- Cardiovascular and exercise physiology
- Heart Rate Variability and Autonomic Control
- Sports Performance and Training
- Chemotherapy-induced cardiotoxicity and mitigation
- Cardiovascular Health and Disease Prevention
- Spaceflight effects on biology
- Cardiovascular Function and Risk Factors
- Cardiovascular Effects of Exercise
- Exercise and Physiological Responses
- Muscle activation and electromyography studies
- Hemodynamic Monitoring and Therapy
- Cardiovascular and Diving-Related Complications
- Thermoregulation and physiological responses
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Disease and Adiposity
- Pulmonary Hypertension Research and Treatments
- Muscle metabolism and nutrition
- Cardiac Imaging and Diagnostics
- High Altitude and Hypoxia
- Cancer Treatment and Pharmacology
- Antioxidant Activity and Oxidative Stress
- Peripheral Artery Disease Management
- Optical Imaging and Spectroscopy Techniques
- Sports injuries and prevention
- Non-Invasive Vital Sign Monitoring
Kansas State University
2016-2025
The University of Kansas Cancer Center
2018-2024
Cancer Research Center
2018-2024
Clinical Research Consortium
2021
Committee on Publication Ethics
2019
University of Oklahoma
2014-2018
Iowa State University
2016
Western Sydney University
2011
Bradford Royal Infirmary
1991
Cardiac involvement among hospitalized patients with severe coronavirus disease 2019 (COVID-19) is common and associated adverse outcomes. This study aimed to determine the prevalence clinical implications of COVID-19 cardiac in young competitive athletes.In this prospective, multicenter, observational cohort data from 42 colleges universities, we assessed prevalence, characteristics, outcomes collegiate athletes United States. Data were collected September 1, 2020, December 31, 2020. The...
Summary Introduction Blood flow restriction ( BFR ), the application of external pressure to occlude venous return and restrict arterial inflow, has been shown increase muscular size strength when combined with low‐load resistance exercise. in research setting uses a wide range pressures, applying based upon an individual's systolic or percentage occlusion pressure; not directly determined reduction blood flow. The relationship between relative established. Purpose To measure arm under...
It was previously (Monod H, Scherrer J. Ergonomics 8: 329-338, 1965) postulated that blood flow occlusion during exercise would reduce critical power (CP) to 0 Watts (W), while not altering the curvature constant (W'). We empirically assessed influence of on CP, W', and muscle oxygenation characteristics. Ten healthy men (age: 24.8 ± 2.6 yr; height: 180 5 cm; weight: 84.6 10.1 kg) completed four constant-power handgrip tests both control (control) (occlusion) for determination power-duration...
It is unknown whether the astronaut occupation or exposure to microgravity influences risk of long-term cardiovascular disease (CVD). This study explored effects being a career National Aeronautics and Space Administration (NASA) on for clinical CVD end points.During Longitudinal Study Astronaut Health, data were collected 310 NASA astronauts 981 nonastronaut employees. The nonastronauts matched age, sex, body mass index, evaluate acute chronic morbidity mortality. primary outcomes...
Background: The goal of this work was to create a sharable dataset heart-driven signals, including ballistocardiograms (BCGs) and time-aligned electrocardiograms (ECGs), photoplethysmograms (PPGs), blood pressure waveforms. Methods: A custom, bed-based ballistocardiographic system is described in detail. Affiliated cardiopulmonary signals are acquired using GE Datex CardioCap 5 patient monitor (which collects ECG PPG data) Finapres Medical Systems Finometer PRO provides continuous...
Importance The American Heart Association’s Predicting Risk of Cardiovascular Disease Events (PREVENT) equations were developed to extend and improve on previous cardiovascular disease (CVD) risk assessments for the purpose treatment initiation patient-clinician communication. Objective To assess prognostic capabilities, calibration, discrimination PREVENT in a study sample representative noninstitutionalized, US general population. Design, Setting, Participants This used data from National...
Physical activity (PA), especially vigorous-intensity PA, has been shown to be related pain sensitivity. The relationship among PA levels and types on endogenous inhibition after exercise, termed exercise-induced hypoalgesia (EIH), remains unclear.This studied examined the EIH response pressure stimuli college-age women of differing levels.Fifty were tested. Pressure threshold (PPT) values assessed before immediately isometric handgrip exercise exhaustion in right left forearms....
Breast cancer patients' maximal O2 uptake (V̇O2max) values average 60-80% of age-predicted which is often attributed to adjuvant therapy rather than risk factors, comorbidities, or the tumor and associated factors (e.g., pro-inflammatory cytokines). It crucial understand physiological mechanisms behind exercise intolerance in breast patients enhance targeted interventions; however, effect cancer, as an isolated condition on V̇O2max, tolerance, resting cardiac function has not been...
It has previously been suggested that the respiratory compensation point (RCP) and critical speed (CS) parameters are equivalent and, therefore, like CS, RCP demarcates boundary between heavy- severe-intensity domains. However, these findings equivocal therefore must be interpreted cautiously. Thus, we examined relationship CS across a wide range of subject fitness levels, in an attempt to determine if equivalent. Forty men 30 women (age: 23.2 ± 2.5 year, height: 174 10 cm, body mass: 74.1...
Caffeine ingestion improves endurance time trial performance. However, the ergogenic mechanism of action remains unresolved. One potential explanation for caffeine's performance-enhancing effect is an improvement in work a given amount muscle pain.To test this hypothesis, participants performed two studies which they regulated exercise intensity based on feelings pain.Thirteen young men were asked to regulate "moderate" pain (a "3" 0-10 scale). After three familiarization trials, either...
This paper investigated the effects of unaccustomed eccentric exercise-induced muscle damage (EIMD) on macro- and microvascular function. We tested hypotheses that resting local systemic endothelial-dependent flow-mediated dilation (FMD) reactivity would decrease, be altered, during ramp exercise, peripheral O2 extraction, evaluated via near-infrared-derived spectroscopy (NIRS) derived deoxygenated hemoglobin + myoglobin ([HHb]), distorted following EIMD. In 13 participants, measurements...
We have previously predicted that the decrease in maximal oxygen uptake (V̇o 2max ) accompanies time microgravity reflects decrements both convective and diffusive O 2 transport to mitochondria of contracting myocytes. The aim this investigation was therefore quantify relative changes (Q̇o diffusing capacity (Do following long-duration spaceflight. In nine astronauts, resting hemoglobin concentration ([Hb]), V̇o , cardiac output (Q̇ Tmax ), differences arterial venous contents ([Formula: see...
Exercise intolerance is a primary symptom of heart failure (HF); however, the specific contribution central and peripheral factors to this not well described. The hyperbolic relationship between exercise intensity time exhaustion (speed-duration relationship) defines tolerance but underused in HF. We tested hypotheses that critical speed (CS) would be reduced HF, resting functional measurements correlate with CS, greatest HF-induced dysfunction occur more oxidative muscle. Multiple...
Limb blood flow increases linearly with exercise intensity; however, invasive measurements of muscle microvascular during incremental have demonstrated submaximal plateaus. We tested the hypotheses that 1) brachial artery (Q̇BA) would increase increasing intensity until task failure, 2) index flexor digitorum superficialis (BFIFDS) measured noninvasively via diffuse correlation spectroscopy plateau at a work rate, and 3) oxygenation characteristics (total-[heme], deoxy-[heme], percentage...