Santiago Madero

ORCID: 0000-0002-1123-4211
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About
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Research Areas
  • Bipolar Disorder and Treatment
  • Schizophrenia research and treatment
  • Tryptophan and brain disorders
  • Neuroscience and Neuropharmacology Research
  • Receptor Mechanisms and Signaling
  • Mental Health Research Topics
  • Functional Brain Connectivity Studies
  • Electroconvulsive Therapy Studies
  • Treatment of Major Depression
  • Child and Adolescent Psychosocial and Emotional Development
  • Pharmacological Effects and Toxicity Studies
  • COVID-19 and Mental Health
  • Glioma Diagnosis and Treatment
  • Maternal Mental Health During Pregnancy and Postpartum
  • Psychosomatic Disorders and Their Treatments
  • Long-Term Effects of COVID-19
  • Cannabis and Cannabinoid Research
  • Digital Mental Health Interventions
  • Advanced MRI Techniques and Applications
  • Diet and metabolism studies
  • Reproductive Physiology in Livestock
  • Psychedelics and Drug Studies
  • Obsessive-Compulsive Spectrum Disorders
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Cell death mechanisms and regulation

Universitat de Barcelona
2020-2025

Hospital Clínic de Barcelona
2019-2025

Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2020-2025

Centro de Investigación Biomédica en Red de Salud Mental
2021-2025

Hospital Universitario Río Hortega
2024

Instituto de Salud Carlos III
2022-2024

Neuroscience Institute
2020

Fundación Santa Fe de Bogotá
2013

Universidad de Oviedo
2001

Hospital Universitario Severo Ochoa
2001

Abstract Background and Hypothesis A pro-inflammatory phenotype has been related to psychotic disorders. The neutrophil-lymphocyte ratio (NLR) is an accessible biomarker that could be helpful characterize this systemic inflammation state. Study Design This study evaluated the NLR in a cohort of 310 subjects with first episode psychosis (FEP) matched group 215 healthy controls, recruited 16 Spanish centers participating PEPs Project. We investigated measures over 2 years prospective,...

10.1093/schbul/sbac089 article EN Schizophrenia Bulletin 2022-07-25

Depressive and manic episodes within bipolar disorder (BD) major depressive (MDD) involve altered mood, sleep, activity, alongside physiological alterations wearables can capture. Firstly, we explored whether wearable data could predict (aim 1) the severity of an acute affective episode at intra-individual level 2) polarity euthymia among different individuals. Secondarily, which were related to prior predictions, generalization across patients, associations between symptoms data. We...

10.2196/45405 article EN cc-by JMIR mhealth and uhealth 2023-03-20

Is there a difference in live birth rates following endometrial preparation with either constant or increasing estrogen dose fresh embryo transfer from oocyte donation cycles?There is no between versus an of after cycles oral transdermal supplementation.Endometrial (EP) and progesterone, embryo-endometrial synchronicity are determinant for adequate implantation. Estrogen crucial different exogenous administration patterns could imply variations on EP. Moreover, undergoes metabolization by...

10.1093/humrep/dew099 article EN Human Reproduction 2016-05-01

What is the quality of life (QoL) and mental health infertile heterosexual couples from different nations (Italy, Germany France) undergoing cross-border oocyte donation (OD) in Spain?Women have lower QoL more anxiety than their male partners; overall French Italian German counterparts.In Europe, thousands move across national borders annually to seek ARTs, primarily OD, driven mainly by legal restrictions countries origin. Most research shows that infertility ARTs affect patients' QoL. The...

10.1093/humrep/dex247 article EN Human Reproduction 2017-06-30

10.1016/j.euroneuro.2023.02.002 article EN European Neuropsychopharmacology 2023-02-15

Abstract Background Clozapine is the recommended treatment for managing treatment-resistant schizophrenia (TRS), and immunological mechanisms may be involved in its unique antipsychotic efficacy. This study investigated whether baseline immune abnormalities measured with blood cell count ratios can predict clinical response after initiating clozapine patients naïve TRS. Methods A longitudinal design was developed, involving 32 diagnosed treatment-resistant, clozapine-naïve...

10.1055/a-2290-6386 article EN Pharmacopsychiatry 2024-04-15

We report a 80-year-old woman who suffered from primary progressive aphasia for 3 years. Cranial CT and MRI studies showed moderate cerebral atrophy, more marked in the left frontal temporal lobes, SPECT brain scans revealed hypometabolism lobes. Neuropathologic examination of lobe biopsy demonstrated Gallyas-positive intracytoplasmic inclusions looking like fibrillary tangles cell processes, probably glial cells. Glial were immunolabelled with antibodies to ubiquitin phosphorylion-dependent...

10.1159/000007961 article EN European Neurology 1998-01-01

This study was aimed at identifying differences in the prodromal symptoms and their duration, risk factors markers of vulnerability patients presenting a first episode mania (FEM) or psychosis (FEP) with onset late adolescence adulthood order to guide tailored treatment strategies.Patients FEM FEP underwent clinical assessment. Prodromes were evaluated Bipolar Prodrome Symptom Scale-Retrospective (BPSS-R). Chi-squared tests conducted assess specific symptoms, between groups. Significant...

10.1111/acps.13415 article EN Acta Psychiatrica Scandinavica 2022-02-16

Obstetric complications (OCs) may contribute to the heterogeneity that characterizes psychiatric illness, particularly phenotypic presentation of first episode psychoses (FEP). Our aim was examine relationship between OCs and socio-demographic, clinical, functioning neuropsychological characteristics in affective non-affective FEP. We performed a cross-sectional,study where we recruited participants with FEP 2011 2021, retrospectively assessed using Lewis-Murray scale. were used as...

10.1016/j.jpsychires.2022.05.005 article EN cc-by Journal of Psychiatric Research 2022-05-17

The DiGeorge anomaly (DGA) is occasionally associated with cellular immunodeficiency. We report a female infant diagnosed complete DGA, who developed fatal, high grade, non-Hodgkin's lymphoma that expressed Epstein-Barr virus (EBV). Non-Hodgkin's should be considered in children DGA.

10.1136/adc.81.5.444 article EN Archives of Disease in Childhood 1999-11-01
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