A5073547910- Ophthalmology and Visual Impairment Studies
- Corneal surgery and disorders
- Glaucoma and retinal disorders
- Ocular Surface and Contact Lens
- Retinal Diseases and Treatments
- Ergonomics and Musculoskeletal Disorders
- Visual perception and processing mechanisms
- Retinopathy of Prematurity Studies
- Ophthalmology and Eye Disorders
- Intraocular Surgery and Lenses
- Spatial Cognition and Navigation
- Ophthalmology and Visual Health Research
- Chemical Looping and Thermochemical Processes
- Color perception and design
- Ocular and Laser Science Research
- Retinal Imaging and Analysis
- Circadian rhythm and melatonin
- Genetics, Aging, and Longevity in Model Organisms
- Virtual Reality Applications and Impacts
- Photoreceptor and optogenetics research
- Retinal Development and Disorders
- Gaze Tracking and Assistive Technology
- Surface Roughness and Optical Measurements
- Coal Properties and Utilization
- Ocular Diseases and Behçet’s Syndrome
Affiliated Eye Hospital of Wenzhou Medical College
2012-2025
Wenzhou Medical University
2016-2025
Inner Mongolia International Mongolian Hospital
2024
Heilongjiang Provincial Hospital
2024
National Clinical Research Center for Digestive Diseases
2021-2023
Harbin University
2022
Essilor (Germany)
2015-2021
He Eye Hospital
2021
Ministry of Education of the People's Republic of China
2021
Babcock & Wilcox (United States)
2020
Reducing myopia progression can reduce the risk of associated ocular pathologies.To evaluate whether spectacle lenses with higher lenslet asphericity have a control efficacy throughout 2 years.This double-masked randomized clinical trial was conducted between July 2018 and October 2020 at Eye Hospital Wenzhou Medical University in Wenzhou, China. Children aged 8 to 13 years cycloplegic spherical equivalent refraction (SER) -0.75 D -4.75 astigmatism less than -1.50 were recruited. A data...
Aims To evaluate the 1-year efficacy of two new myopia control spectacle lenses with lenslets different asphericity. Methods One hundred seventy schoolchildren aged 8–13 years −0.75 D to −4.75 were randomised receive highly aspherical (HAL), slightly (SAL), or single-vision (SVL). Cycloplegic autorefraction (spherical equivalent refraction (SER)), axial length (AL) and best-corrected visual acuity (BCVA) measured at baseline 6-month intervals. Adaptation compliance questionnaires...
Myopia is the most common cause of visual impairment worldwide,1Holden B.A. Fricke T.R. Wilson D.A. et al.Global prevalence myopia and high temporal trends from 2000 through 2050.Ophthalmology. 2016; 123: 1036-1042Abstract Full Text PDF PubMed Scopus (2814) Google Scholar younger age at onset may progress to myopia.2Gwiazda J. Hyman L. Dong L.M. al.Factors associated with after 7 years follow-up in Correction Evaluation Trial (COMET) cohort.Ophthalmic Epidemiol. 2007; 14: 230-237Crossref...
To investigate myopia control efficacy in children who continued wearing spectacle lenses with highly aspherical lenslets (HAL) or switched from slightly (SAL) and single-vision (SVL) to HAL for 1 year after a 2-year trial.This was 1-year extension of randomized clinical trial.Of 54 had worn 2 years, 52 (HAL1 group), the 53 51 originally SAL SVL, 48 (HAL2 HAL3 groups) 3, respectively. A new SVL (nSVL) group 56 recruited, matched age, sex, cycloplegic spherical equivalent refraction (SER),...
Abstract Background Myopia is the most common visual impairment in children and adolescents worldwide. This study described an economical effective population-based screening pipeline performed project of a million scale myopia survey (CAMS), which will shed light on further from level epidemiology precision medicine. Methods We developed novel pattern, intelligent process internet-based information transmission analysis system to carry out consisting school Wenzhou, China. The examination...
Purpose: To evaluate the effect of low-concentration (0.01% and 0.05%) atropine eyedrops on ocular surface characteristics in young adults. Methods: Twenty-six myopic students aged 18 to 30 years were randomly assigned receive either 0.01% or 0.05% once nightly for 14 days, followed by cessation, with a ≥14-day interval between each administration. Assessments conducted one, two, seven, days after using corresponding timepoints cessation. Tear meniscus height first average noninvasive...
Purpose: This study aimed to evaluate short-term visual performance and optical quality of three different lenslet configurations on myopia control spectacle lenses. Materials Methods: utilized a cross-over design. Distance acuity (VA) was measured in 50 myopic children; contrast sensitivity (CS) 36 children. For each test, four lenses were evaluated random order: single-vision lens (SVL), with concentric rings highly aspherical lenslets (HAL), slightly (SAL), honeycomb configuration...
Objective Spectacle lenses with highly aspherical lenslets (HAL) and slightly (SAL) showed effective myopia control. This study was to investigate their effects on macular choroidal thickness (ChT) in myopic children. Methods Exploratory analysis from a 2-year, double-masked, randomised trial. 170 children aged 8–13 years between −0.75D −4.75D, astigmatism of 1.50D or less, anisometropia 1.00D less were recruited. Participants randomly assigned 1:1:1 ratio receive HAL, SAL single vision...
With increasing axial length and myopia progression, the micro-structure of retina choroid gradually changes. Our study describes longitudinal changes in retinal choroidal thickness school-aged children with explores relationship between progression.An exploratory analysis a randomized trial was performed. Children (n = 168, aged 7 to 12 years) from - 0.75 dioptre (D) 4.00 D were enrolled this prospective study. Cycloplegic refraction, (AL), thicknesses measured at baseline 1- 2-year...
To study the effect of blur adaptation on accommodative variability, responses and pupil diameters in myopes (n = 22) emmetropes 19) were continuously measured before, during, after exposure to defocus blur. Accommodative pupillary response measurements made by an autorefractor during a monocular reading exercise. The text was presented computer screen at 33 cm viewing distance with rapid serial visual presentation paradigm. After baseline testing 5-min rest, induced wearing either optimally...
To investigate near-vision posture in Chinese myopic schoolchildren and compare during different tasks (i.e., playing video games, reading, writing).The study investigated 120 children (grades 1 through 6 aged to 13 years). An electromagnetic motion-tracking system was used for continuous measurements of the working distance head declination subjects while they were games or reading writing at a desk. The documents adjusted by grade level grades 2, 3 4, 5 6). For analysis, grouped two...
Abstract This study shows accommodative accuracy and distance accommodation facility in myopic children do not play a role myopia progression. In 144 subjects, the monocular (DAF) continuous stimulus–response curves (ASRCs) were measured at enrolment. Retrospective prospective refraction with regard to enrolment visit obtained from outpatient database system based on noncycloplegic subjective spherical equivalent (SER). The rate of progression was first derivative Gompertz function, which...
This prospective study assessed the influence of wearing and then discontinuing orthokeratology (OK) lenses on retinal shape peripheral refraction in myopic children.Fifty-eight children (age 8-12 years) were equally divided into an OK group a single vision spectacles (SVS) group. After 12 months OK, it was discontinued for 1 month. Peripheral eye length (PEL), relative (RPR), corneal parameters measured right nasal temporal sides at baseline, 6 months, (13 group) visits.In SVS group, faster...
Abstract Purpose The onset and progression of myopia can occur during adulthood, suggesting that should be managed in young adults. Low‐concentration atropine eye drops have shown promising efficacy control. This study aimed to evaluate the impact 0.01% 0.05% on visual performance university students. Methods Twenty‐six myopic students aged 18–30 years received random order. Atropine were administered once a night both eyes for 14 days, with minimum 14‐day washout period between...
Abstract Purpose Spectacle lenses with highly aspherical lenslets (HAL) have been shown to slow myopia progression and axial length (AL) elongation effectively. The effects of HAL on peripheral eye (PEL) refraction (PR) were investigated in children who continued wearing or switched from single‐vision spectacle (SVL) slightly (SAL) HAL. Methods Fifty‐two participants had worn for 2 years their use (HAL group), while 51 48 originally SAL SVL (SAL‐HAL SVL‐HAL groups, respectively) Year 3. A...
Abstract Purpose To compare peripheral defocus, higher-order aberrations (HOAs), and contrast visual acuity (CVA) in myopic children wearing orthokeratology (OK) lenses multifocal soft contact (MSCLs) designed with highly addition. Methods This is a prospective, nonrandomized, controlled study. Subjects at 8 to 13 years of age spherical equivalent refraction from − 1.00 5.00 dioptres (D) were included the OK group ( n = 30) MSCL 23). Relative corneal defocus (RPCD) relative (RPR) measured...
To investigate the impact of wearing spectacle lenses with highly aspherical lenslets (HAL) for 3 years and switching from single-vision (SVL) to HAL on choroidal thickness (ChT).
To evaluate myopia control efficacy in myopic children wearing spectacle lenses with highly aspherical lenslets (HAL) for 5 years. This is a randomized, double-masked extended trial. Myopic aged 8 to 13 years who were originally allocated the HAL group 2-year clinical The underwent 5-year assessment progression using cycloplegic spherical equivalent refraction (SER) and axial length (AL). An extrapolated single-vision (ESVL) was used as group. elongation of ESVL calculated based on data from...
Purpose: To assess the short-term impact of different types contact lenses on accommodation in same group myopic children compared with single-vision spectacle lenses. Methods: Thirty aged 10.2 ± 1.5 years were enrolled. Each participant was corrected four modalities following sequence: spectacles (SVSP), soft lens (SVSCL), a high-addition multifocal (MFSCL), and orthokeratology (OKL). Measurements included dynamic accommodative stimulus–response curve (ASRC), distance facility (DAF),...
Abstract Purpose To investigate whether the treatment zone (TZ) decentration in orthokeratology (OK) lenses affects retinal expansion Chinese children with myopia. Methods Children aged 8 to 13 years ( n = 30) were assessed over months comprising 12 of OK lens wear followed by discontinuation for 1 month. Corneal topography was measured at 0, 1, 3, 6, 9, and months. TZ calculated, subjects subdivided into a small group (group S) large L) based on median value weighted average (d ave )....
•Myopia onset was closely related to ocular indicators.•Single spherical equivalent refraction performed poorly in predicting myopia among Chinese schoolchildren.•An online risk calculator developed predict incident schoolchildren. PurposeMyopia is a major public health issue and occurs at young ages. Apart from its high prevalence, results costs irreversible blinding diseases. Accurate prediction of the crucial for precise prevention. We aimed develop validate an effective nomogram...
DNA methyltransferase 3B (DNMT3B) is critically involved in de novo methylation and genomic stability, while the regulatory mechanism liver largely unknown. We previously reported that diurnal variation occurs mRNA expression of Dnmt3b adult mouse liver. The aim this study was to determine underlying pattern. highest level lowest were confirmed occur at dawn afternoon, respectively, pattern closely coincided with Bmal1. Since developed weaning scheduled feeding separate cycle from light/dark...