W. Herbst

ORCID: 0000-0002-2238-8785
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About
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Research Areas
  • Animal Virus Infections Studies
  • Viral gastroenteritis research and epidemiology
  • Virus-based gene therapy research
  • Veterinary medicine and infectious diseases
  • Microbial infections and disease research
  • Animal Disease Management and Epidemiology
  • Herpesvirus Infections and Treatments
  • Virology and Viral Diseases
  • Respiratory viral infections research
  • Animal health and immunology
  • SARS-CoV-2 and COVID-19 Research
  • Turtle Biology and Conservation
  • Influenza Virus Research Studies
  • Viral Infections and Vectors
  • Concrete and Cement Materials Research
  • Viral Infections and Immunology Research
  • Vector-borne infectious diseases
  • Aquaculture disease management and microbiota
  • Congenital Anomalies and Fetal Surgery
  • Bird parasitology and diseases
  • Vector-Borne Animal Diseases
  • Poxvirus research and outbreaks
  • Insect and Pesticide Research
  • 3D Printing in Biomedical Research
  • Cancer Research and Treatments

Justus-Liebig-Universität Gießen
2011-2024

Institut für Hygiene und Umwelt
1987-2004

Institute of Medical Microbiology and Hygiene
2000

Psychiatric Association of Turkey
1987

University of Veterinary Medicine Hannover, Foundation
1983

The University of Texas Medical Branch at Galveston
1960-1962

Abstract The coronavirus strain HECV‐4408 was isolated from diarrhea fluid of a 6‐year‐old child with acute and propagated in human rectal tumor (HRT‐18) cells. Electron microscopy revealed particles the sample infected HRT‐18 cell cultures. This virus possessed hemagglutinating acetylesterase activities caused cytopathic effects cells but not MDBK, GBK FE One four S‐specific monoclonal antibodies reacted Western blots HECV‐4408, BCV‐L9 BCV‐LY138 HCV‐OC43, two HCV‐OC43. N‐specific all these...

10.1002/jmv.1890440207 article EN Journal of Medical Virology 1994-10-01

Faecal samples from suckling (n 205) and weaned piglets 82) with diarrhoea 24 farms in Southern Germany were examined for shedding of important metazoic parasitic, viral bacterial pathogens using culture, microscopic electronmicroscopic methods.Escherichia coli isolates tested further the enterotoxin genes est-Ia elt-I by colony blot hybridization.Isospora suis was diagnosed 26.9 % Cryptosporidium parvum 1.4 investigated.The proportion coronavirus-positive animals 13.4 4 positive...

10.1046/j.1439-0450.2001.00431.x article EN Journal of Veterinary Medicine Series B 2001-03-02

Brucella canis is one of many responsible pathogens discospondylitis in dogs and infections require specific management. Little known about the epidemiologic situation Europe. The purpose study was to get insights into occurrence brucellosis database a European veterinary laboratory screened for positive samples. Additionally, medical records hospital Germany were diagnosis brucellosis. received samples from 20 countries testing dogs: 3.7% submitted spp. PCR-positive (61/1,657), antibodies...

10.3389/fvets.2019.00151 article EN cc-by Frontiers in Veterinary Science 2019-05-31

Antimicrobial resistance (AMR) is considered one of the greatest threats to both human and animal health. Efforts address AMR include implementing antimicrobial stewardship programs introducing alternative treatment options. Nevertheless, effective infectious diseases caused by bacteria will still require identification development new agents. Eight different natural products were tested for activity against seven pathogenic bacterial species (Brachyspira sp., Chlamydia Clostridioides...

10.3390/antibiotics13020135 article EN cc-by Antibiotics 2024-01-30

ABSTRACT Jena virus (JV) is a bovine enteric calicivirus that causes diarrhea in calves. The approximately 30 nm diameter and has surface morphology similar to the human Norwalk virus. genome sequence of JV was recently described, been assigned genus Norovirus family Caliciviridae . In present study, capsid gene encoded by open reading frame 2 cloned into baculovirus transfer vector pFastBac 1, this used transform Escherichia coli generate recombinant bacmid. Transfection insect cells with...

10.1128/jcm.41.6.2300-2305.2003 article EN Journal of Clinical Microbiology 2003-06-01

The intestinal spirochete Brachyspira hyodysenteriae is an important pathogen in swine, causing mucohemorrhagic colitis a disease known as swine dysentery. Based on the detection of significant linkage disequilibrium multilocus sequence data, species considered to be clonal. An analysis genome Western Australian B. strain WA1 has been published, and current study 19 further strains from countries around world were sequenced with Illumina technology. genomes assembled aligned over 97.5%...

10.1371/journal.pone.0131050 article EN cc-by PLoS ONE 2015-06-22

Summary Four, 57 days old, African hunting dog puppies ( Lycaon pictus ) from one litter died within three weeks following vaccination with modified‐live canine distemper virus (CDV) and killed adenovirus type 1, parvovirus Leptospira icterohemorrhagiae canicola. 18 post vaccination, the animals developed neurologic disease characterized by episodes of grand mal seizures circling. Macroscopic, histological immunohistochemical studies revealed acute systemic CDV infection encephalopathy....

10.1111/j.1439-0450.1990.tb01048.x article DE Journal of Veterinary Medicine Series B 1990-01-12

Avian influenza viruses sporadically cross the species barrier to mammals, including humans, in which they may cause epidemic disease. Recently such an occurred due emergence of avian virus subtype H10N7 (Seal/H10N7) harbor seals (Phoca vitulina). This caused high mortality along north-west coast Europe and represented a potential risk for human health. To characterize spectrum lesions identify target cells viral distribution, findings 16 spontaneously infected with Seal/H10N7 are described....

10.1371/journal.pone.0159625 article EN cc-by PLoS ONE 2016-07-22

The mycoplasma strain ST 57T was isolated from the trachea of a clinically healthy, free-ranging white stork nestling in Nielitz, Mecklenburg-Western Pomerania, Germany. Strain grew fried-egg-shaped colonies on (SP4) agar plates and dependent sterol for growth. organism fermented glucose did not hydrolyse arginine or urea. optimal growth temperature 37 °C, with range 23 to 44 °C. 57Tcould be identified as representative any currently described species by alignment 16S rRNA gene sequence...

10.1099/ijsem.0.001220 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2016-06-06

Leech therapy is currently considered to be of high therapeutic value in medicine. However, feeding leeches with fresh animal blood during the maintenance and reproduction phase bears risk transmission zoonotic viruses patient. We hypothesize that this would abolished by subjecting quarantine measures prior use. The required duration depend on maximum survival time pathogens contaminated leeches. In order able estimate reliably, experiments were conducted enveloped non-enveloped mammalian...

10.1099/jmm.0.027250-0 article EN Journal of Medical Microbiology 2011-03-04

Summary Objective: A disease is described in juvenile tortoises (Testudo graeca and Geochelone elegans) consisting mainly of a soft carapace, plastron deformed skeleton. The aim this study was to determine histopathological lesions the biological properties isolated viruses. Materials methods: Clinical signs gross pathology were determined on diseased healthy appearing tortoises. Paraffin sections stained with HE, PAS Prussian Blue histologically examined. Terrapene heart (TH-1) cell...

10.1055/s-0038-1623777 article EN Tierärztliche Praxis Ausgabe K Kleintiere / Heimtiere 2014-01-01

Faecal samples from suckling ( n =205) and weaned piglets =82) with diarrhoea 24 farms in Southern Germany were examined for shedding of important metazoic parasitic, viral bacterial pathogens using culture, microscopic electronmicroscopic methods. Escherichia coli isolates tested further the enterotoxin genes est‐Ia elt‐I by colony blot hybridization. Isospora suis was diagnosed 26.9 % Cryptosporidium parvum 1.4 investigated. The proportion coronavirus‐positive animals 13.4 4 positive...

10.1111/j.1439-0450.2001.00431.x article EN Journal of Veterinary Medicine Series B 2001-03-02

Swine dysentery (SD) is an economically important diarrheal disease in pigs caused by different strongly hemolytic Brachyspira (B.) species, such as B. hyodysenteriae, suanatina and hampsonii. Possible associations of epidemiologic data, multilocus sequence types (STs) to virulence gene profiles antimicrobial susceptibility are rather scarce, particularly for hyodysenteriae isolates from Germany. In this study, (n = 116) isolated diarrheic between 1990 2016 Germany were investigated their...

10.1371/journal.pone.0190928 article EN cc-by PLoS ONE 2018-01-11
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