A5033427217- Bone Tissue Engineering Materials
- Calcium Carbonate Crystallization and Inhibition
- Soil and Unsaturated Flow
- biodegradable polymer synthesis and properties
- Clay minerals and soil interactions
- Bone health and osteoporosis research
- Orthopaedic implants and arthroplasty
- Grouting, Rheology, and Soil Mechanics
- Polymer Nanocomposites and Properties
- Paleontology and Stratigraphy of Fossils
- Force Microscopy Techniques and Applications
- Hydrocarbon exploration and reservoir analysis
- 3D Printing in Biomedical Research
- Cellular Mechanics and Interactions
- Collagen: Extraction and Characterization
- Bone health and treatments
- Electrospun Nanofibers in Biomedical Applications
- Cancer Cells and Metastasis
- Polymer Surface Interaction Studies
- NMR spectroscopy and applications
- Enzyme Structure and Function
- Ferroelectric and Piezoelectric Materials
- Polymer crystallization and properties
- Semiconductor materials and devices
- Nanoparticle-Based Drug Delivery
North Dakota State University
2016-2025
Dakota State University
2007-2025
ORCID
2022
Case Western Reserve University
2016
Cornell University
2016
University of Leeds
2016
Google (United States)
2010
University of Southern Mississippi
2000-2003
University of Washington
1994-2002
University of California, Davis
1992
Recently, biopolymer-based nanocomposites have been replacing synthetic polymer composites for various biomedical applications. This is often because of the biocompatible and biodegradable behavior natural polymers. Several studies reported pertaining to synthesis characterization chitosan(chi)/montmorillonite(MMT) chitosan (chi)/hydroxyapatite (HAP) tissue engineering In present work, a novel nanocomposite chitosan/montmorillonite (MMT)/hydroxyapatite was developed The composite prepared...
Increasing traffic volumes, heavier loads, higher tire pressures, and performance problems with asphalt concrete mixtures under adverse conditions are leading state highway departments to using modified binders enhance the physical properties of mix. This paper reports advantages nanoclays (NC) as modifiers. Dynamic mechanical analysis, flexural creep stiffness, tests were conducted on NC-asphalt nanocomposite. In addition, Fourier transform infrared (FTIR) testing was evaluate nature...
Significant differences in biochemical parameters between normal and tumor tissues offer an opportunity to chemically design drug carriers which respond these changes deliver the drugs at desired site. For example, overexpression of matrix metalloproteinase-9 (MMP-9) enzyme extracellular can act as a trigger modulate delivery from carriers. In this study, we have synthesized MMP-9-cleavable, collagen mimetic lipopeptide forms nanosized vesicles with POPC, POPE-SS-PEG,...
Scaffolds based on chitosan/polygalacturonic acid (ChiPgA) complex containing montmorillonite (MMT) clay modified with 5-aminovaleric were prepared using freeze-drying technique. The MMT was introduced to improve mechanical properties of the scaffold. microstructure scaffolds influenced by incorporation nanoclays. MTT assay also indicated that number osteoblast cells in ChiPgA comparable hydroxyapatite known for its osteoconductive properties. Overall, composite found be biocompatible. This...
Nanoclay modified with unnatural amino acid was used to design a nanoclay-hydroxyapatite (HAP) hybrid by mineralizing HAP in the nanoclay galleries mimicking biomineralization. This (in situ HAPclay) fabricate polycaprolactone (PCL)/in HAPclay films and scaffolds for bone regeneration. Cell culture assays imaging were study interactions between human mesenchymal stem cells (hMSCs) PCL/in composites (films scaffolds). SEM indicated MSC attachment, formation of mineralized extracellular (ECM)...
In this work, novel modified nanoclays were used to mineralize hydroxyapatite (HAP) mimicking biomineralization in bone. This situ HAPclay was further incorporated into chitosan/polygalacturonic acid (Chi/PgA) scaffolds and films for bone tissue engineering. Differences microstructure of the observed depending on changes processing with ChiPgA biopolymer system. Response human mesenchymal stem cells (hMSCs) these studied using imaging assays. SEM micrographs indicate that hMSCs able adhere...
The mechanical response of the interlayer hydrated montmorillonite was evaluated using steered molecular dynamics. An atomic model sodium previously constructed. In current study, with multiple layers water. Using dynamics, external forces were applied to individual atoms clay surface, and studied. displacement versus stress strain relationships various parts paper describes construction model, simulation procedure, results simulations. Some previous work are further interpreted in light...
The organic phase of nacre, which is composed primarily proteins, has an extremely high elastic modulus as compared to that bulk and also undergoes large deformation before failure. One reason for this unusually could be the mineral−organic interactions. In work, we elucidate specific role mineral proximity on structural response proteins in biological composites such nacre through molecular modeling. "glycine-serine" domain a protein Lustrin A been used model system. It found amount work...