A5100341822- Acute Kidney Injury Research
- Chronic Kidney Disease and Diabetes
- Cardiac Arrest and Resuscitation
- Cardiac Imaging and Diagnostics
- Acute Ischemic Stroke Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Acute Myocardial Infarction Research
- Heart Failure Treatment and Management
- Liver Disease Diagnosis and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Coronary Interventions and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Parathyroid Disorders and Treatments
- Computational Drug Discovery Methods
- SARS-CoV-2 and COVID-19 Research
- Thermal Regulation in Medicine
- Cardiovascular Function and Risk Factors
- Atherosclerosis and Cardiovascular Diseases
- Cardiac Health and Mental Health
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Sepsis Diagnosis and Treatment
- Adipokines, Inflammation, and Metabolic Diseases
- Renal and Vascular Pathologies
- Medication Adherence and Compliance
- Carcinogens and Genotoxicity Assessment
Sichuan University
2017-2025
West China Hospital of Sichuan University
2017-2025
Sun Yat-sen Memorial Hospital
2025
Sun Yat-sen University
2025
Southern Medical University
2014-2024
Nanfang Hospital
2021-2024
China Medical University
2024
Jinan University
2024
Zhujiang Hospital
2014-2024
Southern University of Science and Technology
2024
Triglyceride-glucose (TyG) index is a simple marker of insulin resistance. However, insufficient data available on whether the TyG associated with worsening renal function (WRF) in elderly. Therefore, this study was designed to explore association between and WRF based community elderly cohort.In study, 7,822 (aged ≥ 65 years) adults from southern China were enrolled divided into four groups according quartiles. The primary endpoint incident chronic kidney disease (CKD), defined as estimated...
The Klotho protein is a well-documented anti-aging known for its diverse biological functions. Hyperlipidemia an established independent risk factor various chronic diseases. However, there limited understanding of the connection between and hyperlipidemia. aim was to assess association serum levels hyperlipidemia among adults.
Infectious diseases can sometimes lead to pandemics, often transmitted through public and social gatherings, including in-person hospital visits. Consequently, there is an urgent need for innovative approaches prevent their spread. Taking COVID-19 as example, we have explored a remote, contactless online model that offers the medical consultations, professional psychological counseling, chronic disease management thereby mitigating risk of new transmissions resulting from This was...
Contrast media (CM) is widely used in cardiac catheterization; however, it may cause contrast-induced acute kidney injury (CI-AKI) which severely increases mortality. MicroRNA (miRNA) has been found to participate the process of (AKI), and this discovery great potential for diagnosis treatment. However, role miRNA CI-AKI still unclear. This study aimed investigate regulatory effect miRNAs exert CI-AKI.We established a novel, representative, isotonic model by using CM iodixanol, commonly...
Although serum uric acid (UA) was regarded to be involved in cardiovascular disease, the role of UA (SUA) as a risk factor acute myocardial infarction (AMI) is controversial. We investigated whether hyperuricemia linked with long-term mortality patients AMI who underwent percutaneous coronary intervention (PCI).Patients received PCI were consecutively included. The definition preprocedural SUA level >7 mg/dL (417 mmol/L) males and >6 (357 females. All-cause assessed during 2.3-year median...
The contents of selenomethionine (SeMet) and selenomethylcysteine (SeMC) in Selenium-Enriched black garlic extract (Se-BGE), a popular functional food Asian countries, were 2.9 ± 0.6 μg/g 12.2 2.3 by PITC pre-column derivatization UPLC-MS method. Improved histological injury, significant extension the median survival time, attenuated serum levels alanine aminotransferase, total bilirubin SOD activity observed acute liver failure (ALF) rats treated with Se-BGE (1.0 g/mL). 1HNMR-based...
Abstract Chemodynamic therapy (CDT) has garnered significant attention for treating diverse malignant tumours due to its minimally invasive nature, reduced damage healthy tissues, and potential mitigation of side effects. However, application in glioblastoma (GBM) is hindered by the diminished capacity CDT agents traverse blood–brain barrier (BBB), inadequate tumour targeting efficiency, restricted availability H 2 O within microenvironment (TME). To address these challenges, we devised a...
Objectives To establish a nomogram for contrast-induced acute kidney injury (CI-AKI) risk assessment among patients with chronic disease (CKD) undergoing coronary angiography (CAG) or percutaneous intervention (PCI). Design Prospective observational cohort study. Setting Southern China. Interventions None. Participants 643 consecutive CKD (defined as estimated glomerular filtration rate calculated by Modification of Diet in Renal Disease formula <60 mL/min/1.73 mm 2 ) were enrolled....
Abstract Background Digital health tools (WeChat or mobile apps) provide opportunities for new methods of hypertension management hypertensive patients. However, the willingness these patients to use social media and apps remains unclear. This study explored characteristics requirements willing digital (WDH) manage hypertension. Methods From February March 2018, we administered questionnaires 1089 with at eight Chinese primary medical units. We assessed independent risk factors WDH...
Abstract The ischaemia-reperfusion (I/R) model is a widely used of acute kidney injury (AKI) and renal fibrosis. However, the ischaemia duration that long enough to cause broad fibrosis shows high mortality rate short does not fibrosis, resulting in large variation progression this experimental model. Inter-operator occurs for I/R severity because procedure complex, which results poor reproducibility subsequent In present study, we developed 8 weeks predictable within days. Three operators...
Visceral adiposity index (VAI) is an indicator of visceral fat accumulation and dysfunction. However, little known about whether VAI associated with worsening renal function (WRF) in the elderly. Therefore, our study aimed to explore association between WRF among elderly population. In total, 5,583 participants (aged ≥ 65 years) who participated annual health checkups at least twice January 2017 July 2021 were enrolled divided into four groups according quartiles. The primary endpoint was...
More and more embedded devices, such as mobile phones, tablet PCs laptops, are used in every field, so huge files need to be stored or backed up into cloud storage. Optimizing the performance of storage is very important for Internet development. This paper presents evaluation open source distributed system, a highly available, distributed, eventually consistent object/blob store from OpenStack computing components. mainly focuses on mechanism well optimization methods process different...
Abstract Background Contrast-induced acute kidney injury (CI-AKI) is a common complication with poor outcomes following coronary angiography (CAG) or percutaneous intervention (PCI). However, no study has explored the population attributable risks (PARs) of CI-AKI risk factors. Therefore, we aimed to identify independent factors and estimate their PARs. Methods We analyzed 3450 consecutive patients undergoing CAG/PCI from prospective cohort in Guangdong Provincial People’s Hospital. was...
Background: Previous studies have established blood pressure (BP) as a pivotal factor influencing no-reflow following primary percutaneous coronary intervention (PCI) in patients with ST-elevation acute infarction (STEMI). However, no relevant study has been conducted to investigate the optimal range of BP associated lowest risk among STEMI so far. Therefore, our objective was evaluate association between pre-PCI and occurrence STEMI. Method: We included 1025 undergoing PCI. The categorized...
Contrast-induced acute kidney injury (CI-AKI) is a common complication of coronary angiography (CAG), which associated with worse prognosis. Some studies indicated β-blockers could preserve renal function among patients myocardial infarction (AMI), but the relationship between and CI-AKI has not been well documented AMI who were undergoing CAG or percutaneous intervention (PCI).In this prospective, observational study, 1,309 PCI consecutively recruited January 2010 December 2013. Patients...
Background: Post-contrast acute kidney injury (PC-AKI) is a severe complication of cardiac catheterization.Emerging evidence indicated that long non-coding RNAs (lncRNAs) could serve as biomarkers for various diseases.However, the lncRNA expression profile and potential in PC-AKI remain unclear.This study aimed to investigate novel early detection PC-AKI.Methods: tissues rats was evaluated through RNA sequencing.Potential were identified human-rat homology analysis, blood filtering verified...