A5100384286- Wheat and Barley Genetics and Pathology
- Plant Disease Resistance and Genetics
- Genetic Mapping and Diversity in Plants and Animals
- Genetics and Plant Breeding
- Chromosomal and Genetic Variations
- Identification and Quantification in Food
- Plant Pathogens and Resistance
- Genetic diversity and population structure
- Mycotoxins in Agriculture and Food
- Plant Molecular Biology Research
- Plant pathogens and resistance mechanisms
- Cancer-related molecular mechanisms research
- Plant-Microbe Interactions and Immunity
- Crop Yield and Soil Fertility
- Plant Stress Responses and Tolerance
- Fish Biology and Ecology Studies
- Genomics and Phylogenetic Studies
- Legume Nitrogen Fixing Symbiosis
- Plant nutrient uptake and metabolism
- Soil erosion and sediment transport
- Food Quality and Safety Studies
- Soybean genetics and cultivation
- Photosynthetic Processes and Mechanisms
- MicroRNA in disease regulation
- Soil Carbon and Nitrogen Dynamics
Nanjing Agricultural University
2010-2025
Chongqing University of Education
2024-2025
Peking University First Hospital
2020-2025
Peking University
2020-2025
State Key Laboratory of Chemical Engineering
2025
East China University of Science and Technology
2022-2025
Shandong Academy of Agricultural Sciences
2014-2024
Blood Center of Zhejiang Province
2024
China Geological Survey
2024
China University of Geosciences (Beijing)
2012-2024
Significance Nanotechnology-based drug delivery is expected to bring new hope for cancer treatment by enhancing anticancer efficacy, overcoming resistance, and reducing toxicity. In this respect, we developed an innovative system based on a self-assembling amphiphilic dendrimer, which can generate supramolecular nanomicelles with large void space in their core encapsulate drugs high loading capacity. The resulting drug-encapsulated effectively enhance potency combat resistance promoting...
An amphiphilic dendrimer bearing a hydrophobic alkyl chain and hydrophilic poly(amidoamine) dendrons is able to combine the advantageous features of lipid vectors deliver heat shock protein 27 siRNA produce potent gene silencing anticancer activity in vitro vivo prostate cancer model (see picture). This can be used alternatively for treating various diseases.
Previous studies have shown that wheat grain yield is seriously affected by drought stress, and leaf cuticular wax reportedly associated with tolerance. However, most focused on biosynthesis model species. The effects of tolerance rarely been studied. aims the current study were to under stress using above-mentioned NILs discuss possible physiological mechanism high stress. Compared water-irrigated (WI) conditions, content (CWC) in glaucous non-glaucous drought-stress (DS) conditions both...
The microenvironment of lymph node metastasized tumors (LNMT) determines tumor progression and response to therapy, but a systematic study LNMT is lacking. Here, we generate single-cell maps primary (PTs) paired LNMTs in 8 breast cancer patients. We demonstrate that the activation, cytotoxicity, proliferation T cells are suppressed compared with PT. CD4+CXCL13+ more likely differentiate into an exhausted state. Interestingly, LAMP3+ dendritic display lower cell priming activating ability...
Wheat powdery mildew, caused by Blumeria graminis f. sp. tritici (Bgt), is a devastating disease that threatens wheat production worldwide. Pm12, which originated from Aegilops speltoides, wild relative of wheat, confers strong resistance to mildew and therefore has potential use in breeding. Using susceptible mutants induced gamma irradiation, we physically mapped isolated Pm12 showed it be orthologous Pm21 Dasypyrum villosum, also wheat. The function was validated via ethyl...
In this study, the ZmPIS gene with a maize ubiquitin promoter was introduced into (Zea mays L.) inbred line DH4866 by an Agrobacterium‐mediated method to explore function of in response drought stress. The overexpression resulted significantly elevated levels most phospholipids, galactolipids leaves compared those WT and markedly up‐regulated expression some genes involved phospholipids metabolism pathway ABA biosynthesis after Consistent these results, stress tolerance sense transgenic...
Drought has become one of the most serious abiotic stresses influencing crop production worldwide. Understanding molecular regulatory networks underlying drought adaption and tolerance in crops is great importance for future breeding. microRNAs (miRNAs), as important components post-transcriptional regulation, play crucial roles response adaptation plants. Here, we report a miRNome analysis two maize inbred lines with contrasting levels under soil field. Differential expression showed 11 34...
With the aim of developing dendrimer nanovectors with a precisely controlled architecture and flexible structure for DNA transfection, we designed PAMAM dendrimers bearing triethanolamine (TEA) core, branching units pointing away from center to create void spaces, reduce steric congestion, increase water accessibility benefit delivery. These are shown form stable nanoparticles DNA, promote cell uptake mainly via macropinocytosis, act as effective transfection in vitro on epithelial...
Drought is a major threat to maize growth and production. Understanding the molecular regulation network of drought tolerance in great importance. In this study, two inbred lines with contrasting were tested field under natural soil well-watered conditions. addition, transcriptomes their leaves was analyzed by RNA-Seq. total, 555 2,558 genes detected specifically respond tolerant sensitive line, respectively, more positive tendency genotype. Furthermore, 4,700, 4,748, 4,403 4,288 showed...
Food safety is a global public health issue, which often arises from asymmetric information between consumers and suppliers. With the development of technology in human life, building food traceability sharing platform viewed as one best ways to overcome trust crisis resolve problem asymmetry China. However, among myriad available supply chain, there lack knowledge on consumer preference. Based best-worst scaling approach, this paper investigated preferences for vegetable, pork, dairy...
In plants, the mechanism for ecological sympatric speciation (SS) is little known. Here, after ruling out possibility of secondary contact, we show that wild emmer wheat, at microclimatically divergent microsite "Evolution Canyon" (EC), Mt. Carmel, Israel, underwent triple SS. Initially, it split following a bottleneck an ancestral population, and further diversified to three isolated populations driven by disruptive selection. Remarkably, two postzygotically (SFS1 SFS2) sympatrically...
Peanut yield and quality face significant threats due to climate change soil degradation. The potential of biochar technology address this challenge remains unanswered, though is acknowledged for its capacity enhance the microbial community plant nitrogen (N) supply. A field study was conducted in 2021 on oil peanuts grown a sand-loamy Primisol that received organic amendments at 20 Mg ha
Plant-parasitic nematodes are one of the major threats to crop protection. However, only limited nematicides currently available and confronted with a growing resistance problem, which necessitates development novel nematicides. In this study, series trifluorobutene amide derivatives was synthesized through strategy bond reversal, their nematicidal activity against Meloidogyne incognita evaluated. The bioassay showed that compounds C2, C10, C18 some analogues thereof exhibited good activity....