A5044301110- Veterinary Medicine and Surgery
- Antibiotics Pharmacokinetics and Efficacy
- Urinary Tract Infections Management
- Veterinary Oncology Research
- Pediatric Urology and Nephrology Studies
- Bacterial Identification and Susceptibility Testing
- Virus-based gene therapy research
- Urological Disorders and Treatments
- Herpesvirus Infections and Treatments
- Neuroblastoma Research and Treatments
- Veterinary Pharmacology and Anesthesia
- Pancreatic and Hepatic Oncology Research
- Antibiotic Use and Resistance
- Pancreatitis Pathology and Treatment
- Vitamin C and Antioxidants Research
- Antibiotic Resistance in Bacteria
- Hematopoietic Stem Cell Transplantation
- Urinary Bladder and Prostate Research
- Escherichia coli research studies
- Liver Disease and Transplantation
- Amoebic Infections and Treatments
- Cancer, Lipids, and Metabolism
- Anesthesia and Pain Management
- Veterinary Orthopedics and Neurology
- Vitamin K Research Studies
University of Wisconsin–Madison
2014-2024
University of Wisconsin System
2020
Veterinary Medical Teaching Hospital
2014
To determine the prevalence of subclinical bacteriuria and its natural clinical course over a 3-month period in healthy female dogs.Observational, prospective, cross-sectional study.101 client-owned dogs.In all dogs, screening clinicopathologic tests bacteriologic culture urine were performed. In culture-positive was confirmed by 2 positive results within weeks dogs reevaluated at 3 months.The 9 101 (8.9%). Three-month follow-up data available for 8 with bacteriuria. Four had persistent...
Awareness of prescribing practices helps identify opportunities to improve antibiotic use (AU).
Long-duration beta-lactam antibiotics are used for empirical treatment in female dogs with uncomplicated bacterial cystitis. However, women cystitis treated short-duration potentiated sulfonamides because longer courses of beta-lactams result lower cure and higher recurrence rates.Short-duration sulfonamide is more efficacious than long-duration achieving clinical microbiological cures cystitis.Thirty-eight client-owned dogs.Randomized, double-blinded, placebo-controlled trial. Dogs were...
Oxidative stress plays a role in the pathogenesis of many systemic diseases. Hospitalized human patients are glutathione, cysteine, and ascorbate deficient, antioxidant depletion has been correlated with poor clinical outcome. To date little is known about concentrations hospitalized veterinary patients. The purpose this study was to determine whether ascorbate, or glutathione present ill dogs cats compared healthy controls.Clinically would be depleted, correlate illness severity...
The clinical use of cyclosporine is described in a group client-owned cats diagnosed with idiopathic pure red cell aplasia (PRCA). All 10 were treated combinations glucocorticoids and cyclosporine. Of the cats, eight for which follow-up data was available achieved maintained remission median 31 406 days, respectively. Therapy reduced or discontinued 7/8 cats; 2/7 off therapy 5/7 relapsed. Remission reinduced four 3/4 long-term on low dose therapy. Adverse effects associated responsive to...
Background Antioxidant depletion and lipid peroxidation have been correlated with disease severity associated poor outcomes. Hypothesis/Objectives Supplementing dogs N ‐acetylcysteine ( NAC ) during the first 48 hours of hospitalization will increase cysteine, normalize glutathione concentrations, decrease degree illness. Animals Sixty systemically ill hospitalized client‐owned 14 healthy control dogs. Methods Randomized investigator‐blinded, placebo‐controlled prospective study. Dogs were...
Previous reports of true pancreatic cysts in cats have suggested that are benign incidental findings. This case report describes the progressive clinical course and diagnostic findings a cat with multiple recurrent cysts. The presenting signs included diarrhea, intermittent vomiting, polyphagia, marked weight loss. Pancreatic were identified via abdominal ultrasound computed tomography (CT). An exploratory celiotomy lesion histopathology confirmed unknown etiology. One month after surgery...
Hyperthyroidism, the most common endocrine disorder in cats, has been associated with low serum cobalamin concentrations. Whether this is a functional deficiency of clinical importance not assessed.Cats hyperthyroidism experience which correlates their catabolic state and reversible return euthyroid state.Thirty-nine client-owned hyperthyroid cats.Prospective observational study. Serum cobalamin, methylmalonic acid, scores were determined each cat at enrollment when (60 days after...
Background Oxidative stress is associated with a diverse group of liver disorders across species. Objectives Determine whether glutathione (GSH) concentration in plasma and red blood cells correlates GSH dogs evaluate other markers systemic oxidative stress, vitamin E urine 8‐isoprostanes/creatinine (F 2 ‐IsoPs/Cr) concentrations, correlate GSH. Animals Thirty‐four client‐owned undergoing clinically indicated biopsy 15 healthy control dogs. Methods Prospective, observational cross‐sectional...
Objectives The purpose of this study was to describe the clinical use nitrofurantoin in client‐owned dogs with lower urinary tract infections. primary aim patient population, dosage, treatment duration, outcome and side effects. Materials Methods Medical records an institution were retrospectively reviewed from July 2013 January 2019. Results Nitrofurantoin prescribed population 14 for Recurrent infection diagnosis all dogs. Each dog's associated a nitrofurantoin‐susceptible,...
Objectives To assess whether combination antioxidant supplementation for 30 days in systemically ill dogs alters status, degree of lipid peroxidation, clinical score and survival. Materials Methods Forty client‐owned systemically‐ill hospitalised were eligible inclusion. Dogs randomised to no (NS; n=19) or with N‐acetylcysteine/S‐adenosylmethionine/silybin vitamin E (AS; n=20) days. Clinical oxidative biomarkers including glutathione, cysteine, E, selenium urine isoprostanes/creatinine (F 2...
"Diagnostic and therapeutic challenges for dogs with urinary tract infections caused by extended-spectrum β-lactamase-producing Escherichia coli" published on 01 Oct 2018 American Veterinary Medical Association.
OBJECTIVE To evaluate the clinical performance of a commercially available compartmentalized urine culture and antimicrobial susceptibility test plate (CCSP) for identification canine bacteriuria assessment isolate susceptibility. DESIGN Cross-sectional study. ANIMALS 71 dogs. PROCEDURES Urine samples (n = 84) were divided into 3 aliquots. One aliquot (reference culture) was plated on medium ≤ 1 hour after collection quantitative testing by standard laboratory methods, another stored at 4°C...
A 6-month-old, male intact, German Shepherd Dog (GSD) was examined for a 3 month history of chronically loose feces since the owner acquired him at 12 weeks age. Over period dog maintained an excellent appetite with little weight gain and had persistently abnormal feces. The consistency ranged from soft to liquid diarrhea. tested positive Giardia spp. on multiple occasions despite treatments fenbendazole metronidazole. Additional therapies including tylosin probiotics resulted in transient...
The study aimed to describe the clinical use of chloramphenicol in client-owned cats, examining patient population, sites infection, targeted pathogens, prescribed dosing regimen, outcomes and adverse effects.
Abstract Background There is a lack of consensus regarding which markers disease resolution to prioritise when assessing treatment response in client‐owned dogs with aspiration‐induced lung injury. This study describes the change over time and agreement between clinical used determine resolution. Methods Physical examination (PE), owner‐reported signs (CS‐O), thoracic radiographs (TXR) scores C‐reactive protein (CRP) concentrations were determined at enrolment, after 24, 48 72 hours, 7, 14...