A5101905432- Energy Harvesting in Wireless Networks
- Genetics, Aging, and Longevity in Model Organisms
- Protist diversity and phylogeny
- Microtubule and mitosis dynamics
- Ultrasound and Cavitation Phenomena
- Cavitation Phenomena in Pumps
- Innovative Energy Harvesting Technologies
- Genetic and Kidney Cyst Diseases
- Cellular Mechanics and Interactions
- Analytical Chemistry and Sensors
- Conducting polymers and applications
- Wireless Power Transfer Systems
- Erythrocyte Function and Pathophysiology
- Advanced Sensor and Energy Harvesting Materials
- Advanced Battery Technologies Research
- Rocket and propulsion systems research
- Electrochemical Analysis and Applications
- Aerosol Filtration and Electrostatic Precipitation
- Spaceflight effects on biology
- Genetic Neurodegenerative Diseases
- Neuroscience and Neural Engineering
- Ubiquitin and proteasome pathways
- Organic Electronics and Photovoltaics
- Cyclone Separators and Fluid Dynamics
- Analog and Mixed-Signal Circuit Design
Tsinghua University
2017-2024
Center for Life Sciences
2017-2024
Significance We find that the coronin family protein POD-1 debranches actin network in vitro. Our results reveal regulates organization and cell polarity migrating neuroblasts one-cell−stage embryos of C. elegans . provide evidence F-actin debranching is critical for establishing during migration asymmetric division.
This article proposed the first fully integrated synchronous electric-charge extraction (SECE) interface, featuring: 1) no external passive components and smallest normalized on-chip capacitance; 2) an increased energy-extraction efficiency; 3) a maximized extracted power regardless of input output conditions. With multi-step soft-charging (MSC) technique relaxing conduction loss, we can effectively minimize capacitance while improving efficiency. To further depress control positive current...
Dynamic properties are essential for microtubule (MT) physiology. Current techniques in vivo imaging of MTs present intrinsic limitations elucidating the isotype-specific nuances tubulins, which contribute to their versatile functions. Harnessing power AlphaFold2 pipeline, we engineered a strategy minimally invasive fluorescence labeling endogenous tubulin isotypes or those harboring missense mutations. We demonstrated that specifically designed 16-amino acid linker, coupled with sfGFP11...
Cavitation is a common phenomenon in hydraulic power industry, ship propulsion, pump station and other industrial fields. In the present work, high-speed camera used to visualize flow field rotational hydrodynamic cavitation reactor (RHCR) closed cycle test rig, numerical simulation carried out based on RNG k-ε turbulence model Zwart-Gerber-Belamri (ZGB) model. Influence of hole diameter, height cone bottom length performance RHCR are comprehensively investigated. The results show that good...
Perturbation of spectrin-based membrane mechanics causes hereditary elliptocytosis and spinocerebellar ataxia, but the underlying cellular basis pathogenesis remains unclear. Here, we introduced conserved disease-associated spectrin mutations into Caenorhabditis elegans genome studied contribution to neuronal migration dendrite formation in developing larvae. The loss resulted ectopic actin polymerization outside existing front secondary protrusions, leading defective positioning morphology...
This work proposes the first ultrasonic PEH interface capable of operating up to 340kHz over a wide temperature range. As shown in Fig. 1, major contributions include: 1) proposed auto-calibration technique using <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$\mathrm{t}_{\text{flip}}/2$</tex> detection and adaptive closed-loop timing calibration (ACTC) achieve high accuracy low power consumption; 2) charge recycling (CR) bootstrap driver with...
This paper proposed design of a low power potentiostat for electrochemical biosensing with high input dynamic range. A current compensation circuit is to extend the detection Chopper stabilization used suppress low-frequency noise, realizing accuracy. The was fabricated in 0.18-$\mu$m CMOS process occupying silicon area 0.43 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . experimental results show range 68 dB consumption 105 $\mu$W.
Wireless power transfer (WPT) has emerged as a vital technology for biomedical implants and wearable devices, which eliminates the need physical connectors associated risks of infections, tissue damage, device failure. A highly efficient receiver is essential to suppress temperature rising during charging well improve rate [1]. However, voltage receiving coil varies dramatically based on requirements, loadings, transmission distance, axes misalignment [2]. Furthermore, maximum point tracking...
Abstract The RNG k-ε turbulence model and mass transport cavitation are applied to simulate the cavitating flows in a rotational hydrodynamic generator with rotor stator. is designed have surface dimples on rotor. analyses focused mainly accuracy reliability of calculation method demonstrated by good agreement between experimental numerical results. pressure distribution, streamline distribution vapor volume fraction five different structures (5 diameter d=11mm, 13mm, 15mm, 17mm, 19mm) under...
Abstract Kinesin-2 motors power the anterograde intraflagellar transport (IFT), a highly ordered process that assembles and maintains cilia. It remains elusive how kinesin-2 are regulated in vivo . Here we perform forward genetic screen to isolate suppressors rescue ciliary defects constitutive active mutation of OSM-3-kinesin (G444E) C. elegans sensory neurons. We identify DYF-5 DYF-18, which encode homologs mammalian male germ cell-associated kinase (MAK) cell cycle-related (CCRK). Using...
Abstract Perturbation of spectrin-based membrane mechanics causes hereditary elliptocytosis and spinocerebellar ataxia, but the underlying cellular basis pathogenesis remains unclear. Here, we introduced conserved disease-associated spectrin mutations into C. elegans genome studied contribution to neuronal migration dendrite formation in developing larvae. The loss generates an ectopic actin polymerization outside existing front secondary protrusions, leading defective positioning morphology...
Abstract The current investigation is aimed to simulate the internal flows in a rotational cavitation generator with rotor and stator by using RNG k-ε turbulence model Zwart-Gerber-Belamri model. design of that provided surface dimples. A detailed analysis pressure distribution, vapor volume fraction distribution velocity five different structures (5 depth dimples h =25mm, 35mm, 45mm, 55mm, 65mm) under same operation condition, presented. simulation results demonstrate characteristics area...