture, RevColV2, which tackles issue by keeping entire autoencoder architecture both fine-tuning. The main body of RevColV2 contains bottom-up...
Objective: Athletes are suffering from many uncertainties and hope to achieve the best possible position under current circumstances of this global coronavirus disease (COVID-19) pandemic. In study, we aimed address severity psychological support for athletes with COVID-19. Methods: We extracted public data news reports up-to-date first seven cases elite COVID-19 confirmed in China made recommendations based on scientific evidence. Results: The mortality who tested positive mild extremely...