- Cardiac electrophysiology and arrhythmias
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Heart Rate Variability and Autonomic Control
- Cardiac Imaging and Diagnostics
- ECG Monitoring and Analysis
- Cardiovascular Function and Risk Factors
- Cardiovascular Syncope and Autonomic Disorders
- Heart Failure Treatment and Management
- Cardiovascular Effects of Exercise
- Advanced MRI Techniques and Applications
- Cardiovascular Disease and Adiposity
- Acute Myocardial Infarction Research
- Cardiomyopathy and Myosin Studies
- Non-Invasive Vital Sign Monitoring
- Cardiac Arrest and Resuscitation
- Ion channel regulation and function
- Cardiac Ischemia and Reperfusion
- Acute Ischemic Stroke Management
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Valve Diseases and Treatments
- Legal principles and applications
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Health and Risk Factors
University of Miami
2016-2025
University of Miami Health System
2025
Northwestern University
2012-2024
Jackson Memorial Hospital
2016-2024
Renal Research Institute
2020-2024
Rush University
2024
Jeffrey Modell Foundation
2006-2020
Prince George's Hospital Center
2017
Royal Brompton Hospital
2017
Lung Institute
2017
Patients with nonischemic dilated cardiomyopathy are at substantial risk for sudden death from cardiac causes. However, the value of prophylactic implantation an implantable cardioverter–defibrillator (ICD) to prevent in such patients is unknown.
This study aimed to determine whether QRS morphology identifies patients who benefit from cardiac resynchronization therapy with a defibrillator (CRT-D) and it influences the risk of primary secondary end points in enrolled Multicenter Automatic Defibrillator Implantation Trial-Cardiac Resynchronization Therapy (MADIT-CRT) trial.Baseline 12-lead ECGs were evaluated regard morphology. Heart failure event or death was point trial. Death, heart event, ventricular tachycardia, fibrillation...
Sudden cardiac death (SCD) remains a daunting problem. It is major public health issue for several reasons: from its prevalence (20% of total mortality in the industrialized world) to devastating psycho-social impact on society and families victims often still their prime, it represents challenge medicine, especially cardiology. This text summarizes discussions opinions group investigators with long-standing interest this field. We addressed occurrence SCD individuals apparently healthy,...
Background— We hypothesized that combined assessment of factors are associated with favorable reverse remodeling after cardiac resynchronization-defibrillator therapy (CRT-D) can be used to predict clinical response the device. Methods and Results— The study population comprised 1761 patients enrolled in Multicenter Automatic Defibrillator Implantation Trial With Cardiac Resynchronization Therapy (MADIT-CRT). Best-subset regression analysis was performed identify echocardiographic (defined...
Cardiac involvement among hospitalized patients with severe coronavirus disease 2019 (COVID-19) is common and associated adverse outcomes. This study aimed to determine the prevalence clinical implications of COVID-19 cardiac in young competitive athletes.In this prospective, multicenter, observational cohort data from 42 colleges universities, we assessed prevalence, characteristics, outcomes collegiate athletes United States. Data were collected September 1, 2020, December 31, 2020. The...
BACKGROUND The utility of transcatheter application radiofrequency energy to eliminate atrioventricular nodal reentrant tachycardia (AVNRT) was investigated. METHODS AND RESULTS Thirty-nine patients (mean age, 53 +/- 20 years; range 14-86 years) with medically refractory AVNRT underwent perinodal ablation energy. A custom-designed 6F catheter a large (3-mm-long) distal electrode and interelectrode pacing 2 mm used in the majority cases. for initially positioned across tricuspid anulus obtain...
In a prospective cohort study, associations of resting heart rate with risk coronary, cardiovascular disease, cancer, and all-cause mortality in age-specific cohorts black white men women were examined over 22 years follow-up. Participants employees from 84 companies organizations the Chicago, Illinois, area who volunteered for screening examination. included 9,706 aged 18–39 years, 7,760 40–59 1,321 60–74 6,928 6,915 1,151 at baseline examination 1967–1973. Vital status was ascertained...
Baroreflex-mediated parasympathetic stimulation has variable effects on heart rate variability (HRV). We postulated that a quadratic function would describe the relationship between HRV and effect better than linear function.Twenty-nine normal volunteers (15 women; mean age 39+/-12 years) were studied after beta-adrenergic blockade with intravenous propranolol. Five-minute ECG recordings made during graded infusions of phenylephrine nitroprusside to achieve baroreflex-mediated increases...
The objective of this study was to evaluate whether heart rate variability (HRV) can be used as an index parasympathetic reactivation after exercise. Heart recovery exercise has recently been shown have prognostic significance and postulated related abnormal tone. Ten normal subjects [5 men 5 women; age 33 +/- yr (mean SE)] exercised their maximum capacity, 12 (10 2 61 10 yr) with coronary artery disease for 16 min on two separate occasions, once in the absence atropine (0.04 mg/kg)...
There are complex interactions between the sympathetic and parasympathetic nervous system inputs to sinus node. The concept of "sympathovagal balance" reflects autonomic state resulting from influences. Despite widespread usage a variety heart rate (HR) variability parameters as indexes sympathovagal balance, no index has been validated measure balance. This study evaluated utility HR, HR variability, new parameter termed vagal-sympathetic effect (VSE) ideal had satisfy following criteria:...