A5054229724- Bone health and osteoporosis research
- Bone health and treatments
- Bariatric Surgery and Outcomes
- Hip and Femur Fractures
- Diet and metabolism studies
- Bone and Joint Diseases
- Vitamin D Research Studies
- Obesity and Health Practices
- Pharmacology and Obesity Treatment
- Pelvic and Acetabular Injuries
- Vitamin C and Antioxidants Research
- Genetic Syndromes and Imprinting
- Hip disorders and treatments
- Parathyroid Disorders and Treatments
- Dental Radiography and Imaging
- Bone Metabolism and Diseases
- Obesity, Physical Activity, Diet
- Gastric Cancer Management and Outcomes
- Bone fractures and treatments
- Dental Implant Techniques and Outcomes
- Medical Imaging and Analysis
- Spine and Intervertebral Disc Pathology
- Diabetes Treatment and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Pharmaceutical Practices and Patient Outcomes
Mayo Clinic
2007-2025
WinnMed
2005-2025
Mayo Clinic in Arizona
2009-2024
Diabetes Australia
2024
American Association of Neurological Surgeons
2023
St. Luke's Hospital
2015
Abstract Congenital generalized lipodystrophy (CGL) is a rare autosomal recessive disorder characterized by near complete absence of adipose tissue from birth. Recently, mutations in 1-acylglycerol-3-phosphate O-acyltransferase 2 (AGPAT2) and Berardinelli-Seip congenital (BSCL2) genes were reported pedigrees linked to chromosomes 9q34 11q13, respectively. There are limited data regarding phenotypic differences between the various subtypes CGL. Furthermore, whether there additional loci for...
OBJECTIVE The goal of this study was to compare different recognized definitions osteoporosis in patients with degenerative lumbar spine pathology undergoing elective spinal fusion surgery determine which patient population should be considered for preoperative optimization. METHODS A retrospective review whom planned at 2 academic medical centers performed, and the rate compared based on definitions. Assessments were made dual-energy x-ray absorptiometry (DXA), CT Hounsfield units (HU),...
Introduction: Bone health optimization is a key component of the preoperative management spine surgery patients, as poor bone quality increases odds mechanical complications. The present study aimed to achieve following: (1) compare relative efficacy current osteoporosis medications in improving quality; (2) identify factors influencing treatment response patients. Methods: Patients treated at single, multisite institution who received were identified. Data gathered on pre- and...
OBJECTIVE The purpose of this study was to determine the effect osteoporosis medications on opportunistic CT-based Hounsfield units (HU). METHODS Spine and nonspine surgery patients were retrospectively identified who had been treated with romosozumab for 3 12 months, teriparatide > denosumab or alendronate months. HU measured in L1–4 vertebral bodies. One-way ANOVA used compare mean change among five treatment regimens. RESULTS In total, 318 (70% women) included, a age 69 years BMI 27...
<h3>Objective:</h3> The objective of this study was to compare the performance US Preventive Services Task Force (USPSTF) recommended WHO Fracture Risk Assessment Tool (FRAX) threshold score 9.3% (calculated without femoral neck bone density) with Simple Calculated Osteoporosis Estimate (SCORE), Self-Assessment (OST), and Instrument (ORAI) identify osteoporosis in younger women. <h3>Methods:</h3> We conducted a retrospective review women ages 50 64 years who underwent dual-energy...
OBJECTIVE Opportunistic Hounsfield unit (HU) determination from CT imaging has been increasingly used to estimate bone mineral density (BMD) in conjunction with assessments dual energy x-ray absorptiometry (DXA). The authors sought compare the effect of teriparatide on HUs across different regions pelvis, sacrum, and lumbar spine, as a surrogate measure for effects lumbosacropelvic instrumentation. METHODS A single-institution retrospective review patients who had treated at least 6 months...
Study Design. Retrospective cohort study. Objective. Hounsfield units (HUs) are known to correlate with clinical outcomes, but no study has evaluated how they biomechanical computed tomography (BCT) and dual-energy x-ray absorptiometry (DXA) measurements. Summary of Background. Low bone mineral density (BMD) represents a major risk factor for fracture poor outcomes following spine surgery. DXA can provide regional BMD measurements limitations. Opportunistic HUs targeted estimates; however,...
OBJECTIVE Hounsfield units (HUs) may better predict biomechanical complications of instrumented fusion than conventional bone quality measures. Typically, noncontrast axial slices are used. This study aims to address the influence reconstruction plane and contrast administration on measured HUs in patients undergoing lumbar spine imaging. METHODS Patients without prior surgery, infection, or tumor were identified for 3 groups: 1) 150 with high-resolution CT, 2) 109 contrast-enhanced 3) 100...