A5029456417- Multiple Sclerosis Research Studies
- Memory and Neural Mechanisms
- Neuroscience and Neuropharmacology Research
- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Neural dynamics and brain function
- Computational Drug Discovery Methods
- Retinal Development and Disorders
- Stress Responses and Cortisol
- Functional Brain Connectivity Studies
- Neuroendocrine regulation and behavior
- Photoreceptor and optogenetics research
- Receptor Mechanisms and Signaling
- Ultrasound Imaging and Elastography
National Research Council
2024-2025
Inserm
2024-2025
University of Palermo
2022-2025
Institut de Neurosciences des Systèmes
2024-2025
ABSTRACT Multiple sclerosis (MS) is a clinically heterogeneous, multifactorial autoimmune disorder affecting the central nervous system. Structural damage to myelin sheath, resulting in consequent slowing of conduction velocities, key pathophysiological mechanism. In fact, velocities are closely related degree myelination, with thicker sheaths associated higher velocities. However, how intensity structural lesions translates nerve delays not known. this work, we use large‐scale brain models...
Background Brain connectome fingerprinting represents a recent and valid approach in assessing individual identifiability on the basis of subject-specific brain functional connectome. Although this methodology has been tested validated several neurological diseases, its performance, reliability reproducibility healthy individuals poorly investigated. In particular, impact changes connectivity, induced by different phases menstrual cycle (MC), remains unexplored. Furthermore, although...
Hippocampal Place Cells (PCs) are pyramidal neurons showing spatially localized firing when an animal gets into a specific area within environment. Because of their obvious and clear relation with cognitive functions, operations modulations intensely studied experimentally. However, although lot data have been gathered since discovery, the cellular processes that interplay to turn hippocampal neuron Cell still not completely understood. Here, we used morphologically biophysically detailed...
Abstract Multiple sclerosis (MS) is a clinically heterogeneous, multifactorial autoimmune disorder affecting the central nervous system. Structural damage to myelin sheath, resulting in consequent slowing of conduction velocities, key pathophysiological mechanism. In fact, velocities are closely related degree myelination, with thicker sheaths associated higher velocities. However, how intensity structural lesions translates nerve delays not known. this work, we use large-scale brain models...