Carmen Pérez‐Enríquez
A5046910488- Epilepsy research and treatment
- Functional Brain Connectivity Studies
- Neuroscience and Neuropharmacology Research
- Dementia and Cognitive Impairment Research
- Advanced MRI Techniques and Applications
- Fetal and Pediatric Neurological Disorders
- Neurobiology of Language and Bilingualism
- EEG and Brain-Computer Interfaces
- Neurological disorders and treatments
- Blood Pressure and Hypertension Studies
- Aging, Health, and Disability
- Psychosomatic Disorders and Their Treatments
- Memory and Neural Mechanisms
- Neural dynamics and brain function
- Cognitive Functions and Memory
- Glioma Diagnosis and Treatment
- Atomic and Subatomic Physics Research
- Health Systems, Economic Evaluations, Quality of Life
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Pharmacological Effects and Toxicity Studies
- Behavioral and Psychological Studies
- Metabolism and Genetic Disorders
- Developmental and Educational Neuropsychology
- Neural and Behavioral Psychology Studies
- Advanced Neuroimaging Techniques and Applications
Hospital Del Mar
2018-2025
Hospital de Manises
2025
Hospital del Mar Research Institute
2021-2022
Municipal Institute for Medical Research
2018
Barcelona Biomedical Research Park
2018
Abstract One outstanding challenge for machine learning in diagnostic biomedical imaging is algorithm interpretability. A key application the identification of subtle epileptogenic focal cortical dysplasias (FCDs) from structural MRI. FCDs are difficult to visualize on MRI but often amenable surgical resection. We aimed develop an open-source, interpretable, surface-based machine-learning automatically identify heterogeneous data epilepsy surgery centres worldwide. The Multi-centre Epilepsy...
Drug-resistant focal epilepsy is often caused by cortical dysplasias (FCDs). The distribution of these lesions across the cerebral cortex and impact lesion location on clinical presentation surgical outcome are largely unknown. We created a neuroimaging cohort patients with individually mapped FCDs to determine factors associated predictors postsurgical outcome.
Importance A leading cause of surgically remediable, drug-resistant focal epilepsy is cortical dysplasia (FCD). FCD challenging to visualize and often considered magnetic resonance imaging (MRI) negative. Existing automated methods for detection are limited by high numbers false-positive predictions, hampering their clinical utility. Objective To evaluate the efficacy interpretability graph neural networks in automatically detecting lesions on MRI scans. Design, Setting, Participants In this...
When planning for epilepsy surgery, multiple potential sites resection may be identified through anatomical imaging. Magnetoencephalography (MEG) using optically pumped sensors (OP-MEG) is a non-invasive functional neuroimaging technique which could used to help identify the epileptogenic zone from these candidate regions. Here we test utility of a-priori information imaging differentiating lesion with OP-MEG. We investigate number scenarios: whether use rigid or flexible sensor arrays,...
Abstract Background and purpose Magnetic resonance imaging (MRI) is essential in the diagnosis of pharmacoresistant epilepsy (PRE), because patients with lesions detected by MRI have a better prognosis after surgery. Focal cortical dysplasia (FCD) one most frequent etiologies PRE but can be difficult to identify MRI. Voxel‐based morphometric analysis programs, like Morphometric Analysis Program (MAP), been developed help improve detection. Our objective was evaluate clinical usefulness MAP...
Introduction: The overall combined prevalence of anxiety and depression in patients with epilepsy has been estimated at 20.2 22.9%, respectively, is considered more severe drug-refractory epilepsy. Patients admitted to monitoring units constitute a particular group. Also, psychogenic non-epileptic seizures can reach than 20% all admissions. This study aims characterize these symptoms large cohort for evaluation tertiary center. Materials Methods: was conducted among 493 consecutive (age:...
Coupled with stereo-electroencephalography (SEEG), radiofrequency thermocoagulation (RFTC) has emerged as a therapeutic alternative for patients refractory focal epilepsy, proven safe but highly variable results across studies. The authors aimed to describe the outcomes and safety of SEEG-RFTC, focusing on MRI-negative epilepsy.A retrospective observational study was conducted evaluated by SEEG in authors' center. Of 84 total cases, 55 underwent RFTC, 31 epilepsies that were ultimately...
Complex attention and non-verbal fluency tasks are used in neuropsychological assessments with the aim of exploring subdomains executive function. The purpose this study is to provide norms age-, education-, sex-adjusted data for Delis Kaplan-Design Fluency Test (DK-DFT), Color Trails (CTT), Dual Task (DT) as part NEURONORMA-Plus project.
El test Free and Cued Selective Reminding Test (FCSRT) es una prueba de uso extendido para evaluar la memoria episódica verbal, principalmente en el ámbito enfermedad Alzheimer. Existe versión española con datos normativos proveniente del proyecto NEURONORMA.ES. Disponer versiones alternativas equivalentes las pruebas resulta útil seguimiento los pacientes práctica clínica. objetivo presente estudio ofrecer alternativa a original, denominada «B», estudiar su equivalencia original (A) y...
Abstract The principles governing the formation of episodic memories from continuous stream sensory stimuli are not fully understood. Theoretical models hippocampus propose that representational format comprise oscillations in theta frequency band (2-8 Hz) set time boundaries which discrete events bound encoded gamma range (>30 Hz). We investigated this temporal segmentation and binding process by analyzing intracranial EEG (iEEG) surgically implanted epileptic patients performing a...
ResumenObjetivo: El presente estudio tiene como objetivo proporcionar normas y ajustes para edad, educación género el Wisconsin Card Sorting Test (WCST), la Figura Compleja Modificada de Taylor (FCMT) Ruff-Light Trail Learning (RULIT) parte del proyecto NEURONORMA-Plus.Método: La muestra consiste en 308 individuos cognitivamente sanos entre 18 92 años.Se proporcionan tablas convertir las puntuaciones brutas escalares ajustadas por edad tras aplicar modelos regresión independientes 2 grupos...
OBJECTIVE Stereo-electroencephalography (SEEG)–guided radiofrequency thermocoagulation (RFTC) is being used incrementally in the invasive diagnosis of epilepsy. There currently a lack information regarding potential cognitive consequences extended use this technique. This work describes, for first time, outcomes after RFTC patients with temporal lobe epilepsy (TLE), evaluated longitudinally and using control group. METHODS Forty-eight adult drug-resistant unilateral TLE (30 RFTC-treated 18...
Abstract Drug-resistant focal epilepsy is often caused by cortical dysplasias (FCDs). The distribution of these lesions across the cerebral cortex and impact lesion location on clinical presentation surgical outcome are largely unknown. We created a neuroimaging cohort patients with individually mapped FCDs to determine factors associated predictors postsurgical outcome. Multi-centre Epilepsy Lesion Detection (MELD) project collated retrospective 580 attributed FCD from 20 centres worldwide....
Abstract Introduction One outstanding challenge for machine learning in diagnostic biomedical imaging is algorithm interpretability. A key application the identification of subtle epileptogenic focal cortical dysplasias (FCDs) from structural MRI. FCDs are difficult to visualise on MRI but often amenable surgical resection. We aimed develop an open-source, interpretable, surface-based machine-learning automatically identify heterogeneous data epilepsy surgery centres worldwide. Methods The...
The present study aims to provide norms and age-, education-, sex-adjusted data for the Wisconsin Card Sorting Test (WCST), Modified Taylor Complex Figure (MTCF), Ruff-Light Trail Learning (RULIT) as part of NEURONORMA-Plus project.
Complex attention and non-verbal fluency tasks are used in neuropsychological assessments with the aim of exploring subdomains executive function. The purpose this study is to provide norms age-, education-, sex-adjusted data for Delis Kaplan-Design Fluency Test (DK-DFT), Color Trails (CTT), Dual Task (DT) as part NEURONORMA-Plus project.