A5101810130- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Cardiovascular Function and Risk Factors
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Chronic Kidney Disease and Diabetes
- Coronary Interventions and Diagnostics
- Ultrasound and Hyperthermia Applications
- Cardiac Arrhythmias and Treatments
- Cancer-related molecular mechanisms research
- Photoacoustic and Ultrasonic Imaging
- Liver Disease Diagnosis and Treatment
- Blood Pressure and Hypertension Studies
- Hormonal Regulation and Hypertension
- Cardiac Valve Diseases and Treatments
- Lipoproteins and Cardiovascular Health
- Advanced MRI Techniques and Applications
- Cardiovascular Disease and Adiposity
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular Health and Disease Prevention
- Aortic Disease and Treatment Approaches
- Aortic aneurysm repair treatments
- Circular RNAs in diseases
- Atherosclerosis and Cardiovascular Diseases
- Health Promotion and Cardiovascular Prevention
Southern Medical University
2015-2025
Nanfang Hospital
2013-2025
Sichuan University
2021
West China Hospital of Sichuan University
2021
Guangzhou Regenerative Medicine and Health Guangdong Laboratory
2021
Key Laboratory of Guangdong Province
2021
Shift work is associated with increased risk of acute myocardial infarction (AMI) and worsened prognosis. However, the mechanisms linking shift prognosis in AMI remain unclear. This study sought to investigate impact on reperfusion injury, a major determinant clinical outcomes AMI. Study patient data were obtained from database EARLY-MYO-CMR (Early Assessment Myocardial Tissue Characteristics by CMR STEMI) registry, which was prospective, multicenter registry patients ST-segment elevation...
Objective: To evaluate the prognostic value of systemic immune-inflammatory index (SII) for predicting in-hospital major adverse cardiovascular events (MACEs) in patients with acute myocardial infarction (AMI) and establish a relevant nomogram. Methods: This study included 954 AMI patients. We examined three inflammatory factors (SII, platelet to lymphocyte ratio (PLR) neutrophil (NLR)) see which one predicts MACEs better. The predictors were subsequently screened using bidirectional...
Background Left atrial (LA) dysfunction is associated with morbidity and mortality. To the knowledge of authors, relationship LA strain to long-term prognosis in participants ST-segment elevation myocardial infarction (STEMI) unknown. Purpose evaluate as a outcome predictor STEMI prospective, multicenter cardiac MRI cohort. Materials Methods Participants who underwent primary percutaneous coronary intervention from 10 sites (EARLY-MYO-CMR registry, clinical trial number NCT03768453) were...
Thrombotic events cannot be completely prevented by antithrombotics, implicating a therapeutic gap due to inflammation, not yet sufficiently addressed mechanism. Neutrophil extracellular traps (NETs) are an essential interface between inflammation and thrombosis, but exactly how the NETotic process is initiated maintained during arterial thrombosis remains incompletely understood.We found that plasma concentrations of C5a were higher in patients with ST-elevation myocardial infarction...
Severe degenerative mitral regurgitation (DMR) can cause a poor prognosis if left untreated. For patients considered at prohibitive surgical risk, transcatheter edge-to-edge repair (TEER) has become an accepted alternative therapy. The DragonFly valve system is innovative evolution of the TEER device family to treat DMR.
Triglyceride-glucose (TyG) index is a simple marker of insulin resistance. However, insufficient data available on whether the TyG associated with worsening renal function (WRF) in elderly. Therefore, this study was designed to explore association between and WRF based community elderly cohort.In study, 7,822 (aged ≥ 65 years) adults from southern China were enrolled divided into four groups according quartiles. The primary endpoint incident chronic kidney disease (CKD), defined as estimated...
Visceral adiposity index (VAI) and lipid accumulation product (LAP) are comprehensive indicators to evaluate visceral fat determine the metabolic health of individuals. Carotenoids a group naturally occurring antioxidants associated with several diseases. The purpose this investigation was explore association between serum carotenoid concentration VAI or LAP.The data were obtained from National Health Nutrition Examination Survey 2001 2006. levels carotenoids evaluated using high-performance...
The long non-coding RNA (lncRNA) PTENP1 is a pseudogene of phosphatase and tensin homologue deleted on chromosome ten (PTEN), has been implicated in smooth muscle cell (SMC) proliferation apoptosis. the PTEN. However, it unclear whether how functions apoptosis human aortic SMCs (HASMCs). Here, we hypothesised that inhibits HASMC enhances by promoting PTEN expression. PCR analysis Western blot assays respectively showed both were up-regulated dissection (AD) samples. overexpression...
ABSTRACT This study aimed to investigate the associations between 24‐hour urinary cortisol levels (24 h‐UFC) and alterations in left ventricular (LV) structure function patients with essential hypertension. A prospective cohort was conducted, including 315 hypertension who underwent baseline 24 h‐UFC measurement echocardiographic evaluation of mass (LVM), ejection fraction (LVEF), E/e′ ratio. Over a mean follow‐up period 28.54 ± 14.21 months, were grouped into tertiles based on levels....
Pulmonary vein isolation (PVI) using conventional power (30–35 W) radiofrequency ablation (RFA) has been an effective treatment strategy for paroxysmal atrial fibrillation (PAF), but its longer duration may cause collateral damage to peripheral tissue including esophageal and phrenic nerve. High-power (HP) RFA, due better transmural performance shorter duration, reduce the adjacent is expected be a safe efficient strategy. In this retrospective cohort study, we included 259 patients with PAF...
Abstract Atherosclerotic cardiovascular disease is considered as the leading cause of mortality and morbidity worldwide. Accumulating evidence supports an important role for long noncoding RNA (lnc ) in pathogenesis atherosclerosis. Nevertheless, lnc atherosclerosis‐associated vascular dysfunction underlying mechanism remain elusive. Here, using microarray analysis, we identified a novel RP 11‐714G18.1 with significant reduced expression human advanced atherosclerotic plaque tissues. We...
Visceral adiposity index (VAI) is an indicator of visceral fat accumulation and dysfunction. However, little known about whether VAI associated with worsening renal function (WRF) in the elderly. Therefore, our study aimed to explore association between WRF among elderly population. In total, 5,583 participants (aged ≥ 65 years) who participated annual health checkups at least twice January 2017 July 2021 were enrolled divided into four groups according quartiles. The primary endpoint was...
Background: Previous studies have established blood pressure (BP) as a pivotal factor influencing no-reflow following primary percutaneous coronary intervention (PCI) in patients with ST-elevation acute infarction (STEMI). However, no relevant study has been conducted to investigate the optimal range of BP associated lowest risk among STEMI so far. Therefore, our objective was evaluate association between pre-PCI and occurrence STEMI. Method: We included 1025 undergoing PCI. The categorized...