A5100754750- Acute Myeloid Leukemia Research
- Dementia and Cognitive Impairment Research
- Nutrition and Health in Aging
- Frailty in Older Adults
- Physical Activity and Health
- Health and Wellbeing Research
- Stroke Rehabilitation and Recovery
- Balance, Gait, and Falls Prevention
- Psychosocial Factors Impacting Youth
- Acute Lymphoblastic Leukemia research
- Body Composition Measurement Techniques
- Diverse Approaches in Healthcare and Education Studies
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Cardiovascular and exercise physiology
- Health disparities and outcomes
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Organic Electronics and Photovoltaics
- Neuroinflammation and Neurodegeneration Mechanisms
- Cerebral Palsy and Movement Disorders
- Technology Adoption and User Behaviour
- Optical Imaging and Spectroscopy Techniques
- Sleep and related disorders
- Organic Light-Emitting Diodes Research
- Cardiovascular Health and Disease Prevention
Dong-A University
2016-2025
Korea University
2021-2025
Kyung Hee University
2025
Chonnam National University Hwasun Hospital
2024
Korea Photonics Technology Institute
2019-2024
Chonnam National University
2024
National Center for Geriatrics and Gerontology
2013-2023
Sungkyunkwan University
2014-2023
Chonnam National University Hospital
2023
Samsung Medical Center
2014-2023
To examine the effects of a multicomponent exercise program on cognitive function older adults with amnestic mild impairment (aMCI). Design: Twelve months, randomized controlled trial; Setting: Community center in Japan; Participants: Fifty (27 men) aMCI ranging age from 65 to 93 years (mean age, 75 years); Intervention: Subjects were into either (n = 25) or an education control group 25). exercised under supervision physiotherapists for 90 min/d, 2 d/wk, total 80 times over 12 months. The...
This study aimed to investigate the association between a virtual reality (VR) intervention program and cognitive, brain physical functions in high-risk older adults. In randomized controlled trial, we enrolled 68 individuals with mild cognitive impairment (MCI). The MCI diagnosis was based on medical evaluations through clinical interview conducted by dementia specialist. Cognitive assessments were performed neuropsychologists according standardized methods, including Mini-Mental State...
This study sought to confirm the test-retest reliability and validity of National Center for Geriatrics Gerontology functional assessment tool (NCGG-FAT), a newly developed multidimensional neurocognitive function using tablet personal computer (PC).This included 20 community-dwelling older adults (9 females, aged 65-81 years). Participants were administered NCGG-FAT twice, separated by approximately 30 days determine reliability. To test measure, participants underwent established...
Objective: The clinical relationship between brain-derived neurotrophic factor (BDNF) and cognitive function or mild impairment (MCI) is not well understood. purpose of this study was to identify the serum BDNF MCI, determine whether level might be a useful biomarker for assessing risk MCI in older people.Materials Methods: A total 4463 individuals aged 65 years (mean age 72 years) participating study. We measured performance battery neuropsychological tests; concentration.Results: Eight...
New highly twisted and rigid blue materials composed of anthracene with xylene as the core unit either naphthalene or phenyl end units were synthesized. Non-doped devices using BDNA displayed 5.26% maximum external quantum efficiency CIE color coordinates (x, y: 0.159, 0.072).
Aim Several operative definitions and screening methods for sarcopenia have been proposed in previous studies; however, the opinions of researchers still differ. We compared prevalence using two different algorithms: (i) E uropean working group on older people ( EWGSOP )‐suggested algorithm gait speed as first step; (ii) muscle mass strength algorithm. Methods A population‐based, cross‐sectional survey adults aged over 65 years was carried out. Data a total 4811 participants were available...
Chronic mucocutaneous candidiasis (CMC) is a heterogeneous group of primary immunodeficiency diseases characterized by chronic and recurrent Candida infections the skin, nails, oropharynx. Gain-of-function mutations in STAT1 were very recently shown to be responsible for autosomal-dominant or sporadic cases CMC. The reported have been exclusively localized coiled-coil domain, resulting impaired dephosphorylation STAT1. However, recent crystallographic analysis direct mutagenesis experiments...
The microbiota of the gastrointestinal tract (GIT) constitutes major part total human microbiome and is considered to be an important regulator health host metabolism. Numerous investigations in recent years have focused on connection between metabolic diseases such as obesity, type II diabetes atherosclerosis. Yet, little known about impact probiotic consumption GIT microbial population potential effect chronic diseases. In this study, modulation community murine small intestine resulting...
Greater physical activity (PA) is associated with better memory performance and greater hippocampal volume in older adults. However, most studies to date assessed PA via questionnaires thereby lacked objective characterization of (eg, intensity, duration, etc.). Thus, we currently do not have a comprehensive understanding characteristics that are important for neuroprotection, especially among adults mild cognitive impairment (MCI). using triaxial accelerometers, examined the association...
Abstract Background The aim of this study was to describe the age‐dependent changes in parameters physical performance and body composition Japanese older adults who are independently dwelling community. We also examined whether differ among parameters. Methods Cross‐sectional data from 10 092 community‐dwelling (mean age 73.6 years; 5296 women) were analyzed. measures included hand‐grip strength, five‐times‐sit‐to‐stand test, walking speed. Body (body weight, fat mass, appendicular skeletal...
Aim Cognitive impairment can negatively affect driving performance and increase the risk of errors, leading to vehicle crashes. We used a population‐based survey identify prevalence cognitive impairments in older drivers. Methods A total 10 073 adults were enrolled N ational C enter for G eriatrics erontology – S tudy eriatric yndromes. characterized general using Mini‐Mental State Examination ( MMSE ). also erontology‐ F unctional ssessment T ool, which includes six tasks assess word list...
This study aimed to investigate the association between a dual-task intervention program and cognitive physical functions. In randomized controlled trial, we enrolled 49 individuals with MCI. The MCI diagnosis was based on medical evaluations through clinical interview conducted by dementia specialist. Cognitive assessments were performed neuropsychologists according standardized methods, including MMSE modified Alzheimer's disease Assessment Scale-Cognitive Subscale (ADAS-Cog), both at...
The present study examined whether a culture-based virtual reality (VR) training program is feasible and tolerable for patients with amnestic mild cognitive impairment (aMCI), it could improve function in these patients. Twenty-one outpatients aMCI were randomized to either the VR-based group or control 1∶1 ratio. participated 30 min/day, two days/week, three months (24 times). was designed based on Korean traditional culture used attention, processing speed, executive memory conditions...
We investigated the effectiveness of virtual-reality-based cognitive training (VRCT) and exercise on brain, cognitive, physical activity older adults with mild impairment (MCI).This study included 99 participants (70.8 ± 5.4) MCI in VRCT, exercise, control groups. The VRCT consisted a series games targeting different brain functions such as executive function, memory, attention. Twenty-four sessions (three days/week) were performed, each session was 100 min long. Exercise intervention...