A5014860951- Meningioma and schwannoma management
- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Head and Neck Surgical Oncology
- Neurofibromatosis and Schwannoma Cases
- Spinal Fractures and Fixation Techniques
- Neurosurgical Procedures and Complications
- Cerebrospinal fluid and hydrocephalus
- Cerebrovascular and Carotid Artery Diseases
- Intracerebral and Subarachnoid Hemorrhage Research
- Spinal Dysraphism and Malformations
- Advanced Neuroimaging Techniques and Applications
- Pituitary Gland Disorders and Treatments
- Peripheral Nerve Disorders
- Anatomy and Medical Technology
- Acute Ischemic Stroke Management
- Spinal Cord Injury Research
- Bone Tumor Diagnosis and Treatments
- Craniofacial Disorders and Treatments
- Moyamoya disease diagnosis and treatment
- Spine and Intervertebral Disc Pathology
- Facial Trauma and Fracture Management
- Trigeminal Neuralgia and Treatments
University of Pavia
2018-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2018-2025
Policlinico San Matteo Fondazione
2018-2025
Azienda Ospedaliero Universitaria di Sassari
2025
University of Sassari
2025
Yeditepe University
2025
ASST Fatebenefratelli Sacco
2024
IRCCS Humanitas Research Hospital
2022
Humanitas University
2022
University of Campania "Luigi Vanvitelli"
2022
BACKGROUND AND OBJECTIVES: The middle fossa approaches are tremendously versatile for treating small vestibular schwannomas, selected petroclival meningiomas, midbasilar trunk aneurysms, and lesions of the petrous bone. Our aim was to localize internal acoustic canal safely drill apex with these approaches. This study demonstrates a new method locate during surgery in fossa. METHODS: microsurgical anatomy floor studied 11 formalin-fixed silicone-injected cadaveric heads. Extradural...
Abstract Surgeons frequently approach the foramen ovale (FO) via infratemporal fossa (ITF) to treat trigeminal neuralgia. However, this percutaneous procedure could be unsuccessful due anatomical factors. The present study aimed assess FO morphology and its relationship with lateral pterygoid process plate (LPPP), emphasizing coexisting ITF variants. One-hundred-and-eight (216 sides) adult dried skulls were evaluated at (FO LPPP). maximum anteroposterior lateromedial distances (APD LMD)...
OBJECTIVE This study aimed to evaluate the impact of augmented reality intraoperative fiber tractography (AR-iFT) on extent resection (EOR), motor functional outcome, and survival patients with primary area (M1) intra-axial malignant tumors. METHODS Data obtained from who underwent AR-iFT for M1 tumors were retrospectively analyzed compared those a control group unaugmented (unAR-iFT). A full asleep procedure electrical stimulation mapping fluorescein guidance was performed in both groups....
Background and Objectives: Trauma coagulopathy begins at the moment of trauma. This study investigated whether upon arrival in emergency room (ER) is correlated with increased hemotransfusion requirement, more hemodynamic instability, severe anatomical damage, a greater need for hospitalization, hospitalization intensive care unit (ICU). We also analyzed trauma unfavorable indices, such as acidemia, lactate increase, base excess (BE) increase. Material Methods: conducted prospective,...
Circulating platelets (PLTs) are able to affect glioblastoma (GBM) microenvironment by supplying oncopromoter and pro-angiogenic factors. Among these mediators, sphingosine-1-phophate (S1P) has emerged as a potent bioactive lipid enhancing cell proliferation survival. Here, we investigated the effect of “tumor education”, characterizing PLTs from GBM patients in terms activation state, protein content, potential. healthy donors (HD-PLTs) (GBM-PLTs) were collected, activated, analyzed flow...
Background and objectives: Anticoagulants are thought to increase the risks of traumatic intracranial injury poor clinical outcomes after blunt head trauma. The safety using direct oral anticoagulants (DOACs) compared vitamin K antagonists (VKAs) hemorrhage (ICH) is unclear. This study aims compare incidence post-traumatic ICH following mild (MHI) assess need for surgery, mortality rates, emergency department (ED) revisit volume ICH. Materials Methods: a retrospective, single-center...
Background: The main objectives of this paper are to outline the essential tools, instruments, and equipment needed set up a functional microsurgery laboratory that is affordable for low-income hospitals identify cost-effective alternatives acquiring microsurgical equipment, such as refurbished or donated collaborating with medical device manufacturers discounted rates, exploring local suppliers. Methods: Step-by-step instructions were provided on setting laboratory, including...
Aberrant nitric oxide synthase 2 (NOS2) expression has been suggested as an interesting therapeutic target that is being implicated a component of the molecular profile several human malignant tumors, including glioblastoma, which most aggressive brain tumor with limited options and poor prognosis. The aim present work was to evaluate effect 1400W, specific NOS2 inhibitor, on glioma cells in terms clonogenic potential, proliferation, migration rate, neurosphere generation ability. determined...
OBJECTIVE The theoretical advantages of augmented reality (AR) with diffusion tensor imaging (DTI)–based high-definition fiber tractography (HDFT) and sodium fluorescein (F) in high-grade glioma (HGG) surgery have not been investigated detail. In this study, the authors aimed to evaluate safety efficacy profiles HDFT-F microscope-based AR cytoreductive for newly diagnosed supratentorial HGGs. METHODS Data patients HGGs who underwent using technique were reviewed compared those a cohort...
Major trauma is the leading cause of mortality in world patients younger than 40 years. However, proportion elderly people who suffer has increased significantly. The purpose this study to assess correlation old age with and other unfavorable outcomes. We assessed on one hand, anatomical criteria such as ISS values number body regions affected, hemodynamic instability criteria, various shock indices, Glasgow Coma Scale. Finally, we also evaluated biochemical parameters, lactate, BE, pH...
The relevance of nitric oxide synthase 2 (NOS2) as a prognostic factor in Glioblastoma Multiforme (GBM) malignancy is emerging. We analyzed the effect NOS2 inhibitor 1400W on autophagic flux and extracellular vesicle (EV) secretion U87MG glioma cells. effects stem cells (GSC)-derived EVs adherent were evaluated. Cell proliferation migration examined while using Counting Kit-8 assay (CCK-8) scratch wound healing assay. cycle profile apoptosis by flow cytometry. Autophagy-associated acidic...