Hiroaki Hiraiwa

ORCID: 0000-0002-1606-7037
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About
Contact & Profiles
Research Areas
  • Cardiovascular Function and Risk Factors
  • Heart Failure Treatment and Management
  • Mechanical Circulatory Support Devices
  • Cardiac Structural Anomalies and Repair
  • Viral Infections and Immunology Research
  • Cardiac Arrest and Resuscitation
  • Cardiomyopathy and Myosin Studies
  • Hemodynamic Monitoring and Therapy
  • Cardiac Imaging and Diagnostics
  • CAR-T cell therapy research
  • Cardiac pacing and defibrillation studies
  • Cardiac Valve Diseases and Treatments
  • COVID-19 Clinical Research Studies
  • Cardiac electrophysiology and arrhythmias
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Cardiovascular Effects of Exercise
  • Sepsis Diagnosis and Treatment
  • Cardiovascular and exercise physiology
  • Sarcoidosis and Beryllium Toxicity Research
  • Atherosclerosis and Cardiovascular Diseases
  • Heart Rate Variability and Autonomic Control
  • Hormonal Regulation and Hypertension
  • Muscle activation and electromyography studies
  • Cancer Immunotherapy and Biomarkers
  • Pulmonary Hypertension Research and Treatments

Nagoya University
2016-2025

Nagoya University Hospital
2019-2024

Nagoya Ekisaikai Hospital
2014-2020

Nagoya City University
2018

Asahi University
2017

Mizuho (Japan)
2017

Abstract Dynamic chest radiography (DCR) can estimate haemodynamic parameters in heart failure (HF). However, no studies have evaluated its ability to determine cardiac systolic function HF. This experimental study investigates the correlation between left ventricular (LV) ejection fraction (LVEF) and DCR image Ninety-one patients with acute HF (median age, 58 years; males, 75%) (cardiologist diagnosis using Framingham criteria) underwent transthoracic echocardiography after treatment for...

10.1007/s10554-025-03332-x article EN cc-by The International Journal of Cardiovascular Imaging 2025-01-25

Novel coronavirus disease 2019 (COVID-19) refers to infection with the severe acute respiratory syndrome 2 (SARS-CoV-2) pathogen, and has spread pandemic levels since its inception in December 2019. While several risk factors for presentation have been identified, clinical course end-stage renal (ESRD) patients on maintenance hemodialysis COVID-19 unclear. Previous studies revealed that some antiviral agents may be effective against general population, but pharmacokinetics pharmacodynamics...

10.1007/s13730-020-00534-1 article EN other-oa CEN Case Reports 2020-09-17

Left ventricular reverse remodelling (LVRR) is a well-established predictor of good prognosis in patients with dilated cardiomyopathy (DCM). The prediction LVRR important when developing long-term treatment strategy. This study aimed to assess the clinical predictors and establish scoring system for predicting DCM that can be used at any institution. We consecutively enrolled 131 assessed LVRR. was defined as an absolute increase left ejection fraction (LVEF) from ≥10% final value >35%,...

10.1002/ehf2.13216 article EN cc-by-nc ESC Heart Failure 2021-01-20

A 48-year-old woman suffered from cardiogenic shock with fulminant myocarditis following the second dose of COVID-19 vaccine (mRNA-1273). Venoarterial extracorporeal membrane oxygenation and Impella support were essential in achieving hemodynamic stability. Endomyocardial biopsy revealed lymphocytic infiltration predominant immunostaining for CD8- CD68-positive cells. The left ventricular ejection fraction improved significantly after treatment mechanical circulatory support. Myocarditis...

10.1016/j.cjco.2022.02.004 article FR cc-by CJC Open 2022-02-13

The number of older people in Japan is increasing more quickly than other countries; with this aging society, the elderly patients hospitalized for acute heart failure (HF) also increasing. treatment and prognosis HF may be changing, but there are insufficient recent data, especially octogenarian patients.

10.1253/circj.cj-24-0299 article EN Circulation Journal 2024-09-05

External outflow graft obstruction (OGO) in durable left ventricular assist devices (LVADs) is a rare but critical complication. Detecting external OGO can be challenging because of its nonspecific symptoms and wide variety differential diagnoses. We report the case 45 year old man with LVAD admitted complaints recurrent syncope frequent low-flow alarms. Laboratory tests chest radiography revealed no specific findings. Transthoracic echocardiography via subcostal approach an compressed by...

10.1097/mat.0000000000002406 article EN ASAIO Journal 2025-03-03

Despite the efficacy of many therapies for heart failure, it remains a leading cause morbidity and mortality worldwide, with patients progressing to advanced stages condition. Since standard treatment failure includes small-molecule drugs targeting G protein-coupled receptors (GPCRs), GPCRs are still considered novel targets diagnosis cardiovascular diseases. Corticotropin-releasing hormone receptor 2, highly expressed GPCR in cardiomyocytes, its ligand, urocortin2 (UCN2), have been...

10.1038/s41598-025-99509-4 article EN cc-by-nc-nd Scientific Reports 2025-04-24

Dynamic chest radiography (DCR) can estimate haemodynamic parameters in patients with heart failure (HF). Atrial fibrillation (AF) often coexists HF; however, owing to its sometimes paroxysmal nature and minimal or absent symptoms, many AF remain undiagnosed. Additional tools for diagnosis may be beneficial; therefore, we evaluated the ability of DCR distinguish HF sinus rhythm (SR) from those AF. In this small-sample pilot study, 20 (median age, 67 years; males, 85%) underwent 12-lead...

10.1186/s12872-025-04820-7 article EN cc-by-nc-nd BMC Cardiovascular Disorders 2025-05-19

Dynamic chest radiography allows for non-invasive cardiopulmonary blood flow assessment. However, data on its use heart failure hemodynamic assessment are scarce. We utilized dynamic to estimate hemodynamics.Twenty patients (median age, 67 years; 17 men) underwent and right catheterization. The analyzed images were 16-bit (grayscale range: 0-65,535). Right atrial, pulmonary artery, left ventricular apex pixel values (average of the grayscale all pixels within a region interest) measured....

10.1016/j.ejrad.2023.110729 article EN cc-by-nc-nd European Journal of Radiology 2023-02-04

A 53-year-old woman with no significant medical history developed cardiogenic shock 4 days after receiving the second dose of COVID-19 mRNA vaccine (BNT162b2, Pfizer/BioNtech). The patient required extracorporeal membrane oxygenation and an Impella device. Based on hemoconcentration, decreased plasma protein levels, pathologic findings in myocardial specimens, was diagnosed vaccination-induced fulminant systemic capillary leak syndrome (SCLS) severe cardiac dysfunction. This case highlights...

10.1016/j.cjco.2022.03.008 article FR cc-by-nc-nd CJC Open 2022-03-24
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