A5002962035- Atrial Fibrillation Management and Outcomes
- Antimicrobial Peptides and Activities
- Microbial infections and disease research
- Bacteriophages and microbial interactions
- Probiotics and Fermented Foods
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Cardiac Arrhythmias and Treatments
- Aquaculture disease management and microbiota
- Cardiovascular Function and Risk Factors
- Plant Virus Research Studies
- Antibiotic Resistance in Bacteria
- Genomics and Phylogenetic Studies
- Plant nutrient uptake and metabolism
- Cardiac electrophysiology and arrhythmias
- Biochemical and Structural Characterization
- Cardiac pacing and defibrillation studies
- Rice Cultivation and Yield Improvement
- Plant responses to water stress
- Crop Yield and Soil Fertility
- Venous Thromboembolism Diagnosis and Management
- Mycobacterium research and diagnosis
- Cardiomyopathy and Myosin Studies
- Agriculture Sustainability and Environmental Impact
- Irrigation Practices and Water Management
Jilin Agricultural University
2016-2025
China University of Petroleum, Beijing
2025
Anhui Academy of Agricultural Sciences
2019-2024
Renji Hospital
2015-2024
Shanghai Jiao Tong University
2014-2024
Jilin Agricultural Science and Technology University
2023
State Key Laboratory of Oncogene and Related Genes
2018
Shanghai Cancer Institute
2018
London School of Economics and Political Science
2016
Christie's
2015
The emergence of multi-drug-resistant (MDR) pathogens has considerably challenged the development new drugs. Probiotics that inhibit MDR offer advantages over chemical antibiotics and drugs due to their increased safety fewer side effects. This study reported Weissella cibaria P-8 isolated from pickles showed excellent antibacterial activity against intestinal pathogens, particularly Escherichia coli B2 was highest. survival rates W. at pH 2.0 0.3% bile salt concentration were 72% 71.56%,...
Background Left atrial (LA) dysfunction is associated with morbidity and mortality. To the knowledge of authors, relationship LA strain to long-term prognosis in participants ST-segment elevation myocardial infarction (STEMI) unknown. Purpose evaluate as a outcome predictor STEMI prospective, multicenter cardiac MRI cohort. Materials Methods Participants who underwent primary percutaneous coronary intervention from 10 sites (EARLY-MYO-CMR registry, clinical trial number NCT03768453) were...
Abstract The combination effects of nitrogen (N) fertilizer and planting density on maize yield, N use efficiency the characteristics canopy radiation capture are not well documented in Huanghuaihai Plain region China. A 2-year field experiment was conducted from 2017 to 2018 a split plot design with two levels (240 204 kg ha −1 ) applied main plots three plant densities (67,500, 77,625 87,750 plants allocated sub plots. Our results show that 30% greater combined 15% lower rate (basal N)...
Antibiotic tolerance has become an increasingly serious crisis that seriously threatened global public health. However, little is known about the exogenous factors can trigger development of antibiotic tolerance, both in vivo and vitro. Herein, we found addition citric acid, which used many fields, obviously weakened bactericidal activity antibiotics against various bacterial pathogens. This mechanistic study shows acid activated glyoxylate cycle by inhibiting ATP production bacteria,...
Drought stress is the key factor limiting soybean yield potential. Soybean seed formation involves a coordinated “subtending leaf-podshell-seed” process, but little known about assimilation and transport of photoassimilates in subtending leaves, podshells seeds or their relationships with under drought stress. To address these research gaps, two-year experiments two cultivars, Wandou 37 (drought tolerant) Zhonghuang 13 sensitive), were conducted three soil water content (SWC) conditions 2020...
Abstract Background Bacterial infections have become more challenging to treat due the emergence of multidrug-resistant pathogenic bacteria. Combined antibiotics prove be a relatively effective method control such resistant strains. This study aim investigate synergistic activity eugenol combined with colistin against collection clinical isolated Escherichia coli ( E.coli ) strains, and evaluate potential interaction. Methods Antimicrobial susceptibility, minimum inhibitory concentration...
Nonalcoholic fatty liver disease (NAFLD), characterized by hepatic steatosis (HS), insulin resistance (IR), and inflammation, poses a high risk of cardiometabolic disorders. Ubiquitin specific protease 4 (USP4), deubiquitinating enzyme, is pivotally involved in regulating multiple inflammatory pathways; however, the role USP4 NAFLD unknown. Here, we report that expression was dramatically down-regulated livers from patients different mouse models induced high-fat diet (HFD) or genetic...
Abstract Splitting nitrogen (N) application is beneficial for enhancing sweetpotato growth and promoting optimum yields under reduced N rates; however, studies concerning how split can affect dynamics utilization are limited. Field experiments were conducted from 2015 to 2016 determine affects uptake use efficiency (NUE) a rate. Two cultivars (Xushu 22 Shangshu 19) planted four treatments, conventional basal of 100 kg ha −1 (100:0), 80 (80:0), two equal applications (basal 35 days after...
Antimicrobial peptides (AMPs) have a unique action mechanism that can help to solve global problems in antibiotic resistance. However, their low therapeutic index and poor stability seriously hamper development as agents. In order overcome these problems, we designed based on the sequence template XXRXXRRzzRRXXRXX-NH2, where X represents hydrophobic amino acid like Phe (F), Ile (I), Leu (L), while zz Gly-Gly (GG) or d-Pro-Gly (pG). Showing effective antimicrobial activity against...
The poor stability of antibacterial peptide to protease limits its clinical application. Among these limitations, trypsin mainly exists in digestive tract, which is an insurmountable obstacle orally delivered peptides. OM19R a random curly polyproline cationic antimicrobial peptide, has high activity against some gram-negative bacteria, but pancreatin poor. According the structure-activity relationship OM19R, all amino acid residues (l-arginine and l-lysine) at cleavage sites were replaced...
ABSTRACT Tylosin is a commonly used macrolide antibiotic, which utilized in livestock; its release through animal excrement can have detrimental environmental effects. Biodegradation of tylosin (TYL) an effective bioremediation method. In this study, we identified novel and efficient TYL-degrading bacterial strain, Kurthia gibsonii TYL-A1, capable degrading 75 mg/L TYL within 5 days at 30°C, pH 7, with 3% inoculum yeast extract as the nitrogen source. The bacterium degraded 99% days. Both...
Mycoplasma bovis has spread widely throughout the world via animal movement and become an important pathogen of bovine respiratory disease. However, minimum inhibitory concentrations antimicrobials for have not been studied in China. The objective this study was to determine prevalence antibiotic resistance isolated from young cattle with infection detected 32/45 outbreaks at beef farms 8 provinces isolates were susceptible or had medium sensitivity ciprofloxacin, enrofloxacin doxycycline,...
Abstract Aeromonas veronii is an important aquatic zoonotic pathogen in humans and animals. In recent years, extracellular proteins from bacteria have been found to be the major pathogenic factors for The aim of this study was systematically analyze nine sources A. effects hisJ on virulence. We screened only common different by liquid chromatography−tandem mass spectrometry identified gene . then constructed Δ (deleted) C‐ (complemented) variants TH0426 assess biological function While...