A5047780178- Asymmetric Synthesis and Catalysis
- Asymmetric Hydrogenation and Catalysis
- Catalysis and Oxidation Reactions
- Catalytic Processes in Materials Science
- Catalytic C–H Functionalization Methods
- Axial and Atropisomeric Chirality Synthesis
- Cyclopropane Reaction Mechanisms
- Chemical Reaction Mechanisms
- Molecular spectroscopy and chirality
- Fungal Biology and Applications
- Oxidative Organic Chemistry Reactions
- Catalytic Alkyne Reactions
- Phytochemistry and Bioactivity Studies
- Phytochemistry and Biological Activities
- Cancer therapeutics and mechanisms
- Natural product bioactivities and synthesis
- Catalytic Cross-Coupling Reactions
- Genomics, phytochemicals, and oxidative stress
- biodegradable polymer synthesis and properties
- Advanced Battery Materials and Technologies
- Natural Antidiabetic Agents Studies
- Synthesis and Catalytic Reactions
- Chemical Synthesis and Analysis
- Parkinson's Disease Mechanisms and Treatments
- Synthesis and pharmacology of benzodiazepine derivatives
Dalian University
2022-2025
Dalian University of Technology
2022-2025
Northeast Normal University
2017-2024
Nanjing University of Finance and Economics
2023
National University of Singapore
2021
University of Michigan
2020
Shenyang Pharmaceutical University
2016-2018
Metal-catalyzed allenylic substitution reactions where allenes serve as electrophilic precursors have been recognized a rapid way for novel allene construction. On the contrary, chemistry in which act nucleophiles has far less investigated, especially powerful platform such metal-catalyzed allylic alkylation reactions. We herein describe two unprecedented palladium-catalyzed of an nucleophile. In first reaction, using vinyloxazolidinones allyl precursor, asymmetric allylation trisubstituted...
Immersive authoring is an increasingly popular technique to design AR/VR scenes because and testing can be done concurrently. Most existing systems, however, are single-user limited either AR or VR, thus constrained in the interaction techniques. We present XRDirector, a role-based collaborative immersive system that enables designers freely express interactions using VR devices as puppets manipulate virtual objects 3D physical space. In we adapt roles known from filmmaking structure process...
A novel copper-catalyzed [3 + 2] cycloaddition reaction of alkynes with nitrile oxides generated in situ from the coupling copper carbene and nitroso radical has been developed. The three-component provides a simple efficient method for construction isoxazoles highly regioselective manner single step. On basis experimental results density functional theory calculations, catalytic cycle (CuI–CuII–Cu0–CuI) this cascade cyclization is proposed.
B═O multiple bonds are fundamentally important owing to the unique property of B and its potential as a tool in catalysis. Herein by means DFT calculations, we investigated situ generation transient -B═O species nonmetallic inorganic boron oxides demonstrated superior ability capture alkoxyl radicals under conditions oxidative dehydrogenation propane (ODHP). Boron-containing materials emerging promising catalysts for ODHP, while an extensive understanding underlying mechanisms remains...
Regulating the diastereoselectivity of a reaction is highly attractive but extremely challenging, density functional theory computations are employed to investigate an iridium-catalyzed ligand-controlled switch propargylic C−H functionalization. Energetically most...
// Ya Gao 2, * , Lihan Zhu 1, Jing Guo 2 Ting Yuan 1 Liqing Wang Hua Li and Lixia Chen Wuya College of Innovation, School Traditional Chinese Materia Medica, Key Laboratory Structure-Based Drug Design & Discovery, Ministry Education, Shenyang Pharmaceutical University, 110016, People's Republic China Hubei Natural Medicinal Chemistry Resource Evaluation, Pharmacy, Tongji Medical College, Huazhong University Science Technology, Wuhan 430030, These authors have contributed equally to this work...
Boron-based oxidative dehydrogenation of propane (ODHP) is emerging as a promising protocol because its efficient conversion to propene, while the correlation between structures boron-containing materials and their catalytic activity remains unclear. In this work, by means density functional theory calculations, mechanism ODHP on surface boron phosphate (BPO4) was studied. Three types sites, tri- (>B-OH, 3coord-B) tetra- (≡BOH, 4coord-B) coordinated oxygenated sites site (≡POH, 4coord-P),...
A phthalide glycoside, (3R, 4R)-4-O-β-D-glucopyranosyl-senkyunolide (1), and a megastigmane (6S, 7R)-3-oxo-megastigma-4, 8-dien-7-O-β-D-glucoside (2), along with two known aglycones (3-4), were isolated from the 70% EtOH extract of fresh whole grass Apium graveolens L. Their structures elucidated by extensive spectroscopic analysis. All these compounds tested for their inhibitory effects on nitric oxide (NO) production in RAW 264.7 macrophages. Among them, 3 4 showed potent activity against...
Palladium-catalyzed regio- and stereoselective allylic alkylation of 5-vinyloxazolidine-2,4-diones with azlactones worked well to give the Z configuration various trisubstituted amino acid derivatives.
Metal-free boron-containing materials are growing to be promising choices in oxidative dehydrogenation (ODH) of light alkanes alkenes, while it remains unclear how the boron content and second element that constitutes scaffold accommodate B may influence their catalytic activity. Herein, by means density functional theory study nanosized carbide, we studied mechanisms ODH propane (ODHP) catalyzed three types carbides, B13C2, B4C, h-BC, which differ from each other contents chemical...
DFT calculations disclosed the chemoselectivity of rhodium carbenoid and water co-catalyzed O–H C–H insertion reactions with three 1,3-diketone substrates.
Chiral phosphoric acid (CPA)-catalyzed enantioselective arylation reactions have attracted immense attention recently. However, the preferential activation model in stereodetermining step is controversial, and hence, origin of enantioselectivity still far from being understood. Two stereochemical models are provided on basis asymmetric arylations iminoquinones with naphthylamines (reaction 1) or naphthols 2) catalyzed by (R/S)-TRIP to explain high effect CPAs scaffolds. Unexpectedly, our...
DFT calculations disclosed that the sign of enantioselectivity in chiral-phosphoric-acid catalyzed reactions can be tuned by BINOL- or SPINOL-derived backbones.