Despite recent advances in the treatment of human colon cancer, chemotherapy efficacy against cancer is still unsatisfactory. In present study, effects concomitant inhibition epidermal growth factor receptor (EGFR) and DNA methyltransferase were examined cells. We demonstrated that decitabine (a inhibitor) synergized with gefitinib (an EGFR to reduce cell viability colony formation SW1116 LOVO However, combination two compounds displayed minimal toxicity NCM460 cells, a normal mucosal...

PurposeThis study aimed to evaluate the effect of delayed lactogenesis Ⅱ on early milk volume in mothers expressing for their preterm infants.Methods142 with infants participated a longitudinal cohort study, volumes over 14 days postpartum between (≥ 72 hours) and non-delayed Ⅱ(< were compared using Wilcoxon's rank sum tests.ResultsThe prevalence lactogenesisⅡ among was 36.0% (36/100). There existed negative correlations onset daily volumes( rs = −0.525∼−0.354, p .002 ∼ < .001). The every...

It has been demonstrated that microRNA‑192 (miR‑192) serves important roles in different cancer types, including breast cancer, prostate and colorectal cancer. However, its biological role function remains largely unknown. The present study aimed to determine the of miR‑192 In study, one normal two tumor cells lines were used, which included mammary fibroblast cell line Hs578Bst, a more aggressive MDA‑MB‑231 less MCF‑7. effect on proliferation was detected with an MTT assay. Western blot...

Over 90 percent of Deaf and Hard Hearing (DHH) children in the United States are born to hearing parents, who have little no command American Sign Language (ASL). This leaves majority DHH at risk language deprivation early childhood. study investigates design space Augmented Reality (AR) wearable technologies supporting parents offer sign environments for young children. We conducted an online survey with 65 participants (hearing/DHH teachers aged 6 months 5 years) gather preferences...

Abstract The aim of this respective study was to assess the graft signal/noise quotient (SNQ) value and associated factors based on magnetic resonance imaging (MRI) after lateral meniscal allograft transplantation (LMAT). Patients with LMAT were included. SNQ, width anterior horn (WAH), midbody (WMB), posterior (WPH) each meniscus, coronal extrusion (CGE), cartilage meniscus distance (ACMD) (PCMD) measured using MRI tested by multivariate stepwise regression analysis. relative percentage...

Objective To analyze and explore the correlation between onset time of lactogenesis Ⅱ lactation yield early stage after delivery in preterm's mothers by continuously determining hospitalized Ⅱin neonatal intensive care unit (NICU) . Methods We measured recorded from 100 premature labour puerpera with hospital Obstetrics Department at a class Ⅲ grade A general Shandong Province. The relative factors delayed (DOL Ⅱ) were investigated lactation-related comprehensive questionnaire...

BACKGROUND:Breast feeding can enhance preterm infants' neurodevelopmental outcome, regulate immune function development. This study aims to develop breastfeeding evaluation indicators system in neonatal intensive care units (NICU) and provide theoretical basis for all-round of breast quality hospitalized infants. MATERIAL AND METHODS:This was performed based on Avedis Donabedian's theory medical quality. Preterm infant frame initially formed by using literature review, clinical on-spot...

Objective To establish the rating scale of breast feeding and determinate effect feeding.Methods Using clinical survey,experts' consultation,literature review,theoretical study pre-survey methods to develop content scale;190 pairs mothers babies were surveyed by this data for reliability validity was analyzed.Results The Cronbach α coefficient is 0.82 Spearman rank rs 0.901 5.The structure analysis show that logical stable in specialty.Using evaluate breastfeeding effectiveness discharged...

To report the first case series of robotic single-site (RSS) surgery via da Vinci Si Surgical System for mature cyst teratoma cystectomy in China.The study was devised as a retrospective single medical center. Five patients with teratomas requested minimally invasive surgical treatment. These were treated RSS between January 2014 and 2015. cystectomies performed platform Hainan branch PLA General Hospital. Data regarding patient characteristics, approach, perioperative clinical outcomes...

Objective To systemically compare the effect of 3% hypertonic saline (HS) and mannitol in reducing intracranial hypertension. Methods Cochrane Library, PubMed, Embase, China Biological Medicine Database, CNKI, Wanfang VIP were retrieved. The related literature about randomized controlled trials comparing hypertension with from establishment databases to January 2016 was collected. RevMan 5.3 software used conduct Meta-analyze for each indicator. Results Finally, 15 articles met...

Objective To explore the coordination of a day in operating room on surgery arrangement,reduce average hospital and costs improve utilization rate rooms,and peed up operation turnover effect.Methods Retrospective analysis November 2009 to December 2010 our were implemented,and 480 cases LC/DS same period 476 regular routine LC patients clinical data collected.Time hospital,cost patient satisfaction compared between two groups.A surgical was arranged according types,characteristics operative...

Objective To assess the prevalence and related factors of postpartum depression in mothers preterm infants neonatal intensive care unit (NICU). Methods A total 83 who met inclusion exclusion criteria were investigated by using Edinburgh Postnatal Depression Scale (EPDS) comprehensive questionnaire for NICU, analysis was performed on SPSS 13.0 Spearman correlation Logistic regression analysis. Results Among mothers, 38 got EPDS score 10 above, which accounted 45.78% (38/83). The...

Objective To discuss the safety management of operative position Da Vinci robot assisted gynecologic surgery, and make sure operation is performed smoothly. Methods To summarize 46 cases abdomen, pelvic surgery from Feb. 2014 to Dec. 2015 , gynecologicaloperation in lithotomy analyze related nursing factors, establish guidelines management. Results 46 gynecological were carried out by successfully, no complications reported following up procedure. Conclusions With correct...

Objective To investigate safety managements of surgical instruments employed for the minimally invasive surgery through link management so as to guarantee safety. Methods All procedure were performed, such distribution after sterilization, use,takeover 1 910 cases from July December 2009 in our hospital. involved included thoracoscopes, laparoscope, uteroscope, ventriculoscope and robots. We organized training medical staff, filed out procedures,enhanced their consciousness management,...