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Research Areas
- Gut microbiota and health
- Infant Nutrition and Health
- Neonatal Respiratory Health Research
University of Cincinnati Medical Center
2022
Cincinnati Children's Hospital Medical Center
2022
Although modern clinical practices such as cesarean sections and perinatal antibiotics have improved infant survival, treatment with broad-spectrum alters intestinal microbiota causes dysbiosis. Infants exposed to an increased likelihood of life-threatening infections, including pneumonia. Here, we investigated how the gut sculpt pulmonary immune responses, promoting recovery resolution infection in newborn rhesus macaques. Early-life antibiotic exposure interrupted maturation commensal...
10.1126/scitranslmed.abl3981
article
EN
Science Translational Medicine
2022-06-15
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