A5100747490- Steroid Chemistry and Biochemistry
- Plant biochemistry and biosynthesis
- Neurological Disease Mechanisms and Treatments
- Pharmacogenetics and Drug Metabolism
- Genomics, phytochemicals, and oxidative stress
- Natural product bioactivities and synthesis
- Phytochemical compounds biological activities
- HIV Research and Treatment
- Pharmacological Effects of Medicinal Plants
- Neurological Disorders and Treatments
- Inflammation biomarkers and pathways
- Glutathione Transferases and Polymorphisms
- Oral and Craniofacial Lesions
- Ocular Surface and Contact Lens
- Chemotherapy-induced organ toxicity mitigation
- Medicinal Plant Pharmacodynamics Research
- Carcinogens and Genotoxicity Assessment
- Clostridium difficile and Clostridium perfringens research
- Traditional Chinese Medicine Analysis
- Clinical practice guidelines implementation
- Viral Infectious Diseases and Gene Expression in Insects
- Molecular Biology Techniques and Applications
- Pediatric Urology and Nephrology Studies
- Insect Resistance and Genetics
- Cancer survivorship and care
China Medical University
2021
Hebei Agricultural University
2021
East China University of Science and Technology
2019-2021
Czech Academy of Sciences, Institute of Biotechnology
2021
Shenyang Pharmaceutical University
2017-2019
State Council of the People's Republic of China
2019
Chongqing Dazu District People's Hospital
2015
First People's Hospital of Yunnan Province
2015
Innovation Team (China)
2015
Shanxi Medical University
2015
As an accurate and convenient technique, the qRT-PCR is always used in quantitative expression analysis of functional genes. Normalization data relies on stable reference The fall armyworm Spodoptera frugiperda (J. E. Smith) important invasive migratory pest that seriously threatens corn production around world. In this paper, we selected 10 candidate genes (18S, AK, RPL10, RPS24, 28S, SOD, ATP, GAPDH, ACT, a-TUB) determined their levels under different conditions (different developmental...
The Xanthoceras sorbifolia Bunge husks were known for their abundant triterpenoids resource, which contributed to many bioactivities, such as antitumor, antiinflammatory and neuroprotection. present study has led the purification of a new triterpenoid saponin, 21β-O-acetyl-xanthohuskiside A (1), together with six barrigenol derivatives (2–7), whose structures authenticated on basis NMR, HR-MS, IR spectrum acid hydrolysis experiment. Compound 7 showed more noteworthy cytotoxicity towards...
We identified an inhibitory intermediate, 4-ene-3-keto steroids, that limits the bioconversion rate and provided a solution based on resin adsorption for improving 9α-OH-AD production efficiency in commercial-scale process.
Barrigenol-like triterpenoids (BATs) showed promising anti-tumor, anti-inflammatory and anti-Alzheimer's activities, while, the inhibitory strength was usually affected by their states with aglycones or glycosides. In order to find more BATs as new anti-tumor agents much efficiency, chemical pharmaceutical studies were carried out on acid hydrolysate product (AHP) of Semen Aesculi crude extract. Thirteen BATs, including three (1-3), two glycosides (4, 5) eight known (6-13) obtained. Compound...